{"id":308419,"date":"2019-12-04T22:00:50","date_gmt":"2019-12-05T06:00:50","guid":{"rendered":"https:\/\/nai500.com\/?p=308419"},"modified":"2019-12-04T22:01:19","modified_gmt":"2019-12-05T06:01:19","slug":"%e9%98%bb%e6%96%ad%e7%99%8c%e7%bb%86%e8%83%9e%e7%9a%84%e5%85%8d%e7%96%ab%e6%8a%91%e5%88%b6-ictcar014-%e8%8e%b7%e5%be%97%e6%96%b0%e8%8d%af%e4%b8%b4%e5%ba%8a%e8%af%95%e9%aa%8c%e6%89%b9%e5%87%86","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2019\/12\/%e9%98%bb%e6%96%ad%e7%99%8c%e7%bb%86%e8%83%9e%e7%9a%84%e5%85%8d%e7%96%ab%e6%8a%91%e5%88%b6-ictcar014-%e8%8e%b7%e5%be%97%e6%96%b0%e8%8d%af%e4%b8%b4%e5%ba%8a%e8%af%95%e9%aa%8c%e6%89%b9%e5%87%86\/","title":{"rendered":"\u963b\u65ad\u764c\u7ec6\u80de\u7684\u514d\u75ab\u6291\u5236ICTCAR014\u83b7\u5f97\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u6279\u51c6"},"content":{"rendered":"<p>\u751f\u7269\u6280\u672f\u516c\u53f8Innovative Cell Therapeutics\uff08ICT\uff09\u662f\u4e00\u5bb6\u5f00\u53d1\u7528\u4e8e\u8840\u764c\u548c\u5b9e\u4f53\u7624\u7684\u5d4c\u5408\u6297\u539f\u53d7\u4f53\uff08CAR\uff09T\u7ec6\u80de\u7597\u6cd5\u7684\u7efc\u5408\u5e73\u53f0\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u5ba3\u5e03\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u6279\u51c6\u8be5\u516c\u53f8\u7684ICTCAR014\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u8fd9\u662f\u4e00\u79cd\u9776\u5411CD19\u7684\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u7597\u6cd5\uff0c\u5176\u8868\u8fbe\u663e\u6027\u8d1f\u6027PD-1\u86cb\u767d\u6765\u963b\u65ad\u764c\u7ec6\u80de\u7684\u514d\u75ab\u6291\u5236\u3002ICT\u6709\u671b\u57282020\u5e74\u4e0a\u534a\u5e74\u5728\u4e00\u9879\u9488\u5bf9\u590d\u53d1\u6027\u6216\u96be\u6cbb\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08NHL\uff09\u7684\u60a3\u8005\uff08\u5305\u62ec\u80bf\u7624\u4e3aPD-L1\u9633\u6027\u60a3\u8005\uff09\u4e2d\u8fdb\u884c\u7f8e\u56fd\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p>ICT\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98Larry\uff08Lei\uff09Xiao\u535a\u58eb\u8bf4\uff1a\u201c\u6211\u4eec\u7684\u9996\u4e2a\u7f8e\u56fdIND\u5ba1\u6279\u662f\u6211\u4eec\u6269\u5927\u7f8e\u56fd\u6d3b\u52a8\u7684\u91cd\u8981\u4e00\u6b65\u3002\u57fa\u4e8e11\u6708\u4efd\u5728\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u534f\u4f1a\uff08SITC\uff09\u4e0a\u63d0\u4f9b\u7684\u4ee4\u4eba\u9f13\u821e\u7684\u6570\u636e\uff0c\u8be5\u6570\u636e\u663e\u793a\u5ba2\u89c2\u5e94\u7b54\u7387\u8d85\u8fc792%\uff0cICTCAR014\u8ba1\u5212\u7a81\u51fa\u4e86\u6211\u4eec\u5f00\u53d1\u65b0\u578b\u514d\u75ab\u7597\u6cd5\u7684\u52a0\u901f\u548c\u4f4e\u98ce\u9669\u65b9\u6cd5\u3002\u6211\u4eec\u7684\u53d1\u5c55\u7b56\u7565\u5c06\u4e2d\u56fd\u7684\u5feb\u901f\u6982\u5ff5\u9a8c\u8bc1\u4e34\u5e8a\u8bd5\u9a8c\u8f6c\u5316\u4e3a\u7f8e\u56fd\u548c\u5168\u7403\u53d1\u5c55\u8ba1\u5212\uff0c\u65e8\u5728\u901a\u8fc7\u5feb\u901f\u5ba1\u67e5\u9014\u5f84\u83b7\u5f97\u76d1\u7ba1\u90e8\u95e8\u7684\u6279\u51c6\u3002\u6211\u4eec\u671f\u5f85\u5c06ICTCAR014\u7eb3\u5165\u6211\u4eec\u7684\u9996\u4e2a\u7f8e\u56fd\u4e34\u5e8a\u8bd5\u9a8c\u3002\u201d<\/p>\n<p>ICTCAR014\u662f\u9776\u5411CD19\u7684\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u7597\u6cd5\uff0c\u5176\u8868\u8fbe\u663e\u6027\u8d1f\u6027PD-1\u86cb\u767d\u6765\u963b\u65ad\u764c\u7ec6\u80de\u7684\u514d\u75ab\u6291\u5236\u4f5c\u7528\u3002ICTCAR014\u88ab\u79f0\u4e3a\u201c\u94e0\u88c5\u201d CAR-T\u7ec6\u80de\u7597\u6cd5\uff0c\u5df2\u7ecf\u5728\u4e2d\u56fd\u7684\u6982\u5ff5\u9a8c\u8bc1\u4eba\u4f53\u8bd5\u9a8c\u4e2d\u663e\u793a\u51fa\u4ee4\u4eba\u9f13\u821e\u7684\u7ed3\u679c\u3002\u6b63\u5982ICT\u57282019\u5e7411\u6708\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u5b66\u4f1a\uff08SITC\uff09\u4f1a\u8bae\u4e0a\u7684\u6f14\u8bb2\u4e2d\u6240\u5f3a\u8c03\u7684\u90a3\u6837\uff0cICTCAR014\u572813\u4f8b\u590d\u53d1\u6027\u6216\u96be\u6cbb\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u60a3\u8005\u4e2d\u663e\u793a\u51fa92.3%\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff0853.8%\u7684\u5b8c\u5168\u7f13\u89e3; 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