{"id":552599,"date":"2024-09-25T20:26:18","date_gmt":"2024-09-26T03:26:18","guid":{"rendered":"https:\/\/nai500.com\/?p=552599"},"modified":"2024-09-25T20:26:18","modified_gmt":"2024-09-26T03:26:18","slug":"%e4%bb%8a%e5%b9%b4%e9%a3%99%e5%8d%87-%e4%b8%a4%e5%8f%aa-%e7%be%8e%e8%82%a1%e6%8a%97%e7%99%8c%e8%8d%af%e8%82%a1%e7%a5%a8-%e7%bb%a7%e7%bb%ad%e6%b6%a8","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2024\/09\/%e4%bb%8a%e5%b9%b4%e9%a3%99%e5%8d%87-%e4%b8%a4%e5%8f%aa-%e7%be%8e%e8%82%a1%e6%8a%97%e7%99%8c%e8%8d%af%e8%82%a1%e7%a5%a8-%e7%bb%a7%e7%bb%ad%e6%b6%a8\/","title":{"rendered":"\u4eca\u5e74\u98d9\u5347\u8d85700%\u8fd8\u4e0d\u591f\uff0c\u8fd9\u4e24\u53ea\u7f8e\u80a1\u6297\u764c\u836f\u80a1\u7968\u8fd8\u80fd\u7ee7\u7eed\u6da8\uff01"},"content":{"rendered":"<p>\u4eca\u5e74\u7f8e\u80a1\u7684\u5927\u725b\u80a1\u5f53\u4e2d\uff0c\u6295\u8d44\u8005\u4eec\u53d1\u73b0\u4e86\u4e24\u5bb6\u764c\u75c7\u836f\u7269\u5f00\u53d1\u516c\u53f8\u3002\u4ece2023\u5e74\u5e95\u52302024\u5e749\u670823\u65e5\u6536\u76d8\u4e3a\u6b62\uff0c<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=SMMT\">Summit Therapeutics (SMMT) <\/a>\u548c Instil Bio (TIL)\u7684\u80a1\u4ef7\u5747\u4e0a\u6da8\u8d85\u8fc7700%\u3002\u8fd9\u4e9b\u80a1\u7968\u4e4b\u6240\u4ee5\u8868\u73b0\u4f18\u5f02\uff0c\u662f\u56e0\u4e3a\u5b83\u4eec\u5f00\u53d1\u7684\u65b0\u836f\u5019\u9009\u4ea7\u54c1\u53ef\u80fd\u6210\u4e3a\u8fd9\u4e2a\u65f6\u4ee3\u6700\u6210\u529f\u7684\u764c\u75c7\u6cbb\u7597\u624b\u6bb5\u4e4b\u4e00\uff0c\u5e74\u9500\u552e\u989d\u6709\u671b\u8fbe\u5230\u6570\u5341\u4ebf\u7f8e\u5143\u3002<\/p>\n<p>\u53bb\u5e74\uff0c\u4ec5\u9ed8\u514b\u516c\u53f8\u751f\u4ea7\u7684\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u836f\u7269Keytruda\u5c31\u5b9e\u73b0\u4e86250\u4ebf\u7f8e\u5143\u7684\u9500\u552e\u989d\u3002\u6700\u8fd1\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u8868\u660e\uff0cSummit Therapeutics\u548cInstil Bio\u5404\u81ea\u6b63\u5728\u7814\u53d1\u7684\u5019\u9009\u836f\u7269\u524d\u666f\u53ef\u671f\u3002\u5982\u679c\u8bd5\u9a8c\u53d6\u5f97\u6210\u529f\uff0c\u8fd9\u4e24\u53ea\u524d\u5546\u4e1a\u5316\u9636\u6bb5\u5236\u836f\u5546\u7684\u80a1\u4ef7\u5c06\u6da8\u7834\u5929\u9645\u3002<\/p>\n<h2>1. Summit Therapeutics<\/h2>\n<p>Summit Therapeutics\u7684\u80a1\u4ef7\u66fe\u4e00\u5ea6\u4e0a\u6da8\u8d85\u8fc71000%\uff0c\u7136\u540e\u56de\u843d\u3002\u52309\u670823\u65e5\u6536\u76d8\u65f6\uff0c\u8be5\u80a12024\u5e74\u7684\u6da8\u5e45\u4f9d\u7136\u9ad8\u8fbe739.5%\u3002Summit\u80a1\u4ef7\u4e4b\u6240\u4ee5\u98d9\u5347\uff0c\u662f\u56e0\u4e3aAkeso\u6388\u6743\u7684\u80ba\u764c\u6cbb\u7597\u836f\u7269ivonescimab\u5728\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u8868\u73b0\u4f18\u4e8eKeytruda\u3002<\/p>\n<p>\u5728\u4e2d\u56fd\uff0cSummit