{"id":297928,"date":"2019-10-11T22:30:08","date_gmt":"2019-10-12T05:30:08","guid":{"rendered":"https:\/\/nai500.com\/?p=297928"},"modified":"2019-10-11T22:30:38","modified_gmt":"2019-10-12T05:30:38","slug":"%e5%ba%b7%e6%9c%b4%e7%94%9f%e7%89%a9%e5%ae%8c%e6%88%90%e7%99%8c%e7%97%87%e5%85%8d%e7%96%ab%e8%b0%83%e8%8a%82%e5%89%82%e4%b8%80%e6%9c%9f%e8%af%95%e9%aa%8c","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2019\/10\/%e5%ba%b7%e6%9c%b4%e7%94%9f%e7%89%a9%e5%ae%8c%e6%88%90%e7%99%8c%e7%97%87%e5%85%8d%e7%96%ab%e8%b0%83%e8%8a%82%e5%89%82%e4%b8%80%e6%9c%9f%e8%af%95%e9%aa%8c\/","title":{"rendered":"\u5eb7\u6734\u751f\u7269\u5b8c\u6210\u764c\u75c7\u514d\u75ab\u8c03\u8282\u5242\u4e00\u671f\u8bd5\u9a8c"},"content":{"rendered":"<p>\u4e0a\u6d77\u5eb7\u6734\u751f\u7269\u5b8c\u6210\u4e86KPG-818\u7684\u4e00\u671f\u4eba\u4f53\u8bd5\u9a8c\u3002KPG-818\u662f\u4e00\u79cd\u57fa\u4e8eCRBN E3\u6cdb\u7d20\u8fde\u63a5\u9176\u590d\u5408\u7269\u7684\u5c0f\u5206\u5b50\u514d\u75ab\u8c03\u8282\u5242\u3002\u5eb7\u6734\u516c\u53f8\u5e0c\u671bKPG-818\u80fd\u591f\u6709\u6548\u6cbb\u7597\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08SLE\uff09\u548c\u8840\u6db2\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u3002\u5728\u5065\u5eb7\u53d7\u8bd5\u8005\u4e2d\u8fdb\u884c\u7684\u4e00\u671f\u8bd5\u9a8c\u4e2d\uff0c\u5eb7\u6734\u516c\u53f8\u7684KPG-818\u6ca1\u6709\u663e\u793a\u4efb\u4f55\u5b89\u5168\u6027\u6216\u8010\u53d7\u6027\u95ee\u9898\u3002\u5eb7\u6734\u751f\u7269\u6b63\u5728\u5f00\u53d1\u7528\u4e8e\u764c\u75c7\u3001\u81ea\u8eab\u514d\u75ab\u548c\u708e\u6027\u75be\u75c5\u7684\u65b0\u578b\u5c0f\u5206\u5b50\u836f\u7269\u3002<\/p>\n<p>\u82f1\u6587\u6765\u6e90\uff1aChina Biotoday<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Kangpu Biopharma of Shanghai completed a first-in-human US Phase I trial of KPG-818, a small molecule immunomodulator based on the CRBN E3 ubiquitin ligase complex. Kangpu expects KPG-818 will be an effective treatment for systemic lupus erythematosus (SLE) and hematological malignancies. <\/p>\n","protected":false},"author":9,"featured_media":297925,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[427],"tags":[820,455,459],"class_list":["post-297928","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hans","tag-820","tag-455","tag-459","sectors-life-science-zh-hans","locations-china-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/297928","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=297928"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/297928\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/297925"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=297928"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=297928"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=297928"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}