{"id":456921,"date":"2023-04-05T01:14:07","date_gmt":"2023-04-05T08:14:07","guid":{"rendered":"https:\/\/nai500.com\/?p=456921"},"modified":"2023-04-05T01:22:56","modified_gmt":"2023-04-05T08:22:56","slug":"%e5%8d%8e%e5%b0%94%e8%a1%97%e8%bf%99%e4%ba%9b%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80%e8%82%a1%e5%8f%af%e8%83%bd%e4%bc%9a%e9%a3%99%e5%8d%87%e8%b6%85%e8%bf%87-100","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2023\/04\/%e5%8d%8e%e5%b0%94%e8%a1%97%e8%bf%99%e4%ba%9b%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80%e8%82%a1%e5%8f%af%e8%83%bd%e4%bc%9a%e9%a3%99%e5%8d%87%e8%b6%85%e8%bf%87-100\/","title":{"rendered":"\u534e\u5c14\u8857\uff1a\u8fd9\u4e9b\u751f\u7269\u79d1\u6280\u80a1\u53ef\u80fd\u4f1a\u98d9\u5347\u8d85\u8fc7100%"},"content":{"rendered":"<p>\u4e00\u4e9b\u534e\u5c14\u8857\u5206\u6790\u5e08\u79f0\uff0cArrowhead Pharmaceuticals\u548cSeres 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(ARWR)<\/a>\u901a\u8fc7\u5c16\u7aef\u7684RNA\u5e72\u6270\u5e73\u53f0\uff0c\u6210\u4e3a\u4e86\u65b0\u5174\u57fa\u56e0\u6c89\u9ed8\u9886\u57df\u7684\u9886\u5bfc\u8005\u3002\u8be5\u516c\u53f8\u62e5\u6709\u5404\u79cd\u5404\u6837\u7684\u8bb8\u53ef\u4ea4\u6613\u5e76\u4e14\u4e0e\u5927\u836f\u5382\u5408\u4f5c\u3002\u7136\u800c\uff0cArrowhead\u7684\u4ef7\u503c\u4e3b\u5f20\u4ecd\u672a\u80fd\u5f97\u5230\u6295\u8d44\u8005\u7684\u8ba4\u53ef\u3002\u7531\u4e8e\u5bf9\u03b1-1\u6297\u80f0\u86cb\u767d\u9176\uff08AATD\uff09\u809d\u75c5\u7684\u6570\u636e\u89e3\u8bfb\u6a21\u7cca\u4e0d\u6e05\uff0c\u4ee5\u53ca\u5f3a\u751f\u516c\u53f8\u7ed3\u675f\u4e86\u53cc\u65b9\u4ef7\u503c37\u4ebf\u7f8e\u5143\u7684\u5408\u4f5c\uff0cArrowhead\u7684\u80a1\u4ef7\u5728\u8fc7\u53bb\u4e00\u5e74\u4e2d\u5df2\u7ecf\u4e0b\u8dcc\u4e86\u8fd150%\u3002<\/p>\n<p>\u4e0d\u8fc7\uff0c\u770b\u6da8\u8be5\u80a1\u7684\u5206\u6790\u5e08\u4eec\u8ba4\u4e3a\u80a1\u4ef7\u4e0b\u8dcc\u8fc7\u5934\u4e86\u3002\u5206\u6790\u5e08\u5bf9\u8be5\u516c\u53f8\u80a1\u7968\u7684\u4e00\u81f4\u76ee\u6807\u4ef7\u610f\u5473\u7740\u6709\u60ca\u4eba\u7684130%\u7684\u4e0a\u5347\u6f5c\u529b\u3002<\/p>\n<p>\u57282023\u5e74\u671f\u95f4\uff0c\u9884\u8ba1Arrowhead\u5c06\u542f\u52a8\u4e00\u4e9b\u540e\u671f\u8bd5\u9a8c\uff0c\u5e76\u516c\u5e03\u5927\u91cf\u6d89\u53ca\u5404\u79cd\u9002\u5e94\u75c7\u7684\u4e00\u7ebf\u4e34\u5e8a\u6570\u636e\u3002\u56e0\u6b64\uff0c\u8be5\u516c\u53f8\u6709\u771f\u6b63\u673a\u4f1a\u5728\u4eca\u5e74\u4e3a\u80a1\u4e1c\u521b\u9020\u5de8\u5927\u4ef7\u503c\u3002<\/p>\n<h2>Seres 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