{"id":416806,"date":"2022-03-08T22:23:34","date_gmt":"2022-03-09T06:23:34","guid":{"rendered":"https:\/\/nai500.com\/?p=416806"},"modified":"2022-03-08T22:23:34","modified_gmt":"2022-03-09T06:23:34","slug":"%e5%88%86%e6%9e%90%e5%b8%88%e4%bb%ac%e6%8e%a8%e8%8d%90%e8%bf%99%e4%ba%9b%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1%e7%a5%a8","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2022\/03\/%e5%88%86%e6%9e%90%e5%b8%88%e4%bb%ac%e6%8e%a8%e8%8d%90%e8%bf%99%e4%ba%9b%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1%e7%a5%a8\/","title":{"rendered":"\u5206\u6790\u5e08\u4eec\u63a8\u8350\u8fd9\u4e9b\u57fa\u56e0\u7f16\u8f91\u80a1\u7968"},"content":{"rendered":"<p>\u57fa\u56e0\u6cbb\u7597\u548c\u57fa\u56e0\u7f16\u8f91\u662f\u73b0\u4ee3\u751f\u7269\u79d1\u6280\u7684\u6700\u524d\u6cbf\u3002\u57fa\u56e0\u6cbb\u7597\u662f\u901a\u8fc7\u5728\u7ec6\u80de\u6c34\u5e73\u4e0a\u5f15\u5165\u9057\u4f20\u7269\u8d28\u6765\u7ea0\u6b63\u9057\u4f20\u5f02\u5e38\u3002\u57fa\u56e0\u7f16\u8f91\u5c06\u79d1\u5b66\u63d0\u5347\u5230\u4e00\u4e2a\u65b0\u7684\u6c34\u5e73\uff0c\u5bfb\u6c42\u76f4\u63a5\u6539\u53d8\u57fa\u56e0\u7ec4\u672c\u8eab\u4f5c\u4e3a\u4e00\u79cd\u6cbb\u7597\u65b9\u6cd5\u3002\u5927\u591a\u6570\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u5728\u6700\u8fd1\u51e0\u4e2a\u6708\u53d7\u5230\u4e86\u91cd\u521b\uff0c\u4f46Fior Markets\u7684\u5206\u6790\u5e08\u4ecd\u7136\u9884\u8ba1\u5168\u7403\u57fa\u56e0\u7ec4\u7f16\u8f91\u5e02\u573a\u5c06\u4ece2020\u5e74\u768442\u4ebf\u7f8e\u5143\u589e\u957f\u52302028\u5e74\u7684130\u4ebf\u7f8e\u5143\u3002\u6839\u636e\u7f8e\u56fd\u94f6\u884c\u7684\u6570\u636e\uff0c\u8fd9\u91cc\u6709\u51e0\u53ea\u6700\u503c\u5f97\u8d2d\u4e70\u7684\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u3002<\/p>\n<h2>CRISPR Therapeutics AG\uff08<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=CPSP\">CRSP<\/a>\uff09<\/h2>\n<p>CRISPR Therapeutics\u662f\u4e00\u5bb6\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u4f7f\u7528\u57fa\u56e0\u7f16\u8f91\u5de5\u5177CRISPR-Cas9\u6cbb\u7597\u8840\u7ea2\u86cb\u767d\u75c5\uff0c\u4ece\u800c\u6cbb\u7597\u8840\u6db2\u75be\u75c5\u548c\u764c\u75c7\u3002CRISPR \u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u62e5\u6709\u4e09\u79cd 100% \u62e5\u6709\u7684\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\uff0c\u5e76\u6b63\u5728\u4e0e\u5408\u4f5c\u4f19\u4f34 Vertex Pharmaceuticals Inc. (VRTX) \u548c ViaCyte Inc. \u5171\u540c\u5f00\u53d1\u53e6\u5916\u4e24\u79cd\u7597\u6cd5\u3002 CRSP\u80a1\u4ef7\u5728\u8fc7\u53bb\u516d\u4e2a\u6708\u4e2d\u4e0b\u8dcc\u4e8650%\u4ee5\u4e0a\uff0c\u4f46\u5206\u6790\u5e08Geoff Meacham\u8868\u793a\uff0c\u52302022\u5e74\u5e95CTX001\u53ef\u80fd\u63d0\u4ea4\u7684\u76d1\u7ba1\u6587\u4ef6\u7684\u66f4\u65b0\u53ef\u80fd\u4f1a\u63a8\u52a8CRISPR\u7684\u4f30\u503c\u91cd\u4f30\u3002\u7f8e\u56fd\u94f6\u884c\u5bf9CRSP\u80a1\u7968\u7684\u8bc4\u7ea7\u4e3a &#8220;\u4e70\u5165&#8221;\uff0c\u76ee\u6807\u4ef7\u4e3a150\u7f8e\u5143\uff0c3\u67084\u65e5\u7684\u6536\u76d8\u4ef7\u4e3a54.19\u7f8e\u5143\u3002<\/p>\n<h2>Beam