{"id":478261,"date":"2023-11-17T00:09:19","date_gmt":"2023-11-17T08:09:19","guid":{"rendered":"https:\/\/nai500.com\/?p=478261"},"modified":"2023-11-17T00:09:19","modified_gmt":"2023-11-17T08:09:19","slug":"%e5%af%bb%e6%89%be%e8%a6%81%e8%b4%ad%e4%b9%b0%e7%9a%84%e8%82%a1%e7%a5%a8%e4%bb%a5%e4%b8%8b%e6%98%af%e5%bc%ba%e7%94%9f%e5%85%ac%e5%8f%b8%e6%9c%80%e7%9c%8b%e9%87%8d%e7%9a%84%e5%85%ac%e5%8f%b8","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2023\/11\/%e5%af%bb%e6%89%be%e8%a6%81%e8%b4%ad%e4%b9%b0%e7%9a%84%e8%82%a1%e7%a5%a8%e4%bb%a5%e4%b8%8b%e6%98%af%e5%bc%ba%e7%94%9f%e5%85%ac%e5%8f%b8%e6%9c%80%e7%9c%8b%e9%87%8d%e7%9a%84%e5%85%ac%e5%8f%b8\/","title":{"rendered":"\u5bfb\u627e\u8981\u8d2d\u4e70\u7684\u80a1\u7968\uff1f\u4ee5\u4e0b\u662f\u5f3a\u751f\u516c\u53f8\u6700\u770b\u91cd\u7684\u516c\u53f8"},"content":{"rendered":"

\u5982\u679c\u60a8\u6b63\u5728\u5bfb\u627e\u4e00\u5bb6\u65b0\u9910\u5385\u5c1d\u8bd5\uff0c\u8457\u540d\u53a8\u5e08\u7684\u63a8\u8350\u53ef\u80fd\u4f1a\u5f88\u91cd\u8981\u3002\u5982\u679c\u60a8\u60f3\u627e\u4e00\u4f4d\u5d2d\u9732\u5934\u89d2\u7684\u6b4c\u624b\u7684\u6b4c\u6765\u542c\uff0c\u60a8\u53ef\u80fd\u4f1a\u770b\u770b\u4e00\u4f4d\u4f20\u5947\u97f3\u4e50\u5bb6\u63a8\u8350\u7684\u6b4c\u624b\u3002<\/p>\n

\u4f46\u662f\uff0c\u5982\u679c\u60a8\u6b63\u5728\u5bfb\u627e\u8981\u8d2d\u4e70\u7684\u80a1\u7968\u600e\u4e48\u529e\uff1f\u4e5f\u8bb8\u4f60\u53ef\u4ee5\u627e\u51fa\u4e00\u5bb6\u957f\u671f\u6210\u529f\u7684\u77e5\u540d\u516c\u53f8\u771f\u6b63\u559c\u6b22\u54ea\u4e9b\u80a1\u7968\u2014\u2014\u6bd4\u5982\u5f3a\u751f\u516c\u53f8\uff08JNJ\uff09<\/a>\u3002\u597d\u6d88\u606f\u662f\u6211\u4eec\u53ea\u9700\u67e5\u770b\u8fd9\u5bb6\u533b\u7597\u4fdd\u5065\u5de8\u5934\u768413F\u76d1\u7ba1\u6587\u4ef6\u5373\u53ef\u3002\u4ee5\u4e0b\u662f\u5f3a\u751f\u62bc\u6ce8\u6700\u591a\u7684\u4e09\u53ea\u80a1\u7968\u3002<\/p>\n

Legend Biotech<\/h2>\n

\u622a\u81f32023\u5e749\u670830\u65e5\uff0c\u5f3a\u751f\u6700\u5927\u7684\u6295\u8d44\u662fLegend Biotech\uff08LEGN\uff09<\/a>\u3002\u5f3a\u751f\u516c\u53f8\u5728\u8fd9\u5bb6\u5c0f\u578b\u751f\u7269\u5236\u836f\u516c\u53f8\u7684\u80a1\u4efd\u4ef7\u503c\u8d85\u8fc75470\u4e07\u7f8e\u5143\u3002<\/p>\n

