{"id":450037,"date":"2023-01-22T23:24:41","date_gmt":"2023-01-23T07:24:41","guid":{"rendered":"https:\/\/nai500.com\/?p=450037"},"modified":"2023-01-22T23:24:41","modified_gmt":"2023-01-23T07:24:41","slug":"%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1%e7%a5%a8-bluebird-bio-crispr-therapeutics","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2023\/01\/%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1%e7%a5%a8-bluebird-bio-crispr-therapeutics\/","title":{"rendered":"\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u4e8c\u9009\u4e00\uff0c\u8be5\u9009Bluebird Bio\u8fd8\u662fCRISPR Therapeutics\uff1f"},"content":{"rendered":"

2023\u5e74\uff0c\u8fd9\u4e24\u53ea\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u6709\u671b\u8fce\u6765\u7a81\u7834<\/h2>\n

\u751f\u7269\u79d1\u6280\u516c\u53f8Bluebird bio Inc\uff08NASDAQ:BLUE\uff09<\/a>\u548cCRISPR Therapeutics AG\uff08NASDAQ:CRSP\uff09<\/a>\u4e13\u6ce8\u4e8e\u6cbb\u7597\u7f55\u89c1\u8840\u6db2\u75c5\u548c\u764c\u75c7\u7684\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\uff0c\u5e76\u4e14\u8fd9\u4e24\u53ea\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u7684\u80a1\u4ef72023\u5e74\u6709\u671b\u8fce\u6765\u53cd\u5f39\uff0c\u5176\u4e2dBluebird\u7684\u80a1\u4ef7\u8fc7\u53bb1\u5e74\u4e0b\u8dcc\u8d85\u8fc716%\u4f46\u8fc7\u53bb3\u4e2a\u6708\u4e0a\u6da8\u8d85\u8fc78%\uff0cCRISPR\u7684\u80a1\u4ef7\u8fc7\u53bb1\u5e74\u4e0b\u8dcc\u8d85\u8fc727%\u4f46\u8fc7\u53bb3\u4e2a\u6708\u4e0a\u6da8\u8d85\u8fc78%\u3002<\/p>\n

\u8fd9\u4e24\u5bb6\u516c\u53f8\u5747\u672a\u76c8\u5229\uff0c\u4e0a\u4e00\u5b63\u5ea6\u7684\u5408\u4f5c\u6536\u5165\u5728$10\u4e07\u5de6\u53f3\u3002\u4e0d\u8fc7\uff0cBluebird Bio\u8fd8\u662fCRISPR Therapeutics\u7684\u5728\u7814\u836f\u7269\u524d\u666f\u90fd\u5f88\u4e0d\u9519\u3002\u5982\u679c\u8981\u8bba\u957f\u671f\u6295\u8d44\u4ef7\u503c\uff0c\u8fd9\u4e24\u53ea\u57fa\u56e0\u7f16\u8f91\u751f\u7269\u79d1\u6280\u80a1\u7968\u8c01\u624d\u662f\u66f4\u597d\u7684\u9009\u62e9\uff1f<\/p>\n

\u9009\u62e9Bluebird Bio\u7684\u7406\u7531<\/h2>\n

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\u53bb\u5e748\u6708\uff0cBluebird\u6cbb\u7597\u7f55\u89c1\u9057\u4f20\u8840\u6db2\u75c5\u8f93\u8840\u4f9d\u8d56\u6027\u03b2\u5730\u4e2d\u6d77\u8d2b\u8840\u7684\u4e00\u6b21\u6027\u6cbb\u6108\u7597\u6cd5Zynteglo\uff08\u5b9a\u4ef7$280\u4e07\uff09\u83b7\u5f97FDA\u6279\u51c6\uff0c\u8be5\u516c\u53f8\u672c\u6708\u8868\u793a\u8be5\u836f\u7269\u9884\u8ba1\u5c06\u4ece2023\u5e74\u4e00\u5b63\u5ea6\u8d77\u521b\u9020\u6536\u5165\u3002\u8be5\u516c\u53f8\u7684\u53e6\u4e00\u6b3e\u836f\u7269Skysona\u53bb\u5e749\u6708\u83b7\u6279\u6cbb\u7597\u8111\u80be\u4e0a\u817a\u8111\u767d\u8d28\u8425\u517b\u4e0d\u826f\uff08CALD\uff09\uff0c\u8fd9\u4e5f\u662f\u5168\u7403\u6700\u6602\u8d35\u7684\u836f\u7269\uff08\u5b9a\u4ef7$300\u4e07\uff09\u3002\u867d\u7136\u03b2\u5730\u4e2d\u6d77\u8d2b\u8840\u548cCALD\u7684\u60a3\u8005\u4eba\u6570\u6709\u9650\uff0c\u4f46\u9ad8\u5b9a\u4ef7\u5c06\u6709\u52a9\u4e8e\u8be5\u516c\u53f8\u5b9e\u73b0\u76c8\u4e8f\u5e73\u8861\u3002<\/p>\n

