{"id":284654,"date":"2019-08-17T00:00:00","date_gmt":"2019-08-17T07:00:00","guid":{"rendered":"http:\/\/62.151.178.150\/blog\/2019\/08\/fda%e6%89%b9%e5%87%86genentech%e7%9a%84rozlytrek%ef%bc%8c%e7%94%a8%e4%ba%8e%e6%b2%bb%e7%96%97%e4%b8%a4%e7%a7%8d%e7%bd%95%e8%a7%81%e7%9a%84%e7%99%8c%e7%97%87\/"},"modified":"2019-08-17T00:00:00","modified_gmt":"2019-08-17T07:00:00","slug":"fda%e6%89%b9%e5%87%86genentech%e7%9a%84rozlytrek%ef%bc%8c%e7%94%a8%e4%ba%8e%e6%b2%bb%e7%96%97%e4%b8%a4%e7%a7%8d%e7%bd%95%e8%a7%81%e7%9a%84%e7%99%8c%e7%97%87","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2019\/08\/fda%e6%89%b9%e5%87%86genentech%e7%9a%84rozlytrek%ef%bc%8c%e7%94%a8%e4%ba%8e%e6%b2%bb%e7%96%97%e4%b8%a4%e7%a7%8d%e7%bd%95%e8%a7%81%e7%9a%84%e7%99%8c%e7%97%87\/","title":{"rendered":"FDA\u6279\u51c6Genentech\u7684Rozlytrek\uff0c\u7528\u4e8e\u6cbb\u7597\u4e24\u79cd\u7f55\u89c1\u7684\u764c\u75c7"},"content":{"rendered":"<p>\u745e\u58eb\u5236\u836f\u5de8\u5934\u7f57\u6c0f\u63a7\u80a1Roche Holding\uff08NASDAQOTH: RHHBY\uff09\u7684\u5b50\u516c\u53f8Genentech\u5468\u56db\u665a\u95f4\u8868\u793a\uff0c\u516c\u53f8\u7684\u4e2a\u6027\u5316\u6297\u764c\u53e3\u670d\u836f\u7269Rozlytrek\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u7684\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597ROS1\u9633\u6027\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u7684\u6210\u4eba\u60a3\u8005\u3002\u6b64\u5916\uff0cRozlytrek\u8fd8\u83b7\u5f97\u4e86\u795e\u7ecf\u8425\u517b\u6027\u916a\u6c28\u9178\u53d7\u4f53\u6fc0\u9176\uff08NTRK\uff09\u57fa\u56e0\u878d\u5408\u5b9e\u4f53\u7624\u6cbb\u7597\u7684\u52a0\u901f\u5ba1\u6279\u8d44\u683c\u3002  Genentech\u8868\u793a\uff0c\u8fd9\u662f\u9996\u6b3e\u540c\u65f6\u4ee5ROS1\u548cNTRK\u4e3a\u9776\u70b9\u7684\u9776\u5411\u836f\u7269\uff0c\u5e76\u4e14\u5bf9\u4e8e\u5df2\u7ecf\u6269\u6563\u81f3\u8111\u90e8\u7684\u764c\u75c7\u4e5f\u6709\u7597\u6548\u3002Rozlytrek\u662f\u4e00\u79cd\u80bf\u7624\u4e0d\u786e\u5b9a\u7684\u764c\u75c7\u6cbb\u7597\u624b\u6bb5\uff0c\u5373\u4ee5\u4e00\u4e2a\u5177\u4f53\u7684\u81f4\u764c\u57fa\u56e0\u91cd\u6392\uff08\u8bf8\u5982NTRK\uff09\u4e3a\u9776\u70b9\uff0c\u800c\u65e0\u9700\u8003\u8651\u80bf\u7624\u7684\u539f\u53d1\u4f4d\u7f6e\u3002  \u7f57\u6c0f\u8868\u793a\uff0cNTRK\u57fa\u56e0\u878d\u5408\u5728\u5f88\u591a\u96be\u6cbb\u6027\u5b9e\u4f53\u7624\u5f53\u4e2d\u90fd\u6709\u53d1\u73b0\uff0c\u5176\u4e2d\u5305\u62ec\u80f0\u817a\u3001\u7532\u72b6\u817a\u3001\u553e\u817a\u3001\u4e73\u817a\u3001\u7ed3\u80a0\u76f4\u80a0\u4ee5\u53ca\u80ba\u3002\u4e0d\u8fc7\uff0c\u8fd9\u4e9b\u80bf\u7624\u7684\u8bca\u65ad\u975e\u5e38\u56f0\u96be\u3002\u7f57\u6c0f\u8868\u793a\uff0cNTRK\u57fa\u56e0\u878d\u5408\u7684\u751f\u7269\u6807\u5fd7\u7269\u68c0\u6d4b\u662f\u76ee\u524d\u786e\u5b9a\u60a3\u8005\u662f\u5426\u9002\u7528\u4e8eRozlytrek\u6cbb\u7597\u7684\u552f\u4e00\u624b\u6bb5\u3002  \u4eca\u5e746\u6708\uff0cRozlytrek\u9996\u6b21\u5728\u65e5\u672c\u83b7\u6279\u3002  FDA\u7684\u6279\u6587\u57fa\u4e8e\u5173\u952e\u7684\u4e8c\u671fSTARTRK-2\uff0c\u4e00\u671fSTARTRK-1\u4ee5\u53ca\u4e00\u671fALKA-372-001\u8bd5\u9a8c\u7684\u7efc\u5408\u5206\u6790\uff0c\u4ee5\u53ca\u4e00\/\u4e8c\u671fSTARTRK-NG\u7814\u7a76\u7684\u6570\u636e\u3002  Genentech\u8868\u793a\uff0c78%\u7684ROS1\u9633\u6027\uff0c\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u7684\u80bf\u7624\u840e\u7f29\u3002\u6b64\u5916\uff0c\u8d85\u8fc7\u4e00\u534a\u7684NTRK\u57fa\u56e0\u878d\u5408\u9633\u6027\uff0c\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\u60a3\u8005\u7684\u80bf\u7624\u840e\u7f29\u300210\u79cd\u80bf\u7624\u7c7b\u578b\u89c2\u5bdf\u5230\u5ba2\u89c2\u7f13\u89e3\u7387\u3002STARTRK-NG\u7814\u7a76\u4e2d\uff0cNTRK\u878d\u5408\u9633\u6027\u5b9e\u4f53\u7624\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u60a3\u8005\uff08\u5305\u62ec\u539f\u53d1\u6027\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u80bf\u7624\u60a3\u8005\uff09\u7684\u80bf\u7624\u4e5f\u840e\u7f29\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u745e\u58eb\u5236\u836f\u5de8\u5934\u7f57\u6c0f\u63a7\u80a1Roche Holding\uff08NASDAQOTH: RHHBY\uff09\u7684\u5b50\u516c\u53f8Genentech\u5468 [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":284655,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[193,430],"tags":[820,455,747,925,459],"class_list":["post-284654","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized_zh-hans","category-trends-strategies-zh-hans","tag-820","tag-455","tag-747","tag-925","tag-459","sectors-life-science-zh-hans","locations-us-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/284654","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=284654"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/284654\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/284655"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=284654"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=284654"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=284654"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}