{"id":356028,"date":"2020-11-03T15:34:21","date_gmt":"2020-11-03T23:34:21","guid":{"rendered":"https:\/\/nai500.com\/?p=356028"},"modified":"2020-11-03T15:34:21","modified_gmt":"2020-11-03T23:34:21","slug":"%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1-crispr","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2020\/11\/%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1-crispr\/","title":{"rendered":"\u8fd1\u671f\u5229\u7a7a\u88ad\u6765\uff0c\u4f46\u57fa\u56e0\u7f16\u8f91\u80a1CRISPR\u5c06\u8fce\u6765\u7206\u53d1\uff01"},"content":{"rendered":"

10\u670821\u65e5\uff0c\u57fa\u56e0\u7f16\u8f91\u80a1CRISPR Therapeutics AG\uff08NASDAQ: CRSP\uff09<\/a>\u62ab\u9732\u4e00\u6761\u5229\u7a7a\u6d88\u606f\uff1a\u672c\u6708\u65e9\u4e9b\u65f6\u5019\uff0c\u53c2\u4e0eCarbon\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08\u9002\u5e94\u75c7\u4e3a\u590d\u53d1\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff09\u7684\u4e00\u540d\u60a3\u8005\u610f\u5916\u6b7b\u4ea1\u3002\u4e0d\u8fc7\uff0c\u8fd9\u4e00\u4e0d\u5e78\u7684\u6d88\u606f\u5e76\u4e0d\u4f1a\u51cf\u5f31\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u548c\u7ec6\u80de\u7597\u6cd5\u7ed9\u8be5\u516c\u53f8\u5e26\u6765\u7684\u5de8\u5927\u6f5c\u529b\uff0c\u4e34\u5e8a\u8bd5\u9a8c\u4e5f\u4e0d\u4f1a\u53d7\u6b64\u5f71\u54cd\u3002\u76f8\u53cd\uff0c\u6709\u4e86\u8bd5\u9a8c\u7684\u521d\u671f\u7ed3\u679c\uff0cCRISPR\u73b0\u5728\u624b\u91cc\u5df2\u7ecf\u638c\u63e1\u4e86\u4e24\u5927\u6210\u679c\u3002<\/p>\n

\u9996\u5148\uff0c\u516c\u53f8\u8fd9\u4e00\u80bf\u7624\u5728\u7814\u836f\u7269\u9879\u76ee\u83b7\u5f97\u4e86\u4e34\u5e8a\u6982\u5ff5\u9a8c\u8bc1\u3002\u867d\u7136\u6709\u4e00\u540d\u60a3\u8005\u6b7b\u4ea1\uff0c\u4f46\u8bd5\u9a8c\u4e2d\u5176\u4ed6\u60a3\u8005\u7684\u6cbb\u7597\u6548\u679c\u79ef\u6781\u3002\u5176\u6b21\uff0c\u516c\u53f8\u7684\u7ec6\u80de\u7597\u6cd5\u5236\u9020\u65b9\u6cd5\u5728\u73b0\u5b9e\u4e16\u754c\u4e2d\u5f97\u5230\u4e86\u9a8c\u8bc1\u3002\u8fd9\u4e24\u5927\u6210\u679c\u900f\u9732\u7ed9\u6295\u8d44\u8005\u7684\u4e00\u4e2a\u4fe1\u606f\u662f\uff0c\u73b0\u5728\u5e94\u8be5\u9022\u4f4e\u4e70\u5165\u5e76\u957f\u7ebf\u6301\u6709\u3002<\/p>\n

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CRISPR\u7ec6\u80de\u7597\u6cd5CTX110\u7684\u6548\u529b\u548c\u5b89\u5168\u6027<\/h2>\n

CRISPR\u7684\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u7ec6\u80de\u7597\u6cd5CTX110\u662f\u8be5\u516c\u53f8\u9996\u6b3e\u5b8c\u5168\u6240\u6709\u4e14\u5185\u90e8\u5f00\u53d1\u7684\u80bf\u7624\u836f\u7269\u3002CTX110\u7684\u4e34\u5e8a\u8bd5\u9a8c\u5f53\u4e2d\uff0c11\u540d\u60a3\u8005\u63a5\u53d7\u4e0d\u540c\u5242\u91cf\u7684\u6cbb\u7597\u3002\u7ed3\u679c\u663e\u793a\uff0c\u6700\u4f4e\u5242\u91cf\u7ec4\u7684\u60a3\u8005\u5bf9\u6cbb\u7597\u5e76\u6ca1\u6709\u4ea7\u751f\u53cd\u5e94\uff0c\u4f46\u4e5f\u6ca1\u6709\u51fa\u73b0\u610f\u6599\u4e4b\u5916\u7684\u4e0d\u826f\u53cd\u5e94\u3002\u4e0d\u5e78\u7684\u662f\uff0c\u6700\u9ad8\u5242\u91cf\u7ec4\u76841\u540d\u60a3\u8005\u6b7b\u4ea1\u3002<\/p>\n

