{"id":560778,"date":"2024-12-17T19:11:31","date_gmt":"2024-12-18T03:11:31","guid":{"rendered":"https:\/\/nai500.com\/?p=560778"},"modified":"2024-12-17T19:11:31","modified_gmt":"2024-12-18T03:11:31","slug":"2025-%e5%b9%b4%e5%8f%af%e8%83%bd%e9%a3%99%e5%8d%87%e7%9a%84-2-%e5%8f%aa%e6%88%90%e9%95%bf%e8%82%a1%e5%ae%83%e4%bb%ac%e9%80%82%e5%90%88%e6%82%a8%e5%90%97","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2024\/12\/2025-%e5%b9%b4%e5%8f%af%e8%83%bd%e9%a3%99%e5%8d%87%e7%9a%84-2-%e5%8f%aa%e6%88%90%e9%95%bf%e8%82%a1%e5%ae%83%e4%bb%ac%e9%80%82%e5%90%88%e6%82%a8%e5%90%97\/","title":{"rendered":"2025\u5e74\u53ef\u80fd\u98d9\u5347\u76842\u53ea\u6210\u957f\u80a1\uff1a\u5b83\u4eec\u9002\u5408\u60a8\u5417\uff1f"},"content":{"rendered":"

\u5bf9\u4e8e\u5bfb\u6c42\u6536\u76ca\u7684\u6295\u8d44\u8005\u6765\u8bf4\uff0c\u751f\u7269\u5236\u836f\u884c\u4e1a\u4e2d\u7684\u67d0\u4e9b\u80a1\u7968\u53ef\u80fd\u4f1a\u5927\u5e45\u4e0a\u5347\u3002\u76ee\u524d\uff0c\u534e\u5c14\u8857\u9884\u8ba1\u6709\u4e24\u53ea\u751f\u7269\u5236\u836f\u80a1\u7968\u5c06\u57282025\u5e74\u98d9\u5347\u3002<\/p>\n

\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40(FDA)\u53bb\u5e7412\u6708\u6279\u51c6\u4e86CRISPR Therapeutics (CRSP)<\/a>\u7684\u9996\u4e2a\u6cbb\u7597\u65b9\u6cd5\uff0c\u53ef\u80fd\u4f1a\u63a8\u52a8\u80a1\u4ef7\u5927\u5e45\u4e0a\u6da8\u3002\u6295\u8d44\u94f6\u884c\u5206\u6790\u5e08\u8fd8\u9884\u8ba1Iovance Biotherapeutics (IOVA)<\/a>\u80a1\u4ef7\u5c06\u57282025\u5e74\u98d9\u5347\u3002<\/p>\n

\u4e0d\u8fc7\uff0c\u5728\u8ffd\u9010\u4ee4\u4eba\u5174\u594b\u7684\u4ef7\u683c\u76ee\u6807\u4e4b\u524d\uff0c\u91cd\u8981\u7684\u662f\u8981\u8bb0\u4f4f\uff0c\u5982\u679c\u4e8b\u60c5\u6ca1\u6709\u6210\u529f\uff0c\u8bbe\u5b9a\u9ad8\u671f\u671b\u7684\u5206\u6790\u5e08\u53ef\u4ee5\u6084\u6084\u4e0b\u8c03\u671f\u671b\u3002\u8ba9\u6211\u4eec\u6765\u770b\u770b\u8fd9\u4e9b\u6210\u957f\u80a1\u9884\u8ba1\u4f1a\u98d9\u5347\u7684\u4e00\u4e9b\u539f\u56e0\uff0c\u5e76\u8003\u8651\u5b83\u4eec\u662f\u5426\u9002\u5408\u60a8\u7684\u6295\u8d44\u7ec4\u5408\u3002<\/p>\n

CRISPR Therapeutics<\/h2>\n

CRISPR Therapeutics\u7684\u80a1\u7968\u5df2\u4ece2\u6708\u4efd\u7684\u5cf0\u503c\u4e0b\u8dcc\u4e86\u7ea651%\u3002\u5173\u6ce8\u8fd9\u5bb6\u57fa\u56e0\u6cbb\u7597\u5f00\u53d1\u5546\u7684\u534e\u5c14\u8857\u5206\u6790\u5e08\u9884\u8ba1\u80a1\u4ef7\u4f1a\u53cd\u5f39\u3002\u8be5\u80a1\u7684\u5e73\u5747\u76ee\u6807\u4ef7\u610f\u5473\u7740\u8be5\u80a1\u5728\u672a\u676512\u4e2a\u6708\u5c06\u4e0a\u6da882%\u3002<\/p>\n

CRISPR Therapeutics\u80a1\u4ef7\u572811\u6708\u7b2c\u4e09\u8d22\u5b63\u62a5\u544a\u53d1\u5e03\u540e\u4e0b\u6ed1\u3002Casgevy\u662f\u4e00\u79cd\u5355\u6b21\u6cbb\u7597\u9570\u72b6\u7ec6\u80de\u75c5\u548c\u03b2-\u5730\u4e2d\u6d77\u8d2b\u8840\u7684\u836f\u7269\uff0c\u53bb\u5e7412\u6708\u83b7\u5f97\u4e86FDA\u6279\u51c6\uff0c\u4f46CRISPR\u53ca\u5176\u5408\u4f5c\u4f19\u4f34Vertex Pharmaceuticals<\/a>\u4ecd\u672a\u4ece\u4e2d\u83b7\u5f97\u53ef\u89c2\u7684\u6536\u5165\u3002\u4ee5\u6bcf\u4f4d\u60a3\u8005\u7ea6220\u4e07\u7f8e\u5143\u7684\u6807\u4ef7\uff0cCasgevy\u4e0d\u9700\u8981\u5f88\u591a\u6cbb\u7597\u6570\u91cf\u5c31\u80fd\u4ea7\u751f\u53ef\u89c2\u7684\u6536\u5165\u6765\u6e90\u3002<\/p>\n

