{"id":476732,"date":"2023-11-02T18:26:38","date_gmt":"2023-11-03T01:26:38","guid":{"rendered":"https:\/\/nai500.com\/?p=476732"},"modified":"2023-11-02T18:27:48","modified_gmt":"2023-11-03T01:27:48","slug":"%e5%88%9b%e6%96%b0%e5%88%9b%e9%80%a0%e8%b4%a2%e5%af%8c-%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1%e7%a5%a8-%e5%8c%bb%e7%96%97%e5%88%9b%e6%96%b0%e7%9a%84%e6%9c%80%e5%89%8d%e6%b2%bf","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2023\/11\/%e5%88%9b%e6%96%b0%e5%88%9b%e9%80%a0%e8%b4%a2%e5%af%8c-%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1%e7%a5%a8-%e5%8c%bb%e7%96%97%e5%88%9b%e6%96%b0%e7%9a%84%e6%9c%80%e5%89%8d%e6%b2%bf\/","title":{"rendered":"\u521b\u65b0\u521b\u9020\u8d22\u5bcc\uff0c\u800c\u8fd9\u53ea\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u6b63\u597d\u7ad9\u5728\u4e86\u533b\u7597\u521b\u65b0\u7684\u6700\u524d\u6cbf"},"content":{"rendered":"

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\u6bd4\u5982\u8bf4\uff0c\u5982\u679c1981\u5e74\u6295\u8d44\u8f89\u745e\u5236\u836fPfizer\uff08NYSE:PFE\uff091\u4e07\u7f8e\u5143\uff0c\u62ff\u5230\u73b0\u5728\u8fd9\u7b14\u521d\u59cb\u6295\u8d44\u5df2\u7ecf\u8d85\u8fc7100\u4e07\u7f8e\u5143\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u540c\u6837\u7684\u4e00\u7b14\u94b1\u6295\u8d44\u8868\u73b0\u6700\u597d\u7684\u5171\u540c\u57fa\u91d1\uff0c\u6700\u7ec8\u4e5f\u7a81\u7834\u4e0d\u4e8690\u4e07\u7f8e\u5143\u3002<\/p>\n

\u5236\u836f\u80a1\u7968\u521b\u9020\u8d22\u5bcc\u5947\u8ff9\u7684\u79d8\u8bc0\u662f\u4ec0\u4e48\uff1f\u8fd9\u4e9b\u9ad8\u6210\u957f\u80a1\u7968\u8d85\u51e1\u589e\u957f\u7684\u9a71\u52a8\u529b\u53c8\u662f\u4ec0\u4e48\uff1f\u8fd9\u4e2a\u95ee\u9898\u7684\u7b54\u6848\u6709\u5f88\u591a\uff0c\u6bd4\u5982\u8bf4\u5168\u7403\u4eba\u53e3\u7684\u8001\u9f84\u5316\u5e26\u52a8\u533b\u7597\u9700\u6c42\u6301\u7eed\u589e\u957f\uff0c\u6216\u8005\u662f\u5168\u7403\u533b\u7597\u8bbe\u5907\u7684\u65e5\u76ca\u666e\u53ca\uff0c\u4f46\u6700\u91cd\u8981\u7684\u56e0\u7d20\u662f\u521b\u65b0\u3002<\/p>\n

\u5728\u65b0\u6280\u672f\u7684\u52a9\u529b\u4e4b\u4e0b\uff0c\u539f\u672c\u4ee5\u4e3a\u65e0\u6cd5\u533b\u6cbb\u7684\u75be\u75c5\u88ab\u4e0d\u65ad\u653b\u7834\uff0c\u800c\u8fd9\u4e9b\u5b9e\u73b0\u521b\u65b0\u7684\u9f99\u5934\u516c\u53f8\uff0c\u6bd4\u5982\u8bf4\u5b89\u8fdbAmgen\uff08NASDAQ:AMGN\uff09\u548c\u518d\u751f\u5143\u5236\u836fRegeneron Pharmaceuticals\uff08NASDAQ:REGN\uff09\u5728\u8fd9\u4e00\u8fc7\u7a0b\u4e2d\u521b\u9020\u51fa\u4e86\u5de8\u5927\u7684\u8d22\u5bcc\u3002<\/p>\n

CRISPR\/Cas9\u57fa\u56e0\u7f16\u8f91\u6280\u672f\uff0c\u533b\u7597\u521b\u65b0\u7684\u65b0\u524d\u6cbf<\/h2>\n

\u5355\u514b\u9686\u6297\u4f53\u4ee5\u53ca\u7c7b\u4f3c\u6280\u672f\u51fa\u73b0\u4e4b\u540e\uff0c\u533b\u7597\u884c\u4e1a\u5c06\u8fce\u6765\u53e6\u4e00\u9879\u6709\u671b\u6210\u4e3a\u8d22\u5bcc\u52a0\u901f\u5668\u7684\u521b\u65b0\u6280\u672f\uff0c\u4e5f\u5c31\u662fCRISPR\/Cas9\u57fa\u56e0\u7f16\u8f91\u3002<\/p>\n