\u6839\u636eCRISPR\u7684\u62a5\u544a\uff0c\u8be5\u60a3\u8005\u51fa\u73b0\u4e86\u75b1\u75b9\u75c5\u6bd2\u611f\u67d3\u7684\u91cd\u65b0\u6fc0\u6d3b\uff0c\u968f\u540e\u5f15\u53d1\u8111\u708e\u3002\u4e0d\u8fc7\uff0c\u6b21\u9ad8\u5242\u91cf\u7ec4\u76848\u540d\u60a3\u8005\u5f53\u4e2d\uff0c4\u4eba\u57283\u4e2a\u6708\u540e\u5bf9\u6cbb\u7597\u4ea7\u751f\u4e86\u5b8c\u5168\u53cd\u5e94\uff0c\u751a\u81f3\u67091\u540d\u60a3\u8005\u53ef\u68c0\u6d4b\u51fa\u7684\u764c\u7ec6\u80de\u6570\u91cf\u51fa\u73b0\u4e86\u5927\u5e45\u4e0b\u964d\u3002\u9274\u4e8e\u6240\u6709\u8fd9\u4e9b\u60a3\u8005\u6b64\u524d\u90fd\u60a3\u6709\u590d\u53d1\u6216\u96be\u6cbb\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff0c\u56e0\u6b64\u8fd9\u4e00\u7ed3\u679c\u975e\u5e38\u79ef\u6781\u3002\u7136\u800c\uff0c\u60a3\u8005\u6b7b\u4ea1\u4ecd\u5f15\u53d1\u4e86\u6295\u8d44\u8005\u7684\u62c5\u5fe7\uff0c\u4ed6\u4eec\u62c5\u5fc3CTX110\u53ef\u80fd\u4f1a\u5bf9\u514d\u75ab\u529f\u80fd\u4e0d\u5168\u4e2a\u4f53\u4f1a\u9020\u6210\u591a\u5927\u7684\u98ce\u9669\uff0c\u8fdb\u800c\u6709\u53ef\u80fd\u6700\u7ec8\u963b\u788d\u8be5\u7597\u6cd5\u7684\u83b7\u6279\u3002<\/p>\n

CRISPR\u7684\u4e3b\u8981\u613f\u666f\u662f\u5927\u89c4\u6a21\u751f\u4ea7\u9002\u7528\u4e8e\u4efb\u4f55\u4eba\u7684\u7ec6\u80de\u7597\u6cd5\u3002\u4e0d\u8fc7\uff0c\u5b9e\u73b0\u8fd9\u4e00\u76ee\u6807\u7684\u4e00\u4e2a\u4e3b\u8981\u969c\u788d\u662f\u7ec6\u80de\u7597\u6cd5\u901a\u5e38\u90fd\u751f\u4ea7\u81ea\u4eba\u7c7b\u4f9b\u4f53\u63d0\u53d6\u7684\u7ec6\u80de\u3002\u4ece\u4f9b\u4f53\u4e2d\u63d0\u53d6\u51fa\u6765\u540e\uff0c\u8fd9\u4e9b\u7ec6\u80de\u5c06\u88ab\u57fa\u56e0\u7f16\u8f91\u5e76\u6210\u4e3a\u5177\u5907\u9884\u671f\u6cbb\u7597\u4f5c\u7528\u7684\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\uff0c\u63a5\u7740\u5c06\u88ab\u6ce8\u5165\u60a3\u8005\u4f53\u5185\u3002\u5982\u679c\u4f9b\u4f53\u7684\u7ec6\u80de\u4e0e\u53d7\u4f53\u65e0\u6cd5\u83b7\u5f97\u5b8c\u7f8e\u5339\u914d\uff0c\u6cbb\u7597\u7ec6\u80de\u6709\u53ef\u80fd\u4f1a\u653b\u51fb\u60a3\u8005\u7684\u7ec6\u80de\uff0c\u5f15\u53d1\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\uff08GvHD\uff09\uff0c\u751a\u81f3\u5bfc\u81f4\u60a3\u8005\u6b7b\u4ea1\u3002<\/p>\n

