CRISPR Therapeutics AG\uff08NASDAQ:CRSP\uff09<\/a>\u7684\u957f\u671f\u6295\u8d44\u4ef7\u503c\u53ef\u80fd\u66f4\u5927\u3002\u8fd9\u53ea\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u7684\u4ef7\u683c\u4eca\u5e74\u4e0a\u6da8\u8d85\u8fc717%\uff0c\u4f46\u8fc7\u53bb12\u4e2a\u6708\u4f9d\u7136\u4e0b\u8dcc\u8d85\u8fc720%\u3002<\/p>\nCRISPR\u80a1\u7968\u4e3a\u4ec0\u4e48\u9002\u5408\u957f\u7ebf\u6295\u8d44\uff1f\u6709\u4ee5\u4e0b3\u4e2a\u7406\u7531\uff1a<\/p>\n
1. exa-cel\u4e00\u65e6\u83b7\u6279\uff0cCRISPR\u4e5f\u5c06\u53d7\u76ca<\/h2>\n
\u8fd9\u4e00\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\u5982\u679c\u83b7\u5f97\u6279\u51c6\uff0cCRISPR\u5c06\u83b7\u5f9740%\u7684\u6536\u5165\u5206\u6210\uff0c\u8fd9\u53cd\u8fc7\u6765\u53ef\u4ee5\u4e3a\u8fd9\u5bb6\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u79d1\u6280\u516c\u53f8\u5176\u4ed6\u5728\u7814\u836f\u7269\u7684\u5f00\u53d1\u63d0\u4f9b\u8d44\u91d1\u652f\u6301\u3002\u53bb\u5e7412\u6708\uff0cExa-cel\u5728\u6b27\u76df\u548c\u82f1\u56fd\u7684\u7533\u8bf7\u83b7\u5f97\u786e\u8ba4\uff0c\u798f\u6cf0\u5236\u836f\u548cCRISPR\u9884\u8ba1\u7f8e\u56fd\u7684\u751f\u7269\u5236\u5242\u8bb8\u53ef\u7533\u8bf7\uff08BLA\uff09\u5c06\u5728\u8fd9\u4e2a\u5b63\u5ea6\u5b8c\u6210\u3002<\/p>\n
\u6211\u4eec\u4e0d\u80fd\u4fdd\u8bc1FDA\u4e00\u5b9a\u4f1a\u6279\u51c6exa-cel\uff0c\u4f46\u8be5\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\u7684\u4e09\u671f\u8bd5\u9a8c\u2014\u2014\u6cbb\u7597SCD\u7684CLIMB-121\u7814\u7a76\u4ee5\u53ca\u6cbb\u7597TDT\u7684CLIMB-111\u7814\u7a76\u2014\u2014\u7684\u7ed3\u679c\u90fd\u975e\u5e38\u4e0d\u9519\u3002\u5b98\u65b9\u6570\u636e\u663e\u793a\uff0c\u7f8e\u56fdTDT\u548cSCD\u7684\u60a3\u8005\u4eba\u6570\u5206\u522b\u4e0d\u52305000\u4eba\u548c\u5927\u7ea610\u4e07\u4eba\uff0c\u4f46exa-cel\u7684\u5b9a\u4ef7\u6216\u5bf9\u6807Bluebird bio Inc\uff08NASDAQ:BLUE\uff09\u7684TDT\u57fa\u56e0\u7597\u6cd5Zynteglo\uff08$280\u4e07\uff09\uff0c\u867d\u7136\u6602\u8d35\u4f46\u6709\u83b7\u5229\u6f5c\u529b\uff0c\u56e0\u6b64\u4fdd\u9669\u516c\u53f8\u53ef\u80fd\u613f\u610f\u627f\u4fdd\u3002<\/p>\n
2. CRISPR\u7684\u5176\u4ed6\u5728\u7814\u836f\u7269\u524d\u666f\u53ef\u671f<\/h2>\n
CRISPR\u62e5\u670922\u4e2a\u5728\u7814\u836f\u7269\uff0c\u867d\u7136\u5f00\u53d1\u8fdb\u5ea6\u90fd\u4e0d\u53caexa-cel\uff0c\u4f46\u6709\u4e9b\u5df2\u7ecf\u5728\u521d\u671f\u8bd5\u9a8c\u4e2d\u5c55\u73b0\u51fa\u6f5c\u529b\u3002\u6bd4\u5982\u8bf4\uff0c\u91c7\u7528\u540c\u79cd\u5f02\u4f53CRISPR\/Cas9\u57fa\u56e0\u7f16\u8f91CAR-T\u7ec6\u80de\u7f16\u8f91\u7684CTX110\u548cCTX130\u5747\u5b9e\u73b0\u4e86\u6982\u5ff5\u9a8c\u8bc1\u3002CTX110\u6