\u867d\u7136\u73b0\u5728\u5e02\u573a\u4e0a\u7684\u57fa\u56e0\u7f16\u8f91\u4e0a\u5e02\u516c\u53f8\u4e5f\u4e0d\u5c11\uff0c\u4f46\u4ece\u8d44\u672c\u589e\u503c\u6f5c\u529b\u51fa\u53d1\uff0cIntellia Therapeutics Inc\uff08NASDAQ:NTLA\uff09<\/a>\u7edd\u5bf9\u662f\u5176\u4e2d\u7684\u4f7c\u4f7c\u8005\u3002\u8be5\u57fa\u56e0\u7597\u6cd5\u516c\u53f8\u8054\u624b\u518d\u751f\u5143\u5236\u836fRegeneron Pharmaceuticals\uff08NASDAQ:REGN\uff09\u5f00\u5c55\u7684NTLA-2001\u6cbb\u7597\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\uff08ATTR\uff09\u6dc0\u7c89\u6837\u53d8\u6027\u7684\u7814\u53d1\u9879\u76ee\u5e74\u5e95\u524d\u5c06\u8fdb\u5165\u5173\u952e\u7684\u4e09\u671f\u7814\u7a76\u3002<\/p>\n

Intellia\u771f\u7684\u8fd9\u4e48\u725b\u5417\uff1f\u8fc7\u53bb24\u4e2a\u6708\uff0c\u6295\u8d44\u8005\u66f4\u52a0\u5173\u6ce8\u516c\u53f8\u7684\u57fa\u672c\u9762\uff0c\u751f\u7269\u79d1\u6280\u80a1\u7968\u7684\u4f30\u503c\u88ab\u6324\u538b\uff0c\u8fd9\u53ea\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u7684\u4ef7\u683c\u8fc7\u53bb12\u4e2a\u6708\u4e5f\u66b4\u8dcc52%\u3002\u4f46\u662f\uff0c\u8fd9\u53ea\u80a1\u7968\u7684\u771f\u6b63\u5438\u5f15\u529b\u5728\u4e8e\u5b83\u7684\u6df1\u5ea6\u4ef7\u503c\u4e3b\u5f20\u3002\u8be5\u516c\u53f8\u5728\u7814\u836f\u7269\u6570\u91cf\u591a\uff0c\u672a\u676510\u5e74\u5185\u6709\u671b\u62ff\u51fa3\u4e2a\u751a\u81f3\u662f4\u4e2a\u91cd\u78c5\u7597\u6cd5\u3002<\/p>\n

\u5f53\u7136\u4e86\uff0cCRISPR\/Cas9\u5728\u4e34\u5e8a\u4e0a\u8fd8\u6709\u5f88\u591a\u4e1c\u897f\u9700\u8981\u8bc1\u660e\uff0c\u8fd9\u4e00\u770b\u6da8\u8bbe\u60f3\u4e5f\u4e0d\u662f\u94c1\u677f\u9489\u9489\u7684\u7ed3\u8bba\u3002\u4f46\u662f\uff0c\u6295\u8d44\u8005\u5c06\u89c1\u8bc1\u4e00\u4e2a\u65b0\u7684\u91cd\u5927\u533b\u7597\u521b\u65b0\u7684\u8bde\u751f\uff0c\u8fd9\u79cd\u53ef\u80fd\u6027\u662f\u771f\u771f\u5b9e\u5b9e\u5b58\u5728\u7684\uff0c\u4f46\u76ee\u524d\u7684\u5e02\u573a\u5e76\u672a\u5bf9\u6b64\u4e88\u4ee5\u53cd\u5e94\u3002<\/p>\n

Intellia\u80a1\u7968\u76ee\u524d\u7684\u5e02\u503c\u8fd8\u4e0d\u5230\u5e93\u5b58\u73b0\u91d1\u76843\u500d\uff0c\u806a\u660e\u7684\u6295\u8d44\u8005\u53ef\u4ee5\u9022\u4f4e\u4e70\u5165\u8fd9\u53ea\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u3002\u4e0d\u7ba1\u600e\u4e48\u8bf4\uff0c\u8fc7\u53bb80\u5e74\u6700\u725b\u7684\u725b\u80a1\u4e5f\u4f1a\u56e0\u4e3a\u5e02\u573a\u60c5\u7eea\u7684\u53d8\u5316\u51fa\u73b0\u80a1\u4ef7\u7684\u6da8\u8dcc\uff0c\u4f46\u5b83\u4eec\u6700\u7ec8\u90fd\u4e3a\u65e9\u671f\u80a1\u4e1c\u521b\u9020\u4e86\u6539\u53d8\u4eba\u751f\u7684\u6536\u76ca\u3002<\/p>\n

\u5c0f\u7ed3<\/h2>\n

Intellia\u867d\u7136\u6709\u98ce\u9669\uff0c\u4f46\u5177\u5907\u8ba9\u6295\u8d44\u6210\u4e3a\u767e\u4e07\u5bcc\u7fc1\u7684\u6f5c\u529b\uff0c\u800c\u4e14\u8fd9\u6b21\u65e0\u9700\u82b1\u8d3940\u591a\u5e74\u7684\u65f6\u95f4\u3002\u4ec5\u4ec510\u5e74\u65f6\u95f4\uff0cCRISPR\/Cas9\u5c31\u5df2\u7ecf\u4ece\u4e00\u4e2a\u6982\u5ff5\u6210\u4e3a\u5373\u5c06\u4e0a\u5e02\u7684\u4ea7\u54c1\u3002\u867d\u8bf4\u751f\u7269\u79d1\u6280\u80a1\u7684\u718a\u5e02\u8fd8\u5728\u6301\u7eed\uff0c\u4f46\u968f\u7740NTLA-2001\u4e09\u671f\u8bd5\u9a8c\u7684\u542f\u52a8\uff0c\u8fd9\u53ea\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u79d1\u6280\u80a1\u7968\u503c\u5f97\u4e00\u640f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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