{"id":340914,"date":"2020-07-08T23:14:19","date_gmt":"2020-07-09T06:14:19","guid":{"rendered":"https:\/\/nai500.com\/?p=340914"},"modified":"2020-07-08T23:14:19","modified_gmt":"2020-07-09T06:14:19","slug":"%e5%86%8d%e9%bc%8e%e5%8c%bb%e8%8d%af%e5%92%8c-turning-point-%e8%be%be%e6%88%90%e5%a4%a7%e4%b8%ad%e5%8d%8e%e5%8c%ba%e7%8b%ac%e5%ae%b6%e6%8e%88%e6%9d%83%e5%90%88%e4%bd%9c","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2020\/07\/%e5%86%8d%e9%bc%8e%e5%8c%bb%e8%8d%af%e5%92%8c-turning-point-%e8%be%be%e6%88%90%e5%a4%a7%e4%b8%ad%e5%8d%8e%e5%8c%ba%e7%8b%ac%e5%ae%b6%e6%8e%88%e6%9d%83%e5%90%88%e4%bd%9c\/","title":{"rendered":"\u518d\u9f0e\u533b\u836f\u548cTurning Point\u8fbe\u6210\u5927\u4e2d\u534e\u533a\u72ec\u5bb6\u6388\u6743\u5408\u4f5c"},"content":{"rendered":"

Turning Point\u5c06\u83b7\u5f972500\u4e07\u7f8e\u5143\u7684\u524d\u671f\u9884\u4ed8\u6b3e\uff0c\u9ad8\u8fbe1.51\u4ebf\u7f8e\u5143\u7684\u6f5c\u5728\u91cc\u7a0b\u7891\u4ed8\u6b3e\u548c\u7279\u8bb8\u6743\u4f7f\u7528\u8d39<\/p>\n

\u7cbe\u786e\u80bf\u7624\u5b66\u516c\u53f8Turning Point Therapeutics, Inc.\uff08TPTX\uff09\u662f\u4e00\u5bb6\u81f4\u529b\u4e8e\u9488\u5bf9\u764c\u75c7\u9a71\u52a8\u57fa\u56e0\u6765\u5f00\u53d1\u65b0\u4e00\u4ee3\u80bf\u7624\u7cbe\u51c6\u7597\u6cd5\u7684\u516c\u53f8\u3002\u8be5\u516c\u53f8\u548c\u518d\u9f0e\u533b\u836f\uff08ZLAB\uff09\u8fbe\u6210\u72ec\u5bb6\u6388\u6743\u534f\u8bae\uff0c\u63a8\u8fdbTurning Point\u7684\u4e3b\u8981\u5019\u9009\u836f\u7269Repotrectinib\u5728\u5927\u4e2d\u534e\u533a\uff08\u4e2d\u56fd\u5185\u5730\u3001\u9999\u6e2f\u3001\u6fb3\u95e8\u548c\u53f0\u6e7e\uff09\u7684\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u3002<\/p>\n

\u6839\u636e\u8be5\u534f\u8bae\u7684\u6761\u6b3e\uff0c\u518d\u9f0e\u533b\u836f\u5c06\u83b7\u5f97\u5728\u5927\u4e2d\u534e\u533a\u5f00\u53d1\u548c\u5546\u4e1a\u5316repotrectinib\u7684\u4e13\u6709\u6743\u5229\uff0cTurning Point Therapeutics\u5c06\u83b7\u5f972500\u4e07\u7f8e\u5143\u7684\u9884\u4ed8\u6b3e\uff0c\u5e76\u6709\u53ef\u80fd\u83b7\u5f97\u9ad8\u8fbe1.51\u4ebf\u7f8e\u5143\u7684\u5f00\u53d1\u3001\u76d1\u7ba1\u548c\u9500\u552e\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002\u6839\u636erepotrectinib\u5728\u5927\u4e2d\u534e\u533a\u7684\u5e74\u5ea6\u51c0\u9500\u552e\u989d\uff0cTurn Point\u4e5f\u5c06\u6709\u8d44\u683c\u83b7\u5f97\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u3002<\/p>\n

