{"id":312893,"date":"2020-01-14T19:41:44","date_gmt":"2020-01-15T03:41:44","guid":{"rendered":"https:\/\/nai500.com\/blog\/2020\/01\/hitgen-enters-into-dna-encoded-library-based-drug-discovery-research-collaboration-with-kymera\/"},"modified":"2020-01-14T19:41:59","modified_gmt":"2020-01-15T03:41:59","slug":"%e4%b8%ad%e5%9b%bd%e6%88%90%e9%83%bd%e5%85%88%e5%af%bc%e8%be%be%e6%88%90%e6%96%b0%e8%8d%af%e7%a0%94%e5%8f%91%e5%90%88%e4%bd%9c","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2020\/01\/%e4%b8%ad%e5%9b%bd%e6%88%90%e9%83%bd%e5%85%88%e5%af%bc%e8%be%be%e6%88%90%e6%96%b0%e8%8d%af%e7%a0%94%e5%8f%91%e5%90%88%e4%bd%9c\/","title":{"rendered":"\u4e2d\u56fd\u6210\u90fd\u5148\u5bfc\u8fbe\u6210\u65b0\u836f\u7814\u53d1\u5408\u4f5c"},"content":{"rendered":"<p>\u6210\u90fd\u5148\u5bfc\u5ba3\u5e03\uff0c\u5df2\u4e0eKymera Therapeutics\uff0cInc.\u8fdb\u884c\u4e86\u836f\u7269\u53d1\u73b0\u7814\u7a76\u5408\u4f5c\uff0c\u4ee5\u8bc6\u522bKymera\u611f\u5174\u8da3\u7684\u5c0f\u5206\u5b50\u7ebf\u7d22\u3002 \u6210\u90fd\u5148\u5bfc\u5c06\u57fa\u4e8eDNA\u7f16\u7801\u5316\u5408\u7269\u5e93\uff08DEL\uff09\u7684\u8bbe\u8ba1\uff0c\u5e94\u7528\u5176\u5e73\u53f0\u6280\u672f\u6765\u5408\u6210\u548c\u7b5b\u9009\u3001\u53d1\u73b0\u4e0e\u67d0\u4e9b\u9776\u6807\u7ed3\u5408\u7684\u5316\u5408\u7269\u3002\u9274\u5b9a\u51fa\u7684\u5316\u5408\u7269\u5c06\u72ec\u5bb6\u6388\u6743\u7ed9Kymera\u3002\u6839\u636e\u8be5\u534f\u8bae\u7684\u6761\u6b3e\uff0c\u6210\u90fd\u5148\u5bfc\u5c06\u6536\u5230\u672a\u62ab\u9732\u7684\u9884\u4ed8\u6b3e\uff0c\u5e76\u5c06\u6709\u8d44\u683c\u83b7\u5f97Kymera\u7684\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002<\/p>\n<p>\u6210\u90fd\u5148\u5bfc\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u517c\u9996\u5e2d\u6267\u884c\u5b98Jin Li\u535a\u58eb\u8bf4\uff1a\u201c\u6211\u4eec\u671f\u5f85\u4e0eKymera\u5408\u4f5c\uff0c\u4e3a\u4ed6\u4eec\u7684\u7814\u7a76\u751f\u6210\u5148\u5bfc\u5316\u5408\u7269\uff0c\u5c06\u8f6c\u5316\u836f\u7269\u5e26\u7ed9\u60a3\u8005\u3002\u5bf9\u4e8e\u6211\u4eec\u6765\u8bf4\uff0c\u8fd9\u662f\u4e0e\u65b0\u5174\u7684\u86cb\u767d\u8d28\u964d\u89e3\u9886\u57df\u7684\u9886\u5148\u516c\u53f8\u5408\u4f5c\u5f00\u53d1\u672a\u6765\u521b\u65b0\u7597\u6cd5\u7684\u7edd\u4f73\u673a\u4f1a\u3002 \u6210\u90fd\u5148\u5bfc\u7684\u6280\u672f\u7ed3\u5408\u4e86\u5206\u5b50\u751f\u7269\u5b66\u3001\u7ec4\u5408\u5316\u5b66\u3001\u9ad8\u901a\u91cf\u6d4b\u5e8f\u548c\u5148\u8fdb\u7684\u4fe1\u606f\u5b66\u7684\u5f3a\u5927\u529f\u80fd\u3002\u6211\u4eec\u76f8\u4fe1\uff0c\u6b64\u6b21\u5408\u4f5c\u5c06\u5de9\u56fa\u6210\u90fd\u5148\u5bfc\u5e73\u53f0\u5728\u8fc5\u901f\u53d1\u5c55\u7684DNA\u7f16\u7801\u5316\u5b66\u9886\u57df\u4e2d\u7684\u9886\u5bfc\u8005\u4f5c\u7528\u201d\u3002<\/p>\n<p>Kymera