{"id":559093,"date":"2024-12-02T19:21:08","date_gmt":"2024-12-03T03:21:08","guid":{"rendered":"https:\/\/nai500.com\/?p=559093"},"modified":"2024-12-02T19:21:08","modified_gmt":"2024-12-03T03:21:08","slug":"%e9%ab%98%e4%bb%b7ai%e8%82%a1-%e9%ab%98%e4%bb%b7%e6%8a%97%e7%99%8c%e8%8d%af%e8%82%a1%e7%a5%a8-%e4%ba%bf%e4%b8%87%e5%af%8c%e7%bf%81%e6%a0%bc%e9%87%8c%e8%8a%ac","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2024\/12\/%e9%ab%98%e4%bb%b7ai%e8%82%a1-%e9%ab%98%e4%bb%b7%e6%8a%97%e7%99%8c%e8%8d%af%e8%82%a1%e7%a5%a8-%e4%ba%bf%e4%b8%87%e5%af%8c%e7%bf%81%e6%a0%bc%e9%87%8c%e8%8a%ac\/","title":{"rendered":"\u653e\u5f03\u4e00\u53ea\u9ad8\u4ef7AI\u80a1\uff0c\u62bc\u6ce8\u53e6\u4e00\u53ea\u9ad8\u4ef7\u6297\u764c\u836f\u80a1\u7968\uff0c\u4ebf\u4e07\u5bcc\u7fc1\u683c\u91cc\u82ac\u7684\u201c\u795e\u64cd\u4f5c\u201d"},"content":{"rendered":"

2022\u5e74\u5e95\u52302024\u5e7411\u67081\u65e5\uff0cAI\u6570\u636e\u6316\u6398\u4e13\u5bb6\u2014\u2014Palantir\uff08\u80a1\u7968\u4ee3\u7801\uff1aPLTR\uff09\u80a1\u4ef7\u66b4\u6da8\u4e86945%\u3002\u4e0d\u8fc7\uff0c\u6700\u65b0\u768413F\u5b63\u5ea6\u6301\u4ed3\u62a5\u544a\u663e\u793a\uff0c\u4ebf\u4e07\u5bcc\u7fc1\u80af\u00b7\u683c\u91cc\u82ac\uff08Ken Griffin\uff09\u7684\u5bf9\u51b2\u57fa\u91d1\u516c\u53f8Citadel\u5728\u7b2c\u4e09\u5b63\u5ea6\u603b\u8ba1\u629b\u552e\u7ea6520\u4e07\u80a1Palantir\u80a1\u7968\uff0c\u51cf\u630191%\uff0c\u8bf4\u660e\u683c\u91cc\u82ac\u5e76\u4e0d\u8ba4\u4e3a\u8fd9\u53eaAI\u5de8\u5934\u80a1\u7968\u7684\u725b\u5e02\u8fd8\u80fd\u7ee7\u7eed\u3002<\/p>\n

\u4e0e\u6b64\u540c\u65f6\uff0cCitadel\u5e76\u672a\u505c\u6b62\u5e03\u5c40\uff0c\u5b83\u5728\u7b2c\u4e09\u5b63\u5ea6\u5efa\u4ed3\u53e6\u4e00\u53ea\u540c\u6837\u80a1\u4ef7\u5927\u6da8\u7684\u80a1\u7968\uff1aSummit Therapeutics\uff08\u80a1\u7968\u4ee3\u7801\uff1aSMMT\uff09<\/a>\u3002\u8fd9\u662f\u4e00\u5bb6\u6b63\u5728\u7814\u53d1\u6297\u764c\u836f\u7269\u7684\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c2024\u5e74\u80a1\u4ef7\u5df2\u7ecf\u4e0a\u6da8\u8d85\u8fc7600%\u3002<\/p>\n