Therapeutics Inc. (<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=BEAM\">BEAM<\/a>)<\/h2>\n<p>Beam Therapeutics\u5229\u7528CRISPR\u6280\u672f\u6539\u53d8\u57fa\u56e0\u7ec4\u4e2d\u7684\u5355\u4e2a\u78b1\u57fa\uff0c\u8fd9\u79cd\u6280\u672f\u53ea\u7834\u574fDNA\u7684\u4e00\u6761\u94fe\uff0c\u5e76\u4e14\u53ef\u80fd\u6709\u66f4\u9ad8\u7684\u7ec6\u80de\u5b58\u6d3b\u7387\u3002\u8be5\u516c\u53f8\u4e13\u6ce8\u4e8e\u8840\u6db2\u75be\u75c5\u548c\u764c\u75c7\u9002\u5e94\u75c7\uff0c\u4f46\u4e5f\u5728\u7814\u7a76\u773c\u775b\u548c\u809d\u810f\u75be\u75c5\u7684\u6cbb\u7597\u3002\u5206\u6790\u5e08Greg Harrison\u8bf4\uff0c\u8be5\u516c\u53f8\u7684BEAM-101\u7597\u6cd5\u6b63\u5728\u5411\u4e34\u5e8a\u7814\u7a76\u9636\u6bb5\u8fc7\u6e21\uff0c\u5e76\u53ef\u80fd\u57282022\u5e74\u4e0b\u534a\u5e74\u63d0\u4ea4BEAM-102\u548cBEAM-201\u7684\u65b0\u836f\u7533\u8bf7\u3002\u7f8e\u56fd\u94f6\u884c\u5bf9BEAM\u80a1\u7968\u7684\u8bc4\u7ea7\u4e3a&#8221;\u4e70\u5165&#8221;\uff0c\u76ee\u6807\u4ef7\u4e3a154\u7f8e\u5143\uff0c\u8be5\u80a13\u67084\u65e5\u6536\u4e8e64.38\u7f8e\u5143\u3002<\/p>\n<h2>Apellis Pharmaceuticals Inc. (<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=APLS\">APLS<\/a>)<\/h2>\n<p>Apellis Pharmaceuticals\u662f\u4e00\u5bb6\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u9488\u5bf9\u514d\u75ab\u7cfb\u7edf\u8865\u4f53\u9014\u5f84\u7684\u6cbb\u7597\uff0c\u589e\u5f3a\u514d\u75ab\u7cfb\u7edf\u6e05\u9664\u53d7\u635f\u7ec6\u80de\u7684\u80fd\u529b\u3002\u8be5\u516c\u53f8\u7684\u4e3b\u8981\u4ea7\u54c1\u662fpegcetacoplan\uff0c\u5df2\u7ecf\u5728\u7f8e\u56fd\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u9635\u53d1\u6027\u591c\u95f4\u8840\u7ea2\u86cb\u767d\u5c3f\u75c7\u5e76\u5904\u4e8e\u6cbb\u7597\u5730\u7406\u840e\u7f29\u7684\u540e\u671f\u5f00\u53d1\u9636\u6bb5\u30022021\u5e746\u6708\uff0cApellis\u5ba3\u5e03\u4e0eBeam Therapeutics\u5f00\u5c55\u65b0\u7684\u5408\u4f5c\uff0c\u5229\u7528\u57fa\u7840\u7f16\u8f91\u6280\u672f\u7814\u7a76\u773c\u775b\u3001\u809d\u810f\u548c\u5927\u8111\u7684\u65b0\u7cbe\u51c6\u7597\u6cd5\u3002\u5206\u6790\u5e08Tazeen Ahmad\u8bf4\uff0c\u6295\u8d44\u8005\u5e94\u671f\u5f85Apellis\u57282022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u63d0\u4ea4\u6cbb\u7597\u5730\u7406\u840e\u7f29\u7684pegcetacoplan\u7684\u65b0\u836f\u7533\u8bf7\uff0c\u5e76\u57282022\u5e74\u5e95\u524d\u83b7\u5f97\u6f5c\u5728\u7684\u76d1\u7ba1\u6279\u51c6\u3002\u7f8e\u56fd\u94f6\u884c\u5bf9APLS\u7684\u8bc4\u7ea7\u4e3a &#8220;\u4e70\u5165&#8221;\uff0c\u76ee\u6807\u4ef7\u4e3a70\u7f8e\u5143\uff0c\u8be5\u516c\u53f83\u67084\u65e5\u6536\u76d8\u4ef7\u4e3a43.51\u7f8e\u5143\u3002<\/p>\n<h2>Graphite Bio Inc. (<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=CRPH\">GRPH<\/a>)<\/h2>\n<p>Graphite