{"id":348774,"date":"2020-09-07T22:42:40","date_gmt":"2020-09-08T05:42:40","guid":{"rendered":"https:\/\/nai500.com\/?p=348774"},"modified":"2020-09-07T22:42:40","modified_gmt":"2020-09-08T05:42:40","slug":"%e7%a6%8f%e6%b3%b0%e5%88%b6%e8%8d%af-%e5%9b%8a%e8%82%bf%e6%80%a7%e7%ba%a4%e7%bb%b4%e5%8c%96%e8%8d%af%e7%89%a9-trikafta","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2020\/09\/%e7%a6%8f%e6%b3%b0%e5%88%b6%e8%8d%af-%e5%9b%8a%e8%82%bf%e6%80%a7%e7%ba%a4%e7%bb%b4%e5%8c%96%e8%8d%af%e7%89%a9-trikafta\/","title":{"rendered":"\u798f\u6cf0\u5236\u836f\u8fd9\u53ea\u80a1\u7968\u53ef\u4ee5\u4e70\u5165\u5417\uff1f"},"content":{"rendered":"

2020\u5e74\u75ab\u60c5\u5f15\u53d1\u7684\u5e02\u573a\u6ce2\u52a8\u662f\u4e0a\u5e02\u516c\u53f8\u4f18\u8d28\u4e0e\u5426\u7684\u8bd5\u91d1\u77f3\uff1a\u6709\u7684\u516c\u53f8\u8f70\u7136\u5d29\u584c\uff0c\u6709\u7684\u516c\u53f8\u62a4\u57ce\u5899\u7684\u575a\u56fa\u5ea6\u53cd\u800c\u5728\u5371\u673a\u4e2d\u5f97\u5230\u4e86\u9a8c\u8bc1\uff0c\u751f\u7269\u5236\u836f\u516c\u53f8\u798f\u6cf0\u5236\u836fVertex Pharmaceuticals\uff08NASDAQ: VRTX\uff09<\/a>\u5c31\u662f\u8fd9\u6837\u7684\u4e00\u5bb6\u516c\u53f8\u3002<\/p>\n

\u798f\u6cf0\u5236\u836f\u662f\u4eca\u5e74\u4ee5\u6765\u6807\u666e500\u6307\u6570\u5f53\u4e2d\u8868\u73b0\u6700\u597d\u768410\u53ea\u533b\u836f\u80a1\u4e4b\u4e00\uff0c\u867d\u7136\u73b0\u5728\u7684\u4f30\u503c\u6c34\u5e73\u4e0d\u4f4e\u2014\u2014\u622a\u81f39\u67083\u65e5\u7684\u80a1\u4ef7\u62a5$269\uff0c\u5e02\u76c8\u7387\u8d85\u8fc734\u2014\u2014\u4f46\u7269\u6709\u6240\u503c\u3002\u516c\u53f8\u5728\u56ca\u80bf\u6027\u7ea4\u7ef4\u5316\uff08CF\uff09\u6cbb\u7597\u9886\u57df\u5360\u636e\u4e3b\u5bfc\u5730\u4f4d\uff0c\u5728\u7814\u836f\u7269\u524d\u666f\u53ef\u671f\uff0c\u53e0\u52a0\u8fc7\u5f80\u7a33\u5065\u7684\u76c8\u5229\u589e\u957f\uff0c\u798f\u6cf0\u5236\u836f\u662f\u4e00\u53ea\u4e0d\u53ef\u4e0d\u6263\u7684\u503c\u5f97\u957f\u7ebf\u6301\u6709\u7684\u4f18\u8d28\u6210\u957f\u80a1\u3002<\/p>\n

\u5bfb\u627e\u4e0b\u4e00\u4e2a\u7279\u65af\u62c9\u548cSpaceX\uff01\u56fd\u9645\u91d1\u878d\u6295\u8d44\u535a\u89c8\u4f1a\uff08GCFF\uff092020\u5e74\u7ebf\u4e0a\u6295\u8d44\u4f1a\u8bae\u2014\u2014\u6295\u8d44\u521b\u65b0\u9886\u57df\u5c06\u4e8e2020\u5e749\u670810\u65e5\u6b63\u5f0f\u4e3e\u884c\uff0c\u4f1a\u4e0a\u5c06\u5411\u5317\u7f8e\u5730\u533a\u7684\u534e\u4eba\u6295\u8d44\u8005\u4ecb\u7ecd\u79d1\u6280\u3001\u6e05\u6d01\u6280\u672f\u3001\u533b\u7597\u4fdd\u5065\u3001\u751f\u547d\u79d1\u5b66\u3001\u91d1\u878d\u79d1\u6280\u548c\u5927\u9ebb\u7b49\u5feb\u901f\u589e\u957f\u521b\u65b0\u9886\u57df\u4e2d\u6700\u65b0\u7684\u6295\u8d44\u673a\u4f1a\u3002\u672c\u6b21\u7ebf\u4e0a\u5927\u4f1a\u7531\u5317\u7f8e\u6295\u8d44\u8baf\u606f\u6709\u9650\u516c\u53f8\u4e3b\u529e\uff0c\u91cd\u70b9\u63a8\u4ecb12\u4e2a\u4e0a\u5e02\u548c\u79c1\u4eba\u516c\u53f8\u7684\u6295\u8d44\u673a\u4f1a\uff0c\u5e76\u63d0\u4f9b\u82f1\u8bed\u548c\u666e\u901a\u8bdd\u540c\u4f20\u670d\u52a1\u3002<\/strong><\/p>\n