\u4e0e\u6b64\u540c\u65f6\uff0c\u534e\u5c14\u8857\u5206\u6790\u5e08\u4f9d\u7136\u975e\u5e38\u770b\u597d\u8fd9\u53ea\u6297\u764c\u836f\u80a1\u7968\uff0c\u6bd4\u5982\u8bf4H.C. Wainwright\u5206\u6790\u5e08Mitchell Kapoor\u6700\u8fd1\u7ed9\u51fa\u4e86\u6bcf\u80a144\u7f8e\u5143\u7684\u76ee\u6807\u4ef7\uff0c\u76f8\u8f83\u4e8e2024\u5e7411\u670829\u65e5\u7684\u6536\u76d8\u4ef7\uff0c\u80a1\u4ef7\u4e0a\u6da8\u7a7a\u95f4\u9ad8\u8fbe139%\u3002<\/p>\n

\u534e\u5c14\u8857\u4e3a\u4ec0\u4e48\u770b\u597dSummit Therapeutics\uff1f<\/h2>\n

Summit Therapeutics\u6b63\u5728\u5f00\u53d1Ivonescimab\uff08\u4f9d\u6c83\u897f\u5355\u6297\uff09\uff0c\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u80ba\u764c\u7684\u65b0\u836f\u3002Ivonescimab\u662f\u5eb7\u65b9\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684\u3001\u5168\u7403\u9996\u521bPD-1\/VEGF\u53cc\u7279\u5f02\u6027\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u836f\u7269\uff0c\u4eca\u5e745\u6708\u83b7\u5f97\u4e2d\u56fd\u76d1\u7ba1\u673a\u6784\u6279\u51c6\u4e0a\u5e02\uff0c\u8054\u5408\u5316\u7597\u7528\u4e8e\u7ecf\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff08EGFR-TKI\uff09\u6cbb\u7597\u8fdb\u5c55\u7684EGFR\u7a81\u53d8\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u9cde\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08nsq-NSCLC\uff09\u3002<\/p>\n

2024\u5e749\u6708\uff0c\u5eb7\u65b9\u751f\u7269\u516c\u5e03\u4e86\u4e00\u9879\u5728\u4e2d\u56fd\u8fdb\u884c\u7684\u5934\u5bf9\u5934\u8bd5\u9a8c\u4ee4\u4eba\u610f\u5916\u7684\u7ed3\u679c\uff0c\u5f15\u53d1\u884c\u4e1a\u70ed\u8bae\uff1a\u4e0e\u6807\u6746\u836f\u7269Keytruda\uff08\u5e15\u535a\u5229\u73e0\u5355\u6297\uff09\u76f8\u6bd4\uff0c\u65b0\u8bca\u65ad\u80ba\u764c\u60a3\u8005\u4f7f\u7528Ivonescimab\u7684\u75c5\u60c5\u6076\u5316\u6982\u7387\u964d\u4f4e\u4e8649%\u3002<\/p>\n

\u80ba\u764c\u662f\u5168\u7403\u6b7b\u4ea1\u7387\u6700\u9ad8\u7684\u6076\u6027\u80bf\u7624\uff0c\u5176\u53d1\u75c5\u7387\u4f4d\u5c45\u5168\u7403\u6076\u6027\u80bf\u7624\u53d1\u75c5\u7387\u7684\u7b2c\u4e8c\u4f4d\u3002\u5728\u6240\u6709\u80ba\u764c\u4e2d\uff0c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u5927\u7ea6\u536080%\u81f385%\u3002Keytruda\u867d\u7136\u6279\u51c6\u6cbb\u7597\u5341\u591a\u79cd\u4e0d\u540c\u7c7b\u578b\u7684\u764c\u75c7\uff0c\u4f46\u66f4\u591a\u7528\u4e8e\u6cbb\u7597\u4e00\u7ebf\u80ba\u764c\u60a3\u8005\u30022023\u5e74\uff0c\u8fd9\u6b3e\u836f\u7269\u7684\u9500\u552e\u989d\u8fbe\u5230250\u4ebf\u7f8e\u5143\u3002<\/p>\n

