{"id":297247,"date":"2019-10-09T20:00:28","date_gmt":"2019-10-10T03:00:28","guid":{"rendered":"https:\/\/nai500.com\/blog\/2019\/10\/chi-med-starts-syk-inhibitor\/"},"modified":"2019-10-09T20:02:02","modified_gmt":"2019-10-10T03:02:02","slug":"%e5%92%8c%e8%ae%b0%e4%b8%ad%e5%9b%bd%e5%8c%bb%e7%96%97%e7%a7%91%e6%8a%80-syk%e6%8a%91%e5%88%b6%e5%89%82","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2019\/10\/%e5%92%8c%e8%ae%b0%e4%b8%ad%e5%9b%bd%e5%8c%bb%e7%96%97%e7%a7%91%e6%8a%80-syk%e6%8a%91%e5%88%b6%e5%89%82\/","title":{"rendered":"\u548c\u8bb0\u4e2d\u56fd\u533b\u7597\u79d1\u6280\u8fdb\u884cSyk\u6291\u5236\u5242\u7684\u5168\u7403\u8bd5\u9a8c"},"content":{"rendered":"<p>\u548c\u8bb0\u4e2d\u56fd\u533b\u7597\u79d1\u6280\u5df2\u5f00\u59cb\u5bf9\u5176\u65b0\u578b\u5c0f\u5206\u5b50Syk\u6291\u5236\u5242\u5728\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6dcb\u5df4\u7624\u60a3\u8005\u4e2d\u8fdb\u884c\u5168\u7403I \/ Ib\u671f\u7814\u7a76\u3002\u8be5\u8bd5\u9a8c\u7684\u4e3b\u8981\u7ec8\u70b9\u662f\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\uff0c\u5c3d\u7ba1\u8fd8\u5c06\u76d1\u6d4bPK\u548c\u5ba2\u89c2\u7f13\u89e3\u7387\u3002 \u548c\u8bb0\u4e2d\u56fd\u533b\u7597\u79d1\u6280\u671f\u671b\uff0c\u7b2c\u4e8c\u4ee3Syk\u6291\u5236\u5242HMPL-523\u4e0e\u7b2c\u4e00\u4ee3\u5019\u9009\u836f\u7269\u76f8\u6bd4\uff0c\u5f15\u8d77\u7684\u5b89\u5168\u6027\u95ee\u9898\u66f4\u5c11\u3002\u5728\u8f83\u65e9\u7684\u6fb3\u5927\u5229\u4e9a\u8bd5\u9a8c\u4e2d\uff0cHMPL-523\u663e\u793a\u4e86\u53ef\u63a5\u53d7\u7684\u5b89\u5168\u6027\u3002\u8be5\u5019\u9009\u836f\u7269\u8fd8\u5728\u4e00\u9879\u4e2d\u56fd\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u60a3\u8005\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u63a5\u53d7\u6d4b\u8bd5\u3002<\/p>\n<p>\u82f1\u6587\u6765\u6e90\uff1aChina Biotoday<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hutchison China MediTech (Chi-Med) has started a global Phase I\/Ib study of its novel small molecule Syk inhibitor in patients with relapsed or refractory lymphoma. The primary endpoints of the trial are safety and tolerability, though PK and objective response rates will also be monitored. <\/p>\n","protected":false},"author":9,"featured_media":270775,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[427],"tags":[820,455,459],"class_list":["post-297247","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hans","tag-820","tag-455","tag-459","sectors-life-science-zh-hans","locations-china-zh-hans","exchange--zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/297247","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=297247"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/297247\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/270775"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=297247"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=297247"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=297247"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}