{"id":266113,"date":"2019-05-17T22:57:02","date_gmt":"2019-05-18T05:57:02","guid":{"rendered":"https:\/\/nai500.com\/?p=266113"},"modified":"2019-05-17T22:57:02","modified_gmt":"2019-05-18T05:57:02","slug":"%e7%9b%b8%e8%be%83%e8%af%ba%e5%8d%8e%e7%9a%84%e6%b3%b0%e7%ab%8b%e6%b2%99%ef%bc%8cpuma%e7%9a%84nerlynx%e5%9c%a8%e4%b9%b3%e8%85%ba%e7%99%8c%e8%af%95%e9%aa%8c%e4%b8%ad%e6%98%be%e7%a4%ba%e5%87%ba%e6%b2%bb","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2019\/05\/%e7%9b%b8%e8%be%83%e8%af%ba%e5%8d%8e%e7%9a%84%e6%b3%b0%e7%ab%8b%e6%b2%99%ef%bc%8cpuma%e7%9a%84nerlynx%e5%9c%a8%e4%b9%b3%e8%85%ba%e7%99%8c%e8%af%95%e9%aa%8c%e4%b8%ad%e6%98%be%e7%a4%ba%e5%87%ba%e6%b2%bb\/","title":{"rendered":"\u76f8\u8f83\u8bfa\u534e\u7684\u6cf0\u7acb\u6c99\uff0cPuma\u7684Nerlynx\u5728\u4e73\u817a\u764c\u8bd5\u9a8c\u4e2d\u663e\u793a\u51fa\u6cbb\u7597\u4f18\u52bf"},"content":{"rendered":"<p>\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u53ec\u5f00\u524d\uff0c\u751f\u7269\u79d1\u6280\u516c\u53f8Puma Biotechnology Inc\uff08NYSE: PBYI\uff09\u63d0\u4ea4\u4e86\u4e00\u4efd\u4f1a\u8bae\u6458\u8981\u3002\u6458\u8981\u663e\u793a\uff0c\u8be5\u516c\u53f8\u7684NALA\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c\u663e\u793a\uff0c\u76f8\u8f83\u8bfa\u534eNovartis\uff08NYSE: NVS\uff09\u7684\u6cf0\u7acb\u6c99\uff08\u62c9\u5e15\u66ff\u5c3c\uff09\u8054\u5408\u5e0c\u7f57\u8fbe\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u8be5\u516c\u53f8\u7684\u53e3\u670d\u6fc0\u9176\u6291\u5236\u5242Nerlynx\uff08\u6765\u90a3\u66ff\u5c3c\uff09\u548c\u7f57\u6c0f\u5316\u7597\u836f\u7269\u5e0c\u7f57\u8fbe\uff08\u5361\u57f9\u4ed6\u6ee8\uff09\u7684\u7ec4\u5408\u7597\u6cd5\u663e\u793a\u51fa\u6cbb\u7597\u4f18\u52bf\u3002<\/p>\n<p>NALA\u8bd5\u9a8c\u662f\u4e00\u9879\u591a\u56fd\u3001\u968f\u673a\u548c\u975e\u76f2\u7684\u4e09\u671f\u8bd5\u9a8c\uff0c\u53d7\u8bd5\u8005\u4e3a\u6b64\u524d\u63a5\u53d7\u4e24\u6b21\u6216\u4e24\u6b21\u4ee5\u4e0aHER2\u5b9a\u5411\u6cbb\u7597\u7684\u56db\u671fHER2\u9633\u6027\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u60a3\u8005\u3002\u8fd9\u4e9b\u60a3\u8005\u6309\u71671:1\u7684\u6bd4\u4f8b\u968f\u673a\u5206\u4e3a\u4e24\u7ec4\uff0c\u5206\u522b\u63a5\u53d7Nerlynx+\u5e0c\u7f57\u8fbe\u6216\u6cf0\u7acb\u6c99+\u5e0c\u7f57\u8fbe\u7ec4\u5408\u7597\u6cd5\u7684\u6cbb\