Turning Point\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98Athena Countouriotis\u535a\u58eb\u8868\u793a\uff1a\u201c\u5927\u4e2d\u534e\u533a\u6bcf\u5e74\u6709\u8d85\u8fc770\u4e07\u540d\u65b0\u8bca\u65ad\u80ba\u764c\u60a3\u8005\uff0c\u800c\u518d\u9f0e\u533b\u836f\u5df2\u4e0d\u65ad\u8bc1\u660e\u5353\u8d8a\u7684\u4e34\u5e8a\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u80fd\u529b\u3002\u56e0\u6b64\uff0c\u518d\u9f0e\u533b\u836f\u662f\u5e2e\u52a9Repotrectinib\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u7684\u6700\u7406\u60f3\u5408\u4f5c\u4f19\u4f34\u3002\u540c\u65f6\u6211\u76f8\u4fe1\uff0c\u4e0e\u518d\u9f0e\u533b\u836f\u7684\u6218\u7565\u6027\u5408\u4f5c\u8fd8\u5c06\u52a0\u5febRepotrectinib\u5728\u5927\u4e2d\u534e\u533a\u7684\u5f00\u53d1\u3002\u201d<\/p>\n

repotrectinib\u7684TRIDENT-1 \u4e34\u5e8a2\u671f\u6ce8\u518c\u7814\u7a76\u76ee\u524d\u5728\u5168\u740311\u4e2a\u56fd\u5bb6\/\u5730\u533a\u8fdb\u884c\uff0c\u5e76\u62db\u52dfROS1\u9633\u6027\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u548cNTRK\u9633\u6027\u5b9e\u4f53\u7624\u60a3\u8005\u3002<\/p>\n

\u518d\u9f0e\u533b\u836f\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u675c\u83b9\u535a\u58eb\u8868\u793a\uff1a\u201c\u6211\u4eec\u5f88\u9ad8\u5174\u4e0eTurning Point\u8fbe\u6210\u8fd9\u9879\u534f\u8bae\u3002Repotrectinb\u4e0e\u518d\u9f0e\u533b\u836f\u73b0\u6709\u7684\u4ea7\u54c1\u7ba1\u7ebf\u9ad8\u5ea6\u534f\u540c\uff0c\u5e76\u5c06\u8fdb\u4e00\u6b65\u52a0\u5f3a\u6211\u4eec\u5728\u4e2d\u56fd\u7684\u9ad8\u53d1\u764c\u79cd\u5c24\u5176\u662f\u80ba\u764c\u9886\u57df\u7684\u5e03\u5c40\u3002\u6211\u4eec\u671f\u5f85\u5c06\u8fd9\u4e2a\u6f5c\u5728\u7684\u540c\u7c7b\u6700\u4f73\u836f\u7269\u5e26\u7ed9\u4e00\u7ebf\u4ee5\u53ca\u65e2\u5f80\u63a5\u53d7\u8fc7\u73b0\u6709\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\u6cbb\u7597\u5e76\u8010\u836f\u7684ROS1\u9633\u6027\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u548cNTRK\u9633\u6027\u7684\u5b9e\u4f53\u7624\u60a3\u8005\u3002\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

Turning Point\u5c06\u83b7\u5f972500\u4e07\u7f8e\u5143\u7684\u524d\u671f\u9884\u4ed8\u6b3e\uff0c\u9ad8\u8fbe1.51\u4ebf\u7f8e\u5143\u7684\u6f5c\u5728\u91cc\u7a0b\u7891\u4ed8\u6b3e\u548c\u7279\u8bb8\u6743\u4f7f\u7528\u8d39 […]<\/p>\n","protected":false},"author":9,"featured_media":340915,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[427],"tags":[513,455,747,925,459],"class_list":["post-340914","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hans","tag-513","tag-455","tag-747","tag-925","tag-459","sectors-life-science-zh-hans","locations-china-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans","exchange-nyse-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/340914","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=340914"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/340914\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/340915"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=340914"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=340914"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=340914"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}