Therapeutics\u662f\u4e00\u5bb6\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u5f00\u521b\u4e86\u4e00\u79cd\u53d8\u9769\u6027\u7684\u65b0\u65b9\u6cd5\u6765\u6cbb\u7597\u4ee5\u524d\u65e0\u6cd5\u6cbb\u6108\u7684\u75be\u75c5\u3002\u8be5\u516c\u53f8\u6b63\u5728\u63a8\u8fdb\u6709\u9488\u5bf9\u6027\u7684\u86cb\u767d\u8d28\u964d\u89e3\u9886\u57df\uff0c\u5229\u7528\u4eba\u4f53\u56fa\u6709\u7684\u86cb\u767d\u8d28\u56de\u6536\u673a\u5236\u6765\u964d\u89e3\u5931\u8c03\u7684\u81f4\u75c5\u86cb\u767d\u8d28\u3002<\/p>\n<p>\u6210\u90fd\u5148\u5bfc\u662f\u4e00\u5bb6\u5feb\u901f\u53d1\u5c55\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u603b\u90e8\u4f4d\u4e8e\u4e2d\u56fd\u6210\u90fd\uff0c\u5728\u7f8e\u56fd\u8bbe\u6709\u5b50\u516c\u53f8\u3002 \u6210\u90fd\u5148\u5bfc\u5efa\u7acb\u4e86\u4e00\u4e2a\u884c\u4e1a\u9886\u5148\u7684\u5e73\u53f0\uff0c\u4ee5DNA\u7f16\u7801\u5316\u5408\u7269\u5e93\uff08DEL\uff09\u4e3a\u4e2d\u5fc3\u8fdb\u884c\u65e9\u671f\u836f\u7269\u53d1\u73b0\u7814\u7a76\u3002\u6210\u90fd\u5148\u5bfc\u7684DNA\u7f16\u7801\u5316\u5408\u7269\u5e93\u5305\u62ec\u6570\u4ebf\u65b0\u9896\u3001\u591a\u6837\u3001\u5c0f\u5206\u5b50\u548c\u5927\u73af\u5316\u5408\u7269\u7684\u7f16\u7801\u5316\u5408\u7269\u3002<\/p>\n<p>\u82f1\u6587\u6765\u6e90\uff1aBiospace<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hitgen Ltd today announced that it has entered into a drug discovery research collaboration with Kymera Therapeutics, Inc., to identify small molecule leads against targets of interest to Kymera. HitGen will apply its platform technology, based on the design, synthesis and screening of DNA-encoded libraries (DEL) to discover compounds that bind to certain targets. The identified compounds will be exclusively licensed to Kymera. Under the terms of the agreement, HitGen will receive an undisclosed upfront payment and will be eligible for milestone payments from Kymera.<\/p>\n","protected":false},"author":9,"featured_media":312883,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[427],"tags":[820,455,459],"class_list":["post-312893","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hans","tag-820","tag-455","tag-459","sectors-life-science-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/312893","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=312893"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/312893\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/312883"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=312893"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=312893"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=312893"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}