GCFF 2020\u5e74\u7ebf\u4e0a\u6295\u8d44\u4f1a\u8bae\u2014\u2014\u6295\u8d44\u521b\u65b0\u9886\u57df\u514d\u8d39\u6ce8\u518c\uff0c\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\u5e76\u6ce8\u518c\u8bf7\u70b9\u51fb\u4ee5\u4e0b\u94fe\u63a5\uff1a<\/strong>https:\/\/gcff-sep-2020.eventbrite.ca<\/strong><\/a><\/p>\n

2019\u5e7410\u6708\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\u4e86\u798f\u6cf0\u5236\u836f\u7684\u91cd\u78c5\u836f\u2014\u2014\u56ca\u80bf\u6027\u7ea4\u7ef4\u5316\u836f\u7269Trikafta\u3002\u8fd9\u6b3e\u65b0\u836f\u6b64\u540e\u6210\u4e3a\u4e86\u8be5\u80a1\u4e0a\u6da8\u7684\u91cd\u8981\u50ac\u5316\u5242\u3002Trikafta\u83b7\u6279\u6cbb\u7597\u5927\u7ea690%\u7684\u56ca\u80bf\u6027\u7ea4\u7ef4\u5316\u60a3\u8005\uff0c\u800c\u5168\u7403\u8303\u56f4\u5185\u7684\u56ca\u80bf\u6027\u7ea4\u7ef4\u5316\u60a3\u8005\u4eba\u6570\u4f30\u8ba1\u8d85\u8fc770,000\u4eba\u3002<\/p>\n

Allied Market Research\u7684\u6570\u636e\u663e\u793a\uff0c2019\u5e74\u56ca\u80bf\u6027\u7ea4\u7ef4\u5316\u6cbb\u7597\u5e02\u573a\u7684\u89c4\u6a21\u4e3a$46\u4ebf\uff0c\u52302026\u5e74\u6709\u671b\u5347\u81f3$93\u4ebf\u3002\u9274\u4e8e\u798f\u6cf0\u5236\u836f\u5728\u8fd9\u4e00\u9886\u57df\u7684\u9886\u5148\u5730\u4f4d\uff0c\u90e8\u5206\u5206\u6790\u5e08\u9884\u8ba1\u8be5\u516c\u53f8\u672a\u67655\u5e74\u7684\u5e74\u5747\u76c8\u5229\u589e\u901f\u5c06\u63a5\u8fd125%\u3002<\/p>\n

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1991\u5e74\u9996\u6b21\u516c\u5f00\u53d1\u884c\uff08IPO\uff09\u4ee5\u6765\uff0c\u798f\u6cf0\u5236\u836f\u7684\u80a1\u4ef7\u51fa\u73b0\u4e86\u7206\u70b8\u5f0f\u4e0a\u6da8\u3002\u8be5\u516c\u53f8\u66fe\u57282000\u5e748\u670824\u65e5\u8fdb\u884c\u8fc7\u4e00\u6b211\u62c62\u7684\u80a1\u7968\u5206\u62c6\u3002<\/p>\n

\"\"<\/p>\n

\u6211\u4eec\u5047\u8bbe\u4f60\u57282000\u5e74\u62c6\u80a1\u540e\u4e70\u5165$5,000\u7684\u798f\u6cf0\u5236\u836f\u80a1\u7968\u3002\u6309\u7167\u5f53\u65f6\u5927\u7ea6$80\u7684\u80a1\u4ef7\u8ba1\u7b97\uff0c\u5927\u6982\u53ef\u4ee5\u4e70\u516563\u53ea\u80a1\u7968\u3002\u4eca\u5929\uff0c\u8fd9\u7b14\u6295\u8d44\u7684\u91d1\u989d\u7ea6\u4e3a$16,930\u3002<\/p>\n

\u798f\u6cf0\u5236\u836f\u7684\u80a1\u4ef7\u8fc7\u53bb1\u5e74\u4e0a\u6da8\u7ea650%\uff0c\u4eca\u5e74\u8fc4\u4eca\u4e0a\u6da8\u8d85\u8fc722%\uff0c\u540c\u671f\u6807\u666e500\u6307\u6570\u4e0a\u6da87%\u3002<\/p>\n