\u9664\u975e\u6709\u65b0\u7684\u521b\u65b0\u89e3\u51b3\u7ec6\u80de\u7597\u6cd5\u7684\u5b89\u5168\u6027\u95ee\u9898\uff0c\u5426\u5219\u5065\u5eb7\u4f9b\u4f53\u7684\u7ec6\u80de\u4e0d\u53ef\u80fd\u5236\u6210\u80bf\u7624\u7ec6\u80de\u7597\u6cd5\u3002\u56e0\u6b64\uff0c\u5f88\u591a\u7ec6\u80de\u7597\u6cd5\u90fd\u9700\u8981\u60a3\u8005\u6350\u8d60\u4ed6\u4eec\u81ea\u5df1\u7684\u7ec6\u80de\u5e76\u5236\u6210\u6cbb\u7597\u4ea7\u54c1\uff0c\u4ee5\u6b64\u9884\u9632\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\u7684\u98ce\u9669\u3002\u5f88\u91cd\u8981\u7684\u4e00\u70b9\u662f\uff0c\u6b64\u6b21\u8bd5\u9a8c\u7684\u60a3\u8005\uff08\u5305\u62ec\u90a3\u540d\u6b7b\u4ea1\u60a3\u8005\uff09\u90fd\u6ca1\u6709\u51fa\u73b0\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\u7684\u75c7\u72b6\u3002\u8fd9\u610f\u5473\u7740\u8be5\u516c\u53f8\u7684\u5236\u9020\u521b\u65b0\u6210\u529f\u751f\u4ea7\u51fa\u4e86\u4f7f\u7528\u5065\u5eb7\u4f9b\u4f53\u7ec6\u80de\u7684\u5b89\u5168\u7684\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\u3002\u8fd9\u4e00\u6210\u679c\u5bf9\u4e8eCRISPR\u7684\u672a\u6765\u6709\u591a\u91cd\u8981\u4e0d\u8a00\u800c\u55bb\u3002<\/p>\n

\u4f7f\u7528\u60a3\u8005\u81ea\u8eab\u7ec6\u80de\u751f\u4ea7\u7ec6\u80de\u7597\u6cd5\u65e0\u6cd5\u5b9e\u73b0\u5927\u89c4\u6a21\u751f\u4ea7\u3002\u9664\u4e86\u9700\u8981\u8017\u8d39\u5927\u91cf\u7684\u65f6\u95f4\uff0c\u6210\u672c\u4e5f\u4f1a\u975e\u5e38\u9ad8\uff0c\u4f46CRISPR\u7684\u65b9\u6cd5\u5c31\u8981\u7b80\u4fbf\u5f88\u591a\uff0c\u5e76\u4e14\u6211\u4eec\u671f\u5f85\u5b89\u5168\u6027\u4e5f\u4e0d\u4f1a\u51cf\u5206\u3002<\/p>\n

\u63a5\u4e0b\u6765\u5462\uff1f<\/h2>\n

\u7b80\u5355\u6765\u8bf4\uff0cCTX110\u8bd5\u9a8c\u7684\u521d\u671f\u6570\u636e\u663e\u793a\uff0c\u901a\u8fc7\u975e\u60a3\u8005\u4f9b\u4f53\u5927\u89c4\u6a21\u751f\u4ea7\u6709\u6548\u7684\u7ec6\u80de\u7597\u6cd5\u6210\u4e3a\u4e86\u53ef\u80fd\uff0c\u8fd9\u4e5f\u4e3a\u8be5\u516c\u53f8\u672a\u6765\u5f00\u53d1\u9488\u5bf9\u5176\u4ed6\u75be\u75c5\u7684\u7ec6\u80de\u7597\u6cd5\u94fa\u5e73\u4e86\u9053\u8def\u3002\u6b64\u5916\uff0c\u672a\u6765\u901a\u7528\u578b\u7ec6\u80de\u836f\u7269\u4e5f\u4e0d\u518d\u662f\u9065\u4e0d\u53ef\u53ca\u7684\u76ee\u6807\u3002\u672a\u6765\uff0cCRISPR\u7684\u6838\u5fc3\u613f\u666f\u4e0d\u518d\u662f\u969c\u788d\uff0c\u63a5\u4e0b\u6765\u9700\u8981\u5b8c\u6210\u7684\u662f\u8981\u627e\u5230\u5177\u5907\u6cbb\u7597\u6548\u679c\u7684\u5019\u9009\u7ec6\u80de\u7597\u6cd5\u3002<\/p>\n

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10\u670821\u65e5\uff0c\u57fa\u56e0\u7f16\u8f91\u80a1CRISPR Therapeutics AG\uff08NASDAQ: CRSP\uff09\u62ab\u9732\u4e00\u6761\u5229\u7a7a\u6d88 […]<\/p>\n","protected":false},"author":27,"featured_media":356029,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1521,430],"tags":[455,925,459],"class_list":["post-356028","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1521","category-trends-strategies-zh-hans","tag-455","tag-925","tag-459","sectors-life-science-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/356028","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=356028"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/356028\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/356029"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=356028"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=356028"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=356028"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}