\u76ee\u524d\uff0cIvonescimab\u5c1a\u672a\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40 (FDA) \u7684\u6279\u51c6\u3002\u4e00\u65e6\u901a\u8fc7\u5ba1\u6279\uff0c\u5df2\u7ecf\u719f\u6089Keytruda\u7684\u80bf\u7624\u79d1\u533b\u751f\u5e94\u8be5\u4f1a\u66f4\u52a0\u5bb9\u6613\u63a5\u53d7Ivonescimab\u3002\u8fd9\u662f\u56e0\u4e3aKeytruda\u901a\u8fc7\u6291\u5236PD-1\u8def\u5f84\u6765\u589e\u5f3a\u514d\u75ab\u7cfb\u7edf\u5bf9\u5b9e\u4f53\u80bf\u7624\u7684\u653b\u51fb\uff0c\u800cIvonescimab\u662f\u4e00\u79cd\u53cc\u7279\u5f02\u6027\u6297\u4f53\uff0c\u80fd\u591f\u540c\u65f6\u6291\u5236PD-1\u548c\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50\uff08VEGF\uff09\u3002<\/p>\n

\u6b64\u5916\uff0cVEGF\u6291\u5236\u5242\uff08\u5982Avastin\uff09\u4e0ePD-1\u836f\u7269\uff08\u5982Keytruda\uff09\u7684\u8054\u5408\u4f7f\u7528\u5df2\u7ecf\u6210\u4e3a\u80bf\u7624\u6cbb\u7597\u7684\u5e38\u89c4\u505a\u6cd5\u3002\u56e0\u6b64\uff0c\u80bf\u7624\u79d1\u533b\u751f\u5bf9Ivonescimab\u7684\u63a5\u53d7\u5ea6\u53ef\u80fd\u4f1a\u6bd4\u4e00\u822c\u65b0\u836f\u66f4\u9ad8\u3002<\/p>\n

Ivonescimab\u548cSummit\u7684\u672a\u6765\u53d1\u5c55<\/h2>\n

Keytruda\u548cIvonescimab\u6210\u529f\u7684\u5934\u5bf9\u5934\u8bd5\u9a8c\u662f\u5728\u4e2d\u56fd\u8fdb\u884c\u7684\u3002\u4e3a\u4e86\u83b7\u5f97FDA\u7684\u6279\u51c6\uff0cSummit Therapeutics\u6b63\u5728\u7f8e\u56fd\u5f00\u5c55\u4e24\u9879III\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff1a<\/p>\n

    \n
  1. Harmoni\u8bd5\u9a8c\uff1a\u6d4b\u8bd5Ivonescimab\u8054\u5408\u6807\u51c6\u5316\u7597\u5bf9\u6bd4\u6807\u51c6\u5316\u7597\uff08\u52a0\u5b89\u6170\u5242\uff09\u5728\u4e8c\u7ebf\u60a3\u8005\u4e2d\u7684\u7597\u6548\u3002\u8be5\u7814\u7a76\u5df2\u5b8c\u6210\u60a3\u8005\u5165\u7ec4\uff0c\u9884\u8ba1\u5c06\u57282025\u5e74\u5e74\u4e2d\u63d0\u4f9b\u9876\u7ebf\u6570\u636e\u3002<\/li>\n
  2. Harmoni-3\u8bd5\u9a8c\uff1a\u6d4b\u8bd5Ivonescimab\u8054\u5408\u5316\u7597\u4e0eKeytruda\u8054\u5408\u5316\u7597\u5728\u65b0\u8bca\u65ad\u80ba\u764c\u60a3\u8005\u4e2d\u7684\u7597\u6548\u5bf9\u6bd4\u3002\u8fd9\u9879\u4e00\u7ebf\u6cbb\u7597\u8bd5\u9a8c\u4ecd\u5728\u62db\u52df\u60a3\u8005\uff0c\u9884\u8ba1\u8981\u52302027\u5e74\u624d\u80fd\u83b7\u5f97\u9876\u7ebf\u7ed3\u679c\u3002\u8fd9\u9879\u7814\u7a76\u5bf9Summit\u7684\u6295\u8d44\u8005\u6765\u8bf4\u66f4\u4e3a\u91cd\u8981\uff0c\u56e0\u4e3a\u65b0\u8bca\u65ad\u60a3\u8005\u7684\u6cbb\u7597\u5468\u671f\u901a\u5e38\u6bd4\u590d\u53d1\u60a3\u8005\u66f4\u957f\u3002<\/li>\n<\/ol>\n