Bio\u662f\u4e00\u5bb6\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u516c\u53f8\uff0c\u4ee5GPH-101\u7814\u7a76\u6027\u57fa\u56e0\u7f16\u8f91\u81ea\u4f53\u9020\u8840\u5e72\u7ec6\u80de\u5019\u9009\u7269\u5728\u8840\u7ea2\u86cb\u767d\u75c5\u9886\u57df\u8131\u9896\u800c\u51fa\uff0c\u8be5\u5019\u9009\u7269\u6b63\u5904\u4e8e\u6cbb\u7597\u9570\u72b6\u7ec6\u80de\u75c5\u7684\u65e9\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u3002\u5176\u76ee\u7684\u662f\u7ea0\u6b63\u6f5c\u5728\u7684\u7a81\u53d8\uff0c\u51cf\u5c11\u9570\u72b6\u7ec6\u80de\u7684\u4ea7\u751f\uff0c\u5e76\u4f7f\u7528\u4e00\u79cd\u79f0\u4e3a\u540c\u6e90\u5b9a\u5411\u4fee\u590d\u7684DNA\u4fee\u590d\u8fc7\u7a0b\u6765\u6062\u590d\u6b63\u5e38\u7ec6\u80de\u7684\u4ea7\u751f\u3002Meachim\u8bf4\uff0c\u6295\u8d44\u8005\u53ef\u4ee5\u671f\u5f85\u57282022\u5e74\u5e95\u62162023\u5e74\u521d\u83b7\u5f97GPH-101\u7684\u521d\u6b65\u4e34\u5e8a\u6570\u636e\u3002\u7f8e\u56fd\u94f6\u884c\u5bf9GRPH\u80a1\u7968\u7684\u8bc4\u7ea7\u4e3a&#8221;\u4e70\u5165&#8221;\uff0c\u76ee\u6807\u4ef7\u4e3a30\u7f8e\u5143\uff0c\u8be5\u80a13\u67084\u65e5\u6536\u4e8e8.17\u7f8e\u5143\u3002<\/p>\n<h2>Caribou Biosciences Inc. (<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=CRBU\">CRBU<\/a>)<\/h2>\n<p>Caribou Biosciences\u662f\u4e00\u5bb6\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u764c\u75c7\u7684\u57fa\u56e0\u7f16\u8f91\u7684\u5f02\u4f53\u7ec6\u80de\u7597\u6cd5\u3002\u8be5\u516c\u53f8\u4e8e2021\u5e747\u6708\u5b8c\u6210\u9996\u6b21\u516c\u5f00\u52df\u80a1\u3002Meachim\u8bf4\uff0cCaribou\u4e13\u6709\u7684chRDNA\u57fa\u56e0\u7f16\u8f91\u65b9\u6cd5\u5728\u7597\u6548\u548c\u7279\u5f02\u6027\u65b9\u9762\u53ef\u80fd\u6bd4\u4f20\u7edf\u65b9\u6cd5\u66f4\u6709\u4f18\u52bf\u3002Caribou\u7684\u5173\u952e2022\u5e74\u50ac\u5316\u5242\u5305\u62ecCD-010\u7684\u521d\u59cb1\u671f\u6570\u636e\u4ee5\u53caCB-011\u7684\u65b0\u836f\u7814\u7a76\u7533\u8bf7\u3002\u7f8e\u56fd\u94f6\u884c\u5bf9CRBU\u80a1\u7968\u7684\u8bc4\u7ea7\u4e3a&#8221;\u4e70\u5165&#8221;\uff0c\u76ee\u6807\u4ef7\u4e3a33\u7f8e\u5143\uff0c3\u67084\u65e5\u7684\u6536\u76d8\u4ef7\u4e3a8.93\u7f8e\u5143\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u57fa\u56e0\u6cbb\u7597\u548c\u57fa\u56e0\u7f16\u8f91\u662f\u73b0\u4ee3\u751f\u7269\u79d1\u6280\u7684\u6700\u524d\u6cbf\u3002\u57fa\u56e0\u6cbb\u7597\u662f\u901a\u8fc7\u5728\u7ec6\u80de\u6c34\u5e73\u4e0a\u5f15\u5165\u9057\u4f20\u7269\u8d28\u6765\u7ea0\u6b63\u9057\u4f20\u5f02\u5e38\u3002\u57fa\u56e0\u7f16\u8f91\u5c06\u79d1\u5b66 [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":416807,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[427],"tags":[513,455,747,925],"class_list":["post-416806","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hans","tag-513","tag-455","tag-747","tag-925","sectors-technology-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans","exchange-nyse-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/416806","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=416806"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/416806\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/416807"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=416806"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=416806"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=416806"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}