{"id":268621,"date":"2019-06-11T18:15:24","date_gmt":"2019-06-12T01:15:24","guid":{"rendered":"https:\/\/nai500.com\/?p=268621"},"modified":"2019-06-11T18:15:24","modified_gmt":"2019-06-12T01:15:24","slug":"deciphera%e5%85%ac%e5%8f%b8%e4%b8%8e%e5%86%8d%e9%bc%8e%e5%8c%bb%e8%8d%af%e8%be%be%e6%88%90ripretinib%e5%9c%a8%e5%a4%a7%e4%b8%ad%e5%8d%8e%e5%8c%ba%e7%9a%84%e7%8b%ac%e5%ae%b6%e6%8e%88%e6%9d%83%e5%90%88","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2019\/06\/deciphera%e5%85%ac%e5%8f%b8%e4%b8%8e%e5%86%8d%e9%bc%8e%e5%8c%bb%e8%8d%af%e8%be%be%e6%88%90ripretinib%e5%9c%a8%e5%a4%a7%e4%b8%ad%e5%8d%8e%e5%8c%ba%e7%9a%84%e7%8b%ac%e5%ae%b6%e6%8e%88%e6%9d%83%e5%90%88\/","title":{"rendered":"Deciphera\u516c\u53f8\u4e0e\u518d\u9f0e\u533b\u836f\u8fbe\u6210Ripretinib\u5728\u5927\u4e2d\u534e\u533a\u7684\u72ec\u5bb6\u6388\u6743\u5408\u4f5c"},"content":{"rendered":"
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Deciphera Pharmaceuticals, Inc.\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aDCPH\uff09\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u89e3\u51b3\u80bf\u7624\u8010\u836f\u6027\u5173\u952e\u673a\u5236\u7684\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u518d\u9f0e\u533b\u836f\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aZLAB\uff09\u662f\u4e00\u5bb6\u603b\u90e8\u4f4d\u4e8e\u4e2d\u56fd\u548c\u7f8e\u56fd\u7684\u521b\u65b0\u751f\u7269\u5236\u836f\u516c\u53f8\u3002\u53cc\u65b9\u5ba3\u5e03\u8fbe\u6210\u72ec\u5bb6\u6388\u6743\u534f\u8bae\uff0c\u4ee5\u63a8\u8fdbRipretinib\u5728\u5927\u4e2d\u534e\u533a\uff08\u4e2d\u56fd\u5927\u9646\u3001\u9999\u6e2f\u3001\u6fb3\u95e8\u548c\u53f0\u6e7e\uff09\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002Ripretinib\u662f\u7531Deciphera\u516c\u53f8\u7814\u53d1\u7684\u4e00\u79cd\u8bd5\u9a8c\u6027\u53e3\u670d\u6fc0\u9176\u5f00\u5173\u8c03\u63a7\u6291\u5236\u5242\uff0c\u7528\u4e8e\u6cbb\u7597\u7531KIT\u6216PDGFR\u03b1\u57fa\u56e0\u9a71\u52a8\u7684\u80c3\u80a0\u9053\u95f4\u8d28\u7624\uff08Gastrointestinal Stromal Tumors, GIST\uff09\u548c\u5176\u4ed6\u5b9e\u4f53\u80bf\u7624\u3002<\/p>\n

\u6839\u636e\u534f\u8bae\u6761\u6b3e\uff0cDeciphera\u516c\u53f8\u5c06\u83b7\u5f972000\u4e07\u7f8e\u5143\u7684\u73b0\u91d1\u9884\u4ed8\u6b3e\uff0c\u5e76\u6709\u8d44\u683c\u83b7\u5f97\u6700\u9ad8\u8fbe1.85\u4ebf\u7f8e\u5143\u7684\u6f5c\u5728\u5f00\u53d1\u548c\u5546\u4e1a\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002\u6b64\u5916\uff0c\u518d\u9f0e\u533b\u836f\u5c06\u6839\u636eRipretinib\u5728\u5927\u4e2d\u534e\u533a\u7684\u5e74\u5ea6\u51c0\u9500\u552e\u989d\u5411Deciphera\u652f\u4ed8\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u3002\u518d\u9f0e\u533b\u836f\u5c06\u83b7\u5f97Ripretinib\u5728\u5927\u4e2d\u534e\u533a\u7684\u72ec\u5bb6\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u6743\u5229\u3002\u518d\u9f0e\u533b\u836f\u5c06\u51ed\u501f\u5176\u5728\u6ce8\u518c\u548c\u4e34\u5e8a\u9886\u57df\u7684\u4e13\u4e1a\u80fd\u529b\u9886\u5bfcRipretinib\u5728\u8be5\u533a\u57df\u7684\u4e34\u5e8a\u5f00\u53d1\u3002Deciphera\u516c\u53f8\u8ba1\u5212\u5c06\u4e2d\u56fd\u4e34\u5e8a\u4e2d\u5fc3\u7eb3\u5165\u6b63\u5728\u8fdb\u884c\u7684\u5168\u7403\u2162\u671fINTRIGUE\u7814\u7a76\uff0c\u8be5\u7814\u7a76\u65e8\u5728\u5bf9\u6bd4Ripretinib\u4e0e\u8212\u5c3c\u66ff\u5c3c\u4f5c\u4e3a\u4e8c\u7ebf\u6cbb\u7597\u65b9\u6848\u5728\u80c3\u80a0\u9053\u95f4\u8d28\u7624\u60a3\u8005\u4e2d\u7684\u7597\u6548\u3002<\/p>\n

Deciphera\u516c\u53f8\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98Steve Hoerter\u8868\u793a\uff1a\u201c\u6211\u4eec\u76f8\u4fe1\u518d\u9f0e\u533b\u836f\u662fRipretinib\u672a\u6765\u5728\u5927\u4e2d\u534e\u533a\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u7684\u6700\u7406\u60f3\u7684\u5408\u4f5c\u4f19\u4f34\u3002\u518d\u9f0e\u533b\u836f\u5728\u5feb\u901f\u63a8\u8fdb\u521b\u65b0\u5019\u9009\u836f\u7269\u5f00\u53d1\u7684\u4f18\u79c0\u7ecf\u9a8c\u5c06\u6210\u4e3a\u52a0\u901fRipretinib\u5728\u5927\u4e2d\u534e\u5730\u533a\u5f00\u53d1\u7684\u91cd\u8981\u52a9\u529b\u3002\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e0e\u518d\u9f0e\u533b\u836f\u5408\u4f5c\uff0c\u4e3a\u5927\u4e2d\u534e\u533a\u80c3\u80a0\u9053\u95f4\u8d28\u7624\u60a3\u8005\u63d0\u4f9b\u6cbb\u7597\u9009\u62e9\u3002\u201d<\/p>\n

\u82f1\u6587\u6765\u6e90\uff1aBiospace<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Deciphera Pharmaceuticals, Inc.\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aDCPH\uff09\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u89e3\u51b3\u80bf […]<\/p>\n","protected":false},"author":9,"featured_media":268618,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[427],"tags":[820,513,455,747,925,459],"class_list":["post-268621","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hans","tag-820","tag-513","tag-455","tag-747","tag-925","tag-459","sectors-life-science-zh-hans","locations-china-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/268621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=268621"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/268621\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/268618"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=268621"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=268621"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=268621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}