u7597\u3002\u8be5\u8bd5\u9a8c\u7684\u8054\u5408\u4e3b\u8981\u7ec8\u70b9\u4e3a\u65e0\u8fdb\u5c55\u751f\u5b58\u7387\uff08PFS\uff09\u548c\u603b\u751f\u5b58\u7387\uff08OS\uff09\u3002\u6b21\u8981\u7ec8\u70b9\u4e3a\u7814\u7a76\u4eba\u5458\u8bc4\u4f30PFS\u3001\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u3001\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DoR\uff09\u3001\u4e34\u5e8a\u83b7\u76ca\u7387\uff08CBR\uff09\u3001\u75c7\u72b6\u6027\u8f6c\u79fb\u6027\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u5e72\u9884\u65f6\u95f4\u3001\u5b89\u5168\u6027\u4ee5\u53ca\u60a3\u8005\u62a5\u544a\u5065\u5eb7\u7ed3\u5c40\u3002<\/p>\n<p>\u8bd5\u9a8c\u8bc4\u4f30\u4e86621\u540d\u60a3\u8005\u3002Nerlynx-\u5e0c\u7f57\u8fbe\u6cbb\u7597\u7ec4\u57286\u81f312\u4e2a\u6708\u7684PFS\u5206\u522b\u4e3a47%\u548c38%\uff0c\u6cf0\u7acb\u6c99-\u5e0c\u7f57\u8fbe\u7ec4\u540c\u671f\u7684PFS\u5206\u522b\u4e3a29%\u548c15%\u3002\u6b64\u5916\uff0c\u540c\u4e00\u65f6\u95f4\u70b9Nerlynx-\u5e0c\u7f57\u8fbe\u7ec4\u7684OS\u4e3a33%\uff0c\u7a0d\u9ad8\u4e8e\u6cf0\u7acb\u6c99-\u5e0c\u7f57\u8fbe\u7ec4\u768427%\uff0c\u4f46\u5e76\u4e0d\u5177\u5907\u7edf\u8ba1\u4e0a\u7684\u663e\u8457\u6027\u3002\u4e24\u7ec4\u7684\u8010\u53d7\u6027\u7c7b\u4f3c\uff0c\u540c\u65f6\u5e76\u672a\u89c2\u6d4b\u5230\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u53f7\u3002<\/p>\n<p>Nerlynx\u662fPuma\u7684\u9996\u4e2a\u5546\u4e1a\u5316\u4ea7\u54c1\uff0c\u8be5\u53e3\u670d\u836f\u7269\u9488\u5bf9\u65e9\u671f\u4e73\u817a\u764c\u624b\u672f\u540e\u5b8c\u6210\u8d6b\u8d5b\u6c40\uff08\u66f2\u59a5\u73e0\u5355\u6297\uff09\u6cbb\u7597\u7684\u60a3\u8005\u3002\u57285\u67089\u65e5\u53d1\u5e03\u7684\u8d22\u62a5\u5f53\u4e2d\uff0c\u8be5\u516c\u53f8\u516c\u544a2019\u5e74\u4e00\u5b63\u5ea6\u7684\u9500\u552e\u989d\u6536\u5165\u5168\u90e8\u6765\u81ea\u4e8eNerlynx\uff08$4560\u4e07\uff09\uff0c\u4e0a\u4e00\u5e74\u540c\u671f\u4e3a$3600\u4e07\u3002\u8be5\u5b63\u51c0\u4e8f\u635f$1010\u4e07\uff0c\u5408\u6bcf\u80a1$0.26\u3002\u975eGAAP\u8c03\u6574\u540e\u51c0\u5229\u6da6\u4e3a$810\u4e07\uff0c\u5408\u57fa\u672c\u6bcf\u80a1\u6536\u76ca$0.21\uff0c\u5408\u7a00\u91ca\u540e\u6bcf\u80a1\u6536\u76ca$0.20\u3002Puma\u8463\u4e8b\u957f\u3001\u9996\u5e2d\u6267\u884c\u5b98\u517c\u603b\u88c1Alan H. 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