\u7684\u5408\u4f5c\u4f19\u4f34\u5eb7\u65b9\u751f\u7269\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u540d\u4e3aHARMONi-2\u7684\u5934\u5bf9\u5934\u4e09\u671f\u8bd5\u9a8c\uff0c\u9488\u5bf9\u65b0\u8bca\u65ad\u7684\u80ba\u764c\u60a3\u8005\u3002\u4e2d\u671f\u5206\u6790\u663e\u793a\uff0c\u76f8\u6bd4Keytruda\uff0civonescimab\u6cbb\u7597\u60a3\u8005\u7684\u75be\u75c5\u6076\u5316\u98ce\u9669\u964d\u4f4e\u4e8649%\u3002\u53bb\u5e7410\u6708\uff0cSummit\u5728\u5317\u7f8e\u542f\u52a8\u4e86HARMONi-3\u8bd5\u9a8c\uff0c\u62db\u52df\u4e86400\u540d\u4e00\u7ebf\u80ba\u764c\u60a3\u8005\u3002\u8fd9\u9879\u7814\u7a76\u5c06\u6bd4\u8f83\u5316\u7597+Keytruda\u4e0e\u5316\u7597+ivonescimab\u8054\u5408\u7597\u6cd5\u7684\u7597\u6548\u3002<\/p>\n<p>\u4e2d\u56fd\u76d1\u7ba1\u673a\u6784\u5df2\u4e8e\u4e94\u6708\u6279\u51c6\u4e86ivonescimab\u4e0e\u5316\u7597\u8054\u5408\u4f7f\u7528\uff0c\u7528\u4e8e\u4e8c\u7ebf\u80ba\u764c\u60a3\u8005\u7684\u6cbb\u7597\u3002\u867d\u7136Summit\u7684\u6388\u6743\u4e0d\u5305\u62ec\u5728\u4e2d\u56fd\u6216\u6fb3\u5927\u5229\u4e9a\u7684\u9500\u552e\uff0c\u4f46\u8fd9\u81f3\u5c11\u8868\u660e\u8be5\u836f\u7269\u5df2\u7ecf\u83b7\u5f97\u4e86\u4e00\u4e2a\u653f\u5e9c\u76d1\u7ba1\u673a\u6784\u7684\u8ba4\u53ef\u3002<\/p>\n<p>Summit\u4ee5\u80ba\u764c\u4f5c\u4e3a\u7a81\u7834\u53e3\uff0c\u56e0\u4e3a\u8fd9\u662f\u76ee\u524d\u6700\u81f4\u547d\u7684\u764c\u75c7\u4e4b\u4e00\uff0c\u4f46\u516c\u53f8\u5e76\u4e0d\u6b62\u6b65\u4e8e\u6b64\u3002Summit\u6700\u8fd1\u62a5\u544a\u79f0\uff0civonescimab\u5728\u7ed3\u80a0\u3001\u4e73\u817a\u3001\u5934\u9888\u7b49\u5b9e\u4f53\u80bf\u7624\u4e2d\u663e\u793a\u51fa\u8f83\u597d\u7684\u7f13\u89e3\u7387\u3002<\/p>\n<h2>2. Instil Bio<\/h2>\n<p>Instil Bio\u662f\u53e6\u4e00\u5bb6\u4ece\u4e2d\u56fd\u5408\u4f5c\u4f19\u4f34\u90a3\u91cc\u83b7\u5f97\u53cc\u7279\u5f02\u6027PD-1\/VEGF\u6297\u4f53\u6388\u6743\u7684\u7f8e\u56fd\u5236\u836f\u5546\u3002\u5b9c\u660e\u6602\u79d1\u6388\u6743\u7684\u836f\u7269\u4e3aIMM2510\uff0cInstil\u6682\u65f6\u547d\u540d\u4e3aSYN-2510\u3002\u867d\u7136\u6211\u4eec\u6ca1\u6709SYN-2510\u548cKeytruda\u7684\u5bf9\u6bd4\u6570\u636e\uff0c\u4f46\u4e0d\u59a8\u788dInstil Bio\u80a1\u4ef7\u7684\u66b4\u6da8\u3002\u622a\u81f39\u670824\u65e5\u65e9\u76d8\uff0c\u8fd9\u5bb6\u4e34\u5e8a\u9636\u6bb5\u5236\u836f\u5546\u7684\u80a1\u4ef7\u57282024\u5e74\u4e0a\u6da8\u4e86814%\u3002<\/p>\n<p>\u5728\u7814\u53d1\u8fdb\u5ea6\u4e0a\uff0cSYN-2510\u8981\u8fdc\u8fdc\u843d\u540e\u4e8eivonescimab\uff0c\u4f46Instil