{"id":459687,"date":"2023-05-03T23:13:02","date_gmt":"2023-05-04T06:13:02","guid":{"rendered":"https:\/\/nai500.com\/?p=459687"},"modified":"2023-05-04T02:40:25","modified_gmt":"2023-05-04T09:40:25","slug":"%e4%bb%8a%e5%b9%b4%e8%82%a1%e4%bb%b7%e4%b8%8a%e6%b6%a8%e8%af%a5%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80%e8%82%a1%e5%a4%87%e5%8f%97%e5%85%b3%e6%b3%a8","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2023\/05\/%e4%bb%8a%e5%b9%b4%e8%82%a1%e4%bb%b7%e4%b8%8a%e6%b6%a8%e8%af%a5%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80%e8%82%a1%e5%a4%87%e5%8f%97%e5%85%b3%e6%b3%a8\/","title":{"rendered":"\u4eca\u5e74\u80a1\u4ef7\u4e0a\u6da8\u8d85\u8fc7151%\uff0c\u8be5\u751f\u7269\u79d1\u6280\u80a1\u5907\u53d7\u5173\u6ce8"},"content":{"rendered":"<p>\u7f8e\u56fd\u5f53\u5730\u65f6\u95f4\u5468\u4e09\uff085\u67083\u65e5\uff09\u4e0a\u5348\uff0c<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=MGN\">ImmunoGen\uff08MGN\uff09<\/a>\u7684\u80a1\u4ef7\u4e0a\u6da8\u4e86139%\uff0c\u6b64\u524d\u8be5\u516c\u53f8\u5ba3\u5e03\u4e86\u6b63\u5728\u7814\u53d1\u7684\u4e00\u79cd\u5375\u5de2\u764c\u836f\u7269\u7684\u79ef\u6781\u8bd5\u9a8c\u6570\u636e\u3002\u8be5\u751f\u7269\u79d1\u6280\u80a1\u4eca\u5e74\u4e0a\u6da8\u8d85\u8fc7151%\u3002<\/p>\n<p>ImmunoGen\u4e13\u6ce8\u4e8e\u6297\u764c\u6297\u4f53\u836f\u7269\u5076\u8054\u7269\u3002\u5468\u4e09\uff0c\u8be5\u516c\u53f8\u5ba3\u5e03\u4e3b\u8981\u5019\u9009\u7597\u6cd5Elahere\u57283\u671f\u9a8c\u8bc1\u8bd5\u9a8c\u4e2d\u8868\u73b0\u826f\u597d\uff0cElahere\u7528\u4e8e\u6cbb\u7597\u63a5\u53d7\u8fc7\u5316\u7597\u7684\u53f6\u9178\u53d7\u4f53\u03b1(FR\u03b1)\u9633\u6027\u7684\u94c2\u8010\u836f\u5375\u5de2\u60a3\u8005\u3002ImmunoGen\u8868\u793a\uff0c\u73b0\u5728\u8ba1\u5212\u5728\u7f8e\u56fd\u63d0\u4ea4\u4e00\u4efd\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7(BLA)\uff0c\u5e76\u5728\u6b27\u6d32\u63d0\u4ea4\u4e00\u4efd\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7(MAA)\uff0c\u4ee5\u83b7\u5f97\u8be5\u836f\u7269\u7684\u5168\u9762\u6279\u51c6\uff0c\u8be5\u836f\u7269\u4e8e\u53bb\u5e7411\u6708\u83b7\u5f97\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u5375\u5de2\u764c\u7684\u52a0\u901f\u6279\u51c6\u3002\u8be5\u8bd5\u9a8c\u7684\u4e00\u4e2a\u5173\u952e\u6570\u636e\u70b9\u662f\uff0cElahere\u7684\u5ba2\u89c2\u7f13\u89e3\u7387(ORR)\u4e3a42.3%\uff0c\u670912\u4f8b\u5b8c\u5168\u7f13\u89e3\uff0c\u800c\u63a5\u53d7\u94c2\u7c7b\u5316\u7597\u7684\u7814\u7a76\u53c2\u4e0e\u8005\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\u4e3a15.9%\uff0c\u6ca1\u6709\u5b8c\u5168\u7f13\u89e3\u3002<\/p>\n<p>\u5728\u622a\u81f33\u670831\u65e5\u7684\u7b2c\u4e00\u8d22\u5b63\uff0c\u8be5\u516c\u53f8\u6536\u5165\u4e3a4990\u4e07\u7f8e\u5143\u3002Elahere\u7684\u9500\u552e\u989d\u53ef\u80fd\u6210\u4e3a\u5e2e\u52a9\u8be5\u516c\u53f8\u5f00\u53d1\u5176\u4f59\u4ea7\u54c1\u7ebf\u7684\u5f15\u64ce\uff0c\u5176\u4e2d\u5305\u62ec\u5176\u4ed6\u4e09\u79cd\u80bf\u7624\u7597\u6cd5\uff1apivekimab sunirine\uff1bIMGC936\u548cIMGN151\u3002\u4e0a\u5468\uff0c\u5728\u8be5\u516c\u53f8\u5ba3\u5e03\u7b2c\u4e00\u8d22\u5b63\u6536\u76ca\u548c2023\u5e74\u4e1a\u7ee9\u6307\u5f15\u540e\uff0c\u8be5\u516c\u53f8\u8868\u793a\u9884\u8ba1\u4eca\u5e74\u7684\u6536\u5165\u5c06\u57284500\u4e07\u81f35000\u4e07\u7f8e\u5143\u4e4b\u95f4\uff0c\u5373\u4f7f\u6ca1\u6709Elahere\u7684\u6536\u5165\uff0c\u8be5\u80a1\u4e5f\u5df2\u7ecf\u4e0a\u6da8\u3002\u8be5\u836f\u7269\u5177\u6709\u5de8\u5927\u7684\u6f5c\u5728\u76ee\u6807\u5e02\u573a\uff0c\u7f8e\u56fd\u764c\u75c7\u534f\u4f1a\u4f30\u8ba1\u4eca\u5e74\u7f8e\u56fd\u5c06\u670919,710\u540d\u5973\u6027\u88ab\u8bca\u65ad\u51fa\u60a3\u6709\u5375\u5de2\u764c\uff0c2023\u5e74\u5c06\u670913,270\u540d\u7f8e\u56fd\u5973\u6027\u56e0\u5375\u5de2\u764c\u6b7b\u4ea1\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7f8e\u56fd\u5f53\u5730\u65f6\u95f4\u5468\u4e09\uff085\u67083\u65e5\uff09\u4e0a\u5348\uff0cImmunoGen\uff08MGN\uff09\u7684\u80a1\u4ef7\u4e0a\u6da8\u4e86139%\uff0c\u6b64\u524d\u8be5\u516c\u53f8\u5ba3\u5e03\u4e86\u6b63\u5728\u7814\u53d1\u7684 [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":459696,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[427],"tags":[455,747,459],"class_list":["post-459687","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hans","tag-455","tag-747","tag-459","sectors-life-science-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans","exchange-nyse-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/459687","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=459687"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/459687\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/459696"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=459687"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=459687"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=459687"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}