2017\u5e74\uff0c\u5f3a\u751f\u516c\u53f8\u4e0eLegend Biotech\u5408\u4f5c\u5f00\u53d1\u4e86\u4e00\u79cd\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\uff08CAR-T\uff09\u5019\u9009\u836f\u7269\uff0c\u540d\u4e3aLCAR-B38M\u3002\u5f3a\u751f\u516c\u53f8\u83b7\u5f97\u4e86\u4e0eLegend\u8054\u5408\u5f00\u53d1\u548c\u9500\u552eCAR-T\u7597\u6cd5\u7684\u5168\u7403\u8bb8\u53ef\uff0c\u9884\u4ed8\u6b3e\u4e3a3.5\u4ebf\u7f8e\u5143\uff0c\u5916\u52a0\u6216\u6709\u7684\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002<\/p>\n

\u6b64\u6b21\u5408\u4f5c\u4f3c\u4e4e\u6709\u671b\u53d6\u5f97\u826f\u597d\u56de\u62a5\u3002LCAR-B38M\uff08\u73b0\u79f0\u4e3aCarvykti\uff09\u4e8e2022\u5e74\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40(FDA)\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u3002<\/p>\n

\u5f3a\u751f\u5e76\u4e0d\u662fLegend Biotech\u5438\u5f15\u7684\u552f\u4e00\u4e00\u5bb6\u5927\u578b\u5236\u836f\u516c\u53f8\u3002\u5c31\u5728\u51e0\u5929\u524d\uff0cLegend Biotech\u5ba3\u5e03\u8fbe\u6210\u534f\u8bae\uff0c\u4ee51\u4ebf\u7f8e\u5143\u7684\u9884\u4ed8\u6b3e\u4ee5\u53ca\u9ad8\u8fbe10.1\u4ebf\u7f8e\u5143\u7684\u6f5c\u5728\u91cc\u7a0b\u7891\u4ed8\u6b3e\uff0c\u5411\u8bfa\u534e\u6388\u6743\u5176\u4ed6\u4e00\u4e9bCAR-T\u9879\u76ee\uff0c\u5305\u62ecLB2102\u3002<\/p>\n

CVRx<\/h2>\n

\u5728\u5f3a\u751f\u516c\u53f8\u7684\u6295\u8d44\u7ec4\u5408\u4e2d\uff0c\u5bf9CVRx (CVRX)<\/a>\u7684\u6301\u80a1\u4ef7\u503c\u7d27\u968fLegend Biotech\u4e4b\u540e\u3002\u622a\u81f39\u6708\u5e95\uff0c\u5f3a\u751f\u5728CVRx\u7684\u6301\u80a1\u4ef7\u503c\u7565\u9ad8\u4e8e5300\u4e07\u7f8e\u5143\u3002<\/p>\n

\u4e0eLegend Biotech\u4e0d\u540c\uff0cCVRx\u4e0d\u662f\u5236\u836f\u5546\u3002CVRx\u5f00\u53d1\u548c\u9500\u552e\u5fc3\u529b\u8870\u7aed\u8bbe\u5907\u3002\u5176Barostim\u7cfb\u7edf\u662f\u7b2c\u4e00\u4e2a\u83b7\u5f97FDA\u6279\u51c6\u7684\u533b\u7597\u8bbe\u5907\uff0c\u5229\u7528\u795e\u7ecf\u8c03\u8282\uff08\u795e\u7ecf\u5143\u7684\u7535\u523a\u6fc0\uff09\u6765\u5e2e\u52a9\u5fc3\u529b\u8870\u7aed\u60a3\u8005\u3002<\/p>\n

\u5f3a\u751f\u516c\u53f8\u4e0eCVRx\u7684\u5173\u7cfb\u53ef\u4ee5\u8ffd\u6eaf\u52302008\u5e74\uff0c\u5f53\u65f6\u5f3a\u751f\u516c\u53f8\u9996\u6b21\u6295\u8d44\u4e86\u8fd9\u5bb6\u533b\u7597\u8bbe\u5907\u5236\u9020\u5546\u30022016\u5e74\uff0c\u5f3a\u751f\u98ce\u9669\u6295\u8d44\u90e8\u95e8\u9886\u6295\u4e86CVRx\u7684G\u8f6e\u878d\u8d44\u3002<\/p>\n

CVRx\u4e8e2021\u5e747\u6708\u8fdb\u884c\u4e86\u9996\u6b21\u516c\u5f00\u52df\u80a1(IPO)\u3002\u81ea2022\u5e74\u4e2d\u671f\u4ee5\u6765\uff0cCVRx\u7684\u80a1\u4ef7\u5df2\u4e0a\u6da8\u4e24\u500d\u3002<\/p>\n