Bio\u548c\u5b9c\u660e\u6602\u79d1\u5df2\u5236\u5b9a\u4e86\u8ffd\u8d76\u8ba1\u5212\u3002\u8fd9\u5bb6\u4e2d\u56fd\u5408\u4f5c\u4f19\u4f34\u6700\u8fd1\u5ba3\u5e03\u4e86\u540e\u671f\u5f00\u53d1\u7b56\u7565\uff0c\u5176\u4e2d\u5305\u62ec\u9884\u8ba1\u4eca\u5e74\u665a\u4e9b\u65f6\u5019\u5728\u4e2d\u56fd\u542f\u52a8\u4e00\u7ebf\u80ba\u764c\u8bd5\u9a8c\u3002\u6b64\u5916\uff0cInstil\u9884\u8ba1\u4e5f\u5c06\u5728\u4eca\u5e74\u5728\u7f8e\u56fd\u542f\u52a8SYN-2510\u4f5c\u4e3a\u4e8c\u7ebf\u80ba\u764c\u6cbb\u7597\u7684\u4e8c\u671f\u8bd5\u9a8c\u3002\u4f5c\u7528\u673a\u5236\u4e0a\uff0cSYN-2510\u4f5c\u7528\u4e8e\u80bf\u7624\u7ec6\u80de\u4e0a\u7684PD-L1\uff0c\u800civonescimab\u5219\u9776\u5411\u514d\u75ab\u7ec6\u80de\u4e0a\u7684PD-1\u3002\u6b64\u5916\uff0cSYN-2510\u7ed3\u5408\u591a\u79cdVEGF\u914d\u4f53\uff0c\u4e0d\u4ec5\u9650\u4e8eivonescimab\u7684VEGF-A\u3002<\/p>\n<h2>Summit Therapeutics\u8fd8\u662fInstil Bio\uff1f<\/h2>\n<p>\u867d\u7136ivonescimab\u6709\u53ef\u80fd\u6210\u4e3a\u9886\u5148\u7684\u80ba\u764c\u6cbb\u7597\u836f\u7269\uff0c\u4f46Summit Therapeutics\u7684\u5e02\u503c\u4e5f\u5df2\u589e\u81f3\u7ea6159\u4ebf\u7f8e\u5143\u3002\u5bf9\u4e8e\u4e00\u5bb6\u5c1a\u65e0\u4ea7\u54c1\u53ef\u5356\u7684\u516c\u53f8\u6765\u8bf4\uff0c\u4f30\u503c\u98ce\u9669\u4e0d\u4f4e\uff0c\u4efb\u4f55\u8d1f\u9762\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u90fd\u53ef\u80fd\u5bf9\u8be5\u80a1\u9020\u6210\u6253\u51fb\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0cInstil Bio\u5e02\u503c\u53ea\u67094.51\u4ebf\u7f8e\u5143\u3002\u4e0d\u8fc7\uff0c\u7531\u4e8e\u6709\u5173\u8be5\u516c\u53f8\u53cc\u7279\u5f02\u6027\u6297\u4f53SYN-2510\u7684\u4fe1\u606f\u6709\u9650\uff0c\u8fd9\u5f53\u4e2d\u4e5f\u8574\u85cf\u7740\u98ce\u9669\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4eca\u5e74\u7f8e\u80a1\u7684\u5927\u725b\u80a1\u5f53\u4e2d\uff0c\u6295\u8d44\u8005\u4eec\u53d1\u73b0\u4e86\u4e24\u5bb6\u764c\u75c7\u836f\u7269\u5f00\u53d1\u516c\u53f8\u3002\u4ece2023\u5e74\u5e95\u52302024\u5e749\u670823\u65e5\u6536\u76d8\u4e3a\u6b62\uff0cSum [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":552601,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1521,430],"tags":[730,455,2155,925],"class_list":["post-552599","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1521","category-trends-strategies-zh-hans","tag-730","tag-455","tag-2155","tag-925","sectors-life-science-zh-hans","locations-china-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/552599","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=552599"}],"version-history":[{"count":1,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/552599\/revisions"}],"predecessor-version":[{"id":552609,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/552599\/revisions\/552609"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/552601"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=552599"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=552599"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=552599"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}