\u56ca\u80bf\u6027\u7ea4\u7ef4\u5316\u5e02\u573a\u53ca\u5176\u4ed6<\/h2>\n

\u798f\u6cf0\u5236\u836f2019\u5e74\u7684\u4e1a\u7ee9\u53ef\u5708\u53ef\u70b9\uff1a\u6536\u5165\u540c\u6bd4\u589e\u957f32%\uff0c\u73b0\u91d1\u589e\u52a0$6.00\u4ebf\u81f3$38\u4ebf\u3002\u6b64\u5916\uff0c\u516c\u53f82020\u5e74\u4e00\u5b63\u5ea6\uff08\u622a\u81f33\u670831\u65e5\uff09\u7684\u6536\u5165\u540c\u6bd4\u589e\u957f77%\u81f3$15.15\u4ebf\uff0c\u6536\u5165\u7684\u66b4\u589e\u5f97\u76ca\u4e8eTrikafta\u7684\u5de8\u5927\u6210\u529f\u3002\u5728\u7f8e\u4e0a\u5e02\u4ee5\u6765\uff0c\u8be5\u65b0\u836f\u6cbb\u7597\u4e86\u8d85\u8fc718,000\u540d\u60a3\u8005\uff0c\u76c8\u5229$8.95\u4ebf\u3002<\/p>\n

\u4e0d\u8fc7\uff0c\u65b0\u51a0\u75ab\u60c5\u7ed9\u516c\u53f8\u4e8c\u5b63\u5ea6\u7684\u4e1a\u7ee9\u6253\u4e0a\u4e86\u4e00\u4e2a\u5927\u5927\u7684\u95ee\u53f7\u3002\u53ef\u559c\u7684\u662f\uff0c\u798f\u6cf0\u5236\u836f7\u670830\u65e5\u53d1\u5e03\u7684\u4e8c\u5b63\u62a5\u663e\u793a\uff0c\u6536\u5165\u540c\u6bd4\u589e\u957f62%\u81f3$15.24\u4ebf\uff0c\u6309\u7167\u7f8e\u56fd\u516c\u8ba4\u4f1a\u8ba1\u51c6\u5219\uff08GAAP\uff09\u6838\u7b97\u7684\u51c0\u5229\u6da6\u589e\u957f213%\u3002<\/p>\n

\u9664\u4e86Trikafta\u2014\u2014\u4e8c\u5b63\u5ea6\u8d21\u732e$9.18\u4ebf\u7684\u6536\u5165\u2014\u2014\u798f\u6cf0\u5236\u836f\u5176\u4ed6\u7684\u56ca\u80bf\u6027\u7ea4\u7ef4\u5316\u836f\u7269\u4e5f\u662f\u91cd\u8981\u7684\u6536\u5165\u6765\u6e90\u3002Symdeko\/Symkevi\u521b\u6536$1.72\u4ebf\uff0cOrkambi\u521b\u6536$2.32\u4ebf\uff0cKalydeco $2.03\u4ebf\u3002\u4e0d\u8fc7\uff0c\u7531\u4e8eTrikafta\u5728\u7f8e\u4e0a\u5e02\uff0c\u8fd9\u4e9b\u836f\u7269Q2\u7684\u9500\u552e\u989d\u76f8\u6bd4\u4e0a\u5e74\u540c\u671f\u51fa\u73b0\u4e86\u4e0b\u6ed1\u3002<\/p>\n

\u6b64\u5916\uff0c\u798f\u6cf0\u5236\u836f\u6b63\u5728\u7814\u53d1\u7684\u4e00\u4e9b\u5019\u9009\u836f\u7269\u4e5f\u975e\u5e38\u503c\u5f97\u671f\u5f85\u3002\u6bd4\u5982\u8bf4\uff0c\u8be5\u516c\u53f8\u6b63\u5728\u4e0eCRISPR Therapeutics AG\uff08NASDAQ: CRSP\uff09<\/a>\u8054\u5408\u7814\u53d1\u4e00\u79cd\u5b9e\u9a8c\u6027\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\uff0c\u9488\u5bf9\u7684\u662f\u60a3\u6709\u4e25\u91cd\u9570\u72b6\u7ec6\u80de\u75c5\uff08SCD\uff09\u4ee5\u53ca\u4e00\u79cd\u540d\u4e3a\u8f93\u8840\u4f9d\u8d56\u6027\u03b2\u5730\u4e2d\u6d77\u8d2b\u8840\uff08TDT\uff09\u7684\u7f55\u89c1\u9057\u4f20\u75c5\u7684\u60a3\u8005\u3002\u53e6\u5916\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u4e00\u9879\u6cbb\u7597\u4e00\u578b\u7cd6\u5c3f\u75c5\u7684\u7ec6\u80de\u7597\u6cd5\u6b63\u5904\u4e8e\u7814\u7a76\u7684\u65e9\u671f\u9636\u6bb5\u3002\u798f\u6cf0\u5236\u836f\u8ba1\u5212\u57282020\u5e74\u672b\u5411FDA\u63d0\u4ea4\u8be5\u6f5c\u5728\u7597\u6cd5\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\uff08IND\uff09\u7533\u8bf7\u3002<\/p>\n

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