Protagonist Therapeutics<\/h2>\n

\u5f3a\u751f\u516c\u53f8\u7684\u7b2c\u4e09\u5927\u6301\u80a1\u662fProtagonist Therapeutics (PTGX)<\/a>\u3002\u622a\u81f32023\u5e74\u7b2c\u4e09\u8d22\u5b63\u672b\uff0c\u8fd9\u5bb6\u5927\u578b\u533b\u7597\u4fdd\u5065\u516c\u53f8\u62e5\u6709\u8fd1245\u4e07\u80a1Protagonist\u80a1\u7968\uff0c\u4ef7\u503c\u8d85\u8fc74080\u4e07\u7f8e\u5143\u3002<\/p>\n

\u65e9\u57282013\u5e74\uff0cProtagonist\u7684B\u8f6e\u878d\u8d44\u9996\u6b21\u5f15\u8d77\u4e86\u5f3a\u751f\u516c\u53f8\u7684\u5174\u8da3\u3002\u5f3a\u751f\u8fd8\u53c2\u4e0e\u4e86Protagonist\u7684C\u8f6e\u878d\u8d44\u3002<\/p>\n

2017\u5e74\uff0c\u53cc\u65b9\u5ba3\u5e03\u5c31Protagonist\u7684\u767d\u7ec6\u80de\u4ecb\u7d2023\u53d7\u4f53\u62ee\u6297\u5242\u5019\u9009\u836f\u7269PN-235\u8fbe\u6210\u8bb8\u53ef\u548c\u5408\u4f5c\u534f\u8bae\u3002Protagonist Therapeutics\u8fd8\u6709\u53e6\u4e00\u4e2a\u62e5\u6709\u5b8c\u5168\u6743\u5229\u7684\u5019\u9009\u7ba1\u7ebf\u3002\u8be5\u516c\u53f8\u6b63\u5728\u4e00\u9879\u9488\u5bf9\u7f55\u89c1\u75c5\u6cbb\u7597\u7684\u540e\u671f\u4e34\u5e8a\u7814\u7a76\u4e2d\u8bc4\u4f30rusfertide (PTG-300)\uff0c\u76ee\u6807\u662f\u6cbb\u7597\u591a\u53d1\u6027\u7ea2\u7ec6\u80de\u589e\u591a\u75c7\u3002<\/p>\n

\u60a8\u5e94\u8be5\u8ffd\u968f\u5f3a\u751f\u7684\u811a\u6b65\u5417\uff1f<\/h2>\n

\u4efb\u4f55\u4eba\u90fd\u4e0d\u5e94\u8be5\u4ec5\u4ec5\u56e0\u4e3a\u5f3a\u751f\u516c\u53f8\u6301\u6709\u8fd9\u4e09\u53ea\u80a1\u7968\u4e2d\u7684\u4efb\u4f55\u4e00\u53ea\u800c\u8d2d\u4e70\u5b83\u4eec\u3002\u6ce8\u610f\uff0c\u751f\u7269\u79d1\u6280\u548c\u533b\u7597\u5668\u68b0\u80a1\u7968\u5e76\u4e0d\u9002\u5408\u6bcf\u4e2a\u6295\u8d44\u8005\u3002\u53ea\u6709\u90a3\u4e9b\u4e0d\u6015\u627f\u62c5\u91cd\u5927\u98ce\u9669\u7684\u6fc0\u8fdb\u6295\u8d44\u8005\u624d\u5e94\u8be5\u8003\u8651\u8fd9\u4e9b\u80a1\u7968\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5982\u679c\u60a8\u6b63\u5728\u5bfb\u627e\u4e00\u5bb6\u65b0\u9910\u5385\u5c1d\u8bd5\uff0c\u8457\u540d\u53a8\u5e08\u7684\u63a8\u8350\u53ef\u80fd\u4f1a\u5f88\u91cd\u8981\u3002\u5982\u679c\u60a8\u60f3\u627e\u4e00\u4f4d\u5d2d\u9732\u5934\u89d2\u7684\u6b4c\u624b\u7684\u6b4c\u6765\u542c\uff0c\u60a8\u53ef\u80fd\u4f1a\u770b\u770b\u4e00 […]<\/p>\n","protected":false},"author":9,"featured_media":478262,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[427],"tags":[820,513,455,925],"class_list":["post-478261","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hans","tag-820","tag-513","tag-455","tag-925","sectors-life-science-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans","exchange-nyse-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/478261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=478261"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/478261\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/478262"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=478261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=478261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=478261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}