b63\u5904\u4e8e\u6cbb\u7597CD19+B\u7ec6\u80de\u6076\u6027\u80bf\u7624\u7684\u4e8c\u671f\u8bd5\u9a8c\uff0cCTX130\u6cbb\u7597\u5b9e\u4f53\u7624\u548c\u8840\u6db2\u75c5\uff0c\u4ee5CD70\u86cb\u767d\u8d28\u4e3a\u9776\u70b9\u7684\u4e00\u671fCOBALT-LYM\u8bd5\u9a8c\u7ed3\u679c\u79ef\u6781\uff0c\u56e0\u6b64\u8fd8\u83b7\u5f97\u4e86FDA\u7684\u518d\u751f\u533b\u5b66\u5148\u8fdb\u7597\u6cd5\u8ba4\u5b9a\u3002\u6b64\u5916\uff0c\u8be5\u516c\u53f8\u8fd8\u8054\u624bViaCyte\u5f00\u53d1\u6cbb\u7597\u4e00\u578b\u7cd6\u5c3f\u75c5\u7684VCTX-210\uff0c\u5e76\u4e14\u521a\u521a\u5b8c\u6210\u4e86\u4e00\u671f\u8bd5\u9a8c\u7684\u7ed9\u836f\u3002<\/p>\n
3. \u6ca1\u6709\u62a4\u57ce\u6cb3\u4f46\u5145\u6ee1\u4e86\u53ef\u80fd\u6027<\/h2>\n
CRISPR Therapeutics\u5e76\u4e0d\u662f\u552f\u4e00\u7684CRISPR\u57fa\u56e0\u7f16\u8f91\u516c\u53f8\uff0c\u56e0\u6b64\u5e76\u6ca1\u6709\u7ed3\u6784\u4e0a\u7684\u62a4\u57ce\u6cb3\u3002\u4e0d\u8fc7\uff0c\u5b83\u7684CRISPR-Cas9\u7f16\u8f91\u6280\u672f\u5bf9\u4e8e\u5355\u7ec6\u80de\u7a81\u53d8\u7684\u57fa\u56e0\u75be\u75c5\u5f88\u6709\u6548\uff0c\u800c\u8fd9\u7c7b\u75be\u75c5\u81f3\u5c11\u67091\u4e07\u79cd\uff0c\u6bd4\u5982\u8bf4\u56ca\u6027\u7ea4\u7ef4\u5316\u3001\u8840\u53cb\u75c5\u3001\u808c\u8425\u517b\u4e0d\u826f\u75c7\u4ee5\u53ca\u4ea8\u5ef7\u987f\u6c0f\u821e\u8e48\u75c5\u7b49\u3002\u622a\u81f312\u670831\u65e5\uff0c\u8be5\u516c\u53f8\u62a5\u544a\u73b0\u91d1\u53ca\u73b0\u91d1\u7b49\u4ef7\u7269$18.7\u4ebf\uff0c2022\u5e74\u6ca1\u6709\u6536\u5165\uff0c\u4e8f\u635f$6.502\u4ebf\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"
CRISPR Therapeutics\u7684\u80a1\u7968\u73b0\u5728\u8fd8\u4fbf\u5b9c\uff0c\u4f46\u4e0d\u4f1a\u6c38\u8fdc\u4fbf\u5b9c\u4e0b\u53bb \u8fc7\u53bb12\u4e2a\u6708\uff0c\u7f8e\u80a1\u5f88\u591a\u57fa\u56e0\u7f16\u8f91\u751f\u7269 […]<\/p>\n","protected":false},"author":27,"featured_media":450659,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1521,430],"tags":[455,747,925,459],"class_list":["post-454191","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1521","category-trends-strategies-zh-hans","tag-455","tag-747","tag-925","tag-459","sectors-life-science-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/454191","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=454191"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/454191\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/450659"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=454191"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=454191"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=454191"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}