\u6b64\u5916\uff0cBluebird\u7684\u53e6\u4e00\u6b3e\u540e\u671f\u7597\u6cd5\u662f\u6cbb\u7597\u9570\u72b6\u7ec6\u80de\u75c5\uff08SCD\uff09\u7684lovo-cel\uff0c\u8be5\u516c\u53f8\u9884\u8ba12023\u5e74\u4e00\u5b63\u5ea6\u5411\u7f8e\u56fdFDA\u63d0\u4ea4\u8fd9\u4e00\u4e00\u6b21\u6027\u6cbb\u6108\u7597\u6cd5\u7684\u751f\u7269\u5236\u5242\u8bb8\u53ef\u7533\u8bf7\uff08BLA\uff09\u3002<\/p>\n

\u9009\u62e9CRISPR Therapeutics\u7684\u7406\u7531<\/h2>\n

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CRISPR\u7684\u9996\u5e2d\u7597\u6cd5\u662f\u8054\u5408\u798f\u6cf0\u5236\u836fVertex Pharmaceuticals\uff08NASDAQ:VRTX\uff09\u5f00\u53d1\u7684\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5exa-cel\u3002exa-cel\u5b9a\u4ef7\u53ef\u80fd\u4f4e\u4e8e$280\u4e07\uff0c\u540c\u65f6\u8bd5\u9a8c\u7ed3\u679c\u663e\u793a\u5176\u6709\u6548\u6027\u4e5f\u66f4\u597d\uff0c\u56e0\u6b64\u5982\u679c\u8be5\u7597\u6cd5\u4eca\u5e74\u83b7\u5f97FDA\u6279\u51c6\u5c06\u5bf9Zynteglo\u5f62\u6210\u7ade\u4e89\u4f18\u52bf\u3002exa-cel\u7684\u6536\u5165\u5206\u6210CRISPR\u548c\u798f\u6cf0\u5236\u836f\u5404\u536040%\u548c60%\uff0c\u5e76\u4e14\u4e24\u5bb6\u516c\u53f8\u5df2\u7ecf\u5728\u6b27\u6d32\u548c\u82f1\u56fd\u63d0\u4ea4\u4e86\u6279\u51c6\u7533\u8bf7\uff0c\u540c\u65f6\u7f8e\u56fd\u7684\u6eda\u52a8\u7533\u8bf7\u5c06\u57282023\u5e74\u4e00\u5b63\u5ea6\u5e95\u5b8c\u6210\u3002<\/p>\n

\u6700\u540e\uff0c\u76f8\u6bd4Bluebird\uff0cCRISPR\u5728\u7814\u836f\u7269\u7684\u6570\u91cf\u66f4\u591a\uff0c\u79cd\u7c7b\u66f4\u591a\u6837\uff0c\u5176\u4e2dCAR T-\u7ec6\u80de\u57fa\u56e0\u7597\u6cd5CTX110\u5355\u5242\u6cbb\u7597\u96be\u6cbb\u6027\u548c\u590d\u53d1\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u7ed3\u679c\u79ef\u6781\u3002\u53e6\u4e00\u6b3e\u540c\u79cd\u5f02\u4f53CAR T-\u7ec6\u80de\u57fa\u56e0\u7597\u6cd5CTX130\u6cbb\u7597\u590d\u53d1\u6027\u6216\u96be\u6cbb\u6027T\u6216B\u7ec6\u80de\u6076\u6027\u80bf\u7624\u7684\u521d\u671f\u8bd5\u9a8c\u7ed3\u679c\u4e5f\u975e\u5e38\u4e0d\u9519\uff0c\u5177\u5907\u91cd\u78c5\u836f\u7684\u6f5c\u529b\u3002<\/p>\n

\u9009\u62e9\u663e\u800c\u6613\u89c1<\/h2>\n

Bluebird Bio\u5728\u836f\u54c1\u5ba1\u6279\u65b9\u9762\u5df2\u7ecf\u9886\u5148\uff0c\u4f46CRISPR\u51ed\u501f\u5176exa-cel\u7684\u6709\u6548\u6027\uff0c\u66f4\u5145\u88d5\u7684\u73b0\u91d1\u4ee5\u53ca\u66f4\u5e9e\u5927\u7684\u5728\u7814\u836f\u7269\uff0c\u957f\u671f\u6f5c\u529b\u66f4\u5927\u3002\u6b64\u5916\uff0cCRISPR\u5728\u5e76\u8d2d\u6d88\u606f\u65b9\u9762\u4e5f\u66f4\u591a\u88ab\u63d0\u53ca\uff0c\u8fd9\u5bf9\u73b0\u6709\u80a1\u4e1c\u4e5f\u662f\u4e00\u4e2a\u5de8\u5927\u7684\u6f5c\u5728\u5229\u597d\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

2023\u5e74\uff0c\u8fd9\u4e24\u53ea\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u6709\u671b\u8fce\u6765\u7a81\u7834 \u751f\u7269\u79d1\u6280\u516c\u53f8Bluebird bio Inc\uff08NASDAQ:BLU […]<\/p>\n","protected":false},"author":27,"featured_media":448946,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1521,430],"tags":[455,747,925,459],"class_list":["post-450037","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1521","category-trends-strategies-zh-hans","tag-455","tag-747","tag-925","tag-459","sectors-life-science-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/450037","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=450037"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/450037\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/448946"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=450037"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=450037"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=450037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}