    \u73b0\u5728\u8be5\u4e70\u5417\uff1f<\/h2>\n

    Harmoni\u8bd5\u9a8c\u7684\u79ef\u6781\u7ed3\u679c\u53ef\u80fd\u4f1a\u63a8\u52a8Summit Therapeutics\u7684\u80a1\u4ef7\u5728\u671f\u5f85Harmoni-3\u6210\u529f\u7684\u6c1b\u56f4\u4e2d\u518d\u6b21\u98d9\u5347\u3002\u7136\u800c\uff0c\u76ee\u524d\u8fd9\u53ea\u80a1\u7968\u7684\u4ef7\u683c\u5df2\u7ecf\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u53cd\u6620\u4e86\u5e02\u573a\u7684\u6210\u529f\u9884\u671f\u3002\u622a\u81f32024\u5e7411\u6708\u5e95\uff0c\u8be5\u516c\u53f8\u5e02\u503c\u5df2\u9ad8\u8fbe136\u4ebf\u7f8e\u5143\u3002\u5bf9\u4e8e\u4e00\u5bb6\u8fd8\u672a\u62e5\u6709\u4efb\u4f55\u4e0a\u5e02\u4ea7\u54c1\u7684\u516c\u53f8\u6765\u8bf4\uff0c\u8fd9\u4e00\u4f30\u503c\u76f8\u5f53\u60ca\u4eba\u3002<\/p>\n

    \u867d\u7136Ivonescimab\u6709\u671b\u6210\u4e3a\u4e00\u7ebf\u80ba\u764c\u6cbb\u7597\u7684\u70ed\u95e8\u9009\u62e9\uff0c\u4f46Summit\u81f3\u5c11\u8981\u52302026\u5e74\u521d\u624d\u53ef\u80fd\u62e5\u6709\u7a33\u5b9a\u7684\u6536\u5165\u6765\u6e90\u3002\u5982\u679c\u660e\u5e74Harmoni\u8bd5\u9a8c\u7684\u6570\u636e\u65e0\u6cd5\u4ee4\u6295\u8d44\u8005\u6ee1\u610f\uff0c\u90a3\u4e48\u4ee5\u76ee\u524d\u9ad8\u4f30\u503c\u4e70\u5165\u7684\u6295\u8d44\u8005\u53ef\u80fd\u4f1a\u9762\u4e34\u5de8\u5927\u7684\u635f\u5931\u3002\u5bf9\u4e8e\u62e5\u6709\u8d85\u9ad8\u98ce\u9669\u627f\u53d7\u80fd\u529b\u7684\u4ebf\u4e07\u5bcc\u7fc1\u6295\u8d44\u8005\u6765\u8bf4\uff0c\u62bc\u6ce8Summit Therapeutics\u6216\u8bb8\u53ef\u4ee5\u7406\u89e3\u3002\u4f46\u5bf9\u5927\u591a\u6570\u666e\u901a\u6295\u8d44\u8005\u6765\u8bf4\uff0c\u98ce\u9669\u8fc7\u9ad8\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

    2022\u5e74\u5e95\u52302024\u5e7411\u67081\u65e5\uff0cAI\u6570\u636e\u6316\u6398\u4e13\u5bb6\u2014\u2014Palantir\uff08\u80a1\u7968\u4ee3\u7801\uff1aPLTR\uff09\u80a1\u4ef7\u66b4\u6da8\u4e86945 […]<\/p>\n","protected":false},"author":27,"featured_media":550430,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1521,430],"tags":[455,2125,925],"class_list":["post-559093","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1521","category-trends-strategies-zh-hans","tag-455","tag-2125","tag-925","sectors-life-science-zh-hans","sectors-technology-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/559093","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=559093"}],"version-history":[{"count":1,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/559093\/revisions"}],"predecessor-version":[{"id":559103,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/559093\/revisions\/559103"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/550430"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=559093"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=559093"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=559093"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}