CRISPR\u7ba1\u7ebf\u4e2d\u53ef\u80fd\u51fa\u73b0\u7684\u4e0b\u4e00\u79cd\u7597\u6cd5\u53ef\u80fd\u66f4\u5bb9\u6613\u9500\u552e\u3002\u5019\u9009\u836f\u7269CTX112\u662f\u4e00\u79cd\u73b0\u6210\u7684\u7ec6\u80de\u6dcb\u5df4\u7624\u7597\u6cd5\uff0c\u6700\u8fd1\u57281\/2\u671f\u8bd5\u9a8c\u4e2d\u4ea7\u751f\u4e86\u4e00\u4e9b\u4ee4\u4eba\u4fe1\u670d\u7684\u6570\u636e\u3002\u5728\u63a5\u53d7\u56db\u6b21\u9012\u589e\u5242\u91cf\u6cbb\u7597\u768412\u540d\u60a3\u8005\u4e2d\uff0c\u67096\u540d\u60a3\u8005\u5b8c\u5168\u7f13\u89e3\uff0c\u53e6\u5916\u4e24\u540d\u60a3\u8005\u7684\u80bf\u7624\u4e5f\u56e0\u6cbb\u7597\u800c\u7f29\u5c0f\u3002\u4e00\u534a\u60a3\u8005\u7684\u764c\u75c7\u5728\u6700\u521d\u53cd\u5e94\u516d\u4e2a\u6708\u540e\u4ecd\u672a\u6076\u5316\u3002<\/p>\n

Iovance Biotherapeutics<\/h2>\n

Iovance Biotherapeutics\u7684\u80a1\u4ef7\u5df2\u4ece2\u6708\u4efd\u7684\u5cf0\u503c\u4e0b\u8dcc\u4e86\u7ea655%\uff0c\u4f46\u5173\u6ce8\u8be5\u80a1\u7684\u5206\u6790\u5e08\u9884\u8ba1\u8be5\u80a1\u57282025\u5e74\u5c06\u51fa\u73b0\u5927\u5e45\u53cd\u5f39\u3002\u4ed6\u4eec\u7684\u4e00\u81f4\u76ee\u6807\u4ef7\u4e3a23.77\u7f8e\u5143\uff0c\u610f\u5473\u7740\u8be5\u80a1\u672a\u676512\u4e2a\u6708\u5c06\u4e0a\u6da8204%\u3002<\/p>\n

\u4eca\u5e742\u6708\uff0c\u8be5\u516c\u53f8\u9996\u6b21\u83b7\u5f97Amtagvi\u836f\u7269\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u9ed1\u8272\u7d20\u7624\u3002Amtagvi\u7684\u9996\u6b21\u4e0a\u5e02\u53d6\u5f97\u4e86\u6210\u529f\u3002\u7b2c\u4e09\u8d22\u5b63\u7684\u9500\u552e\u989d\u8fbe\u5230\u4e86\u5e74\u53162.34\u4ebf\u7f8e\u5143\uff0c\u800c\u4e14\u8fd8\u5728\u5feb\u901f\u589e\u957f\u3002\u7ba1\u7406\u5c42\u9884\u8ba12025\u5e74\u7684\u9500\u552e\u989d\u5c06\u57284.5\u4ebf\u81f34.75\u4ebf\u7f8e\u5143\u4e4b\u95f4\u3002<\/p>\n

\u9664\u4e86\u5168\u7403\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u5916\uff0cAmtagvi\u8fd8\u53ef\u80fd\u6210\u4e3a\u4e00\u79cd\u8f70\u52a8\u7684\u80ba\u764c\u6cbb\u7597\u836f\u7269\u3002\u8be5\u836f\u7269\u6b63\u5728\u80ba\u764c\u60a3\u8005\u4e2d\u8fdb\u884c2\u671f\u8bd5\u9a8c\u3002\u7814\u7a76\u7ed3\u679c\u9884\u8ba1\u5c06\u4e8e2025\u5e74\u516c\u5e03\uff0c\u53ef\u80fd\u4f1a\u63a8\u52a8\u8be5\u80a1\u98d9\u5347\u3002<\/p>\n

Iovance\u80a1\u4ef7\u4f3c\u4e4e\u88ab\u4f4e\u4f30\u4e86\uff0c\u8be5\u516c\u53f8\u7684\u5e02\u503c\u5df2\u964d\u81f3\u7ea624\u4ebf\u7f8e\u5143\u3002\u5982\u679c\u8fd9\u79cd\u7597\u6cd5\u5982\u9884\u671f\u7684\u90a3\u6837\u5728\u6b27\u76df\u83b7\u5f97\u6279\u51c6\uff0c\u5e74\u9500\u552e\u989d\u53ef\u80fd\u5728\u77ed\u77ed\u51e0\u5e74\u5185\u8d85\u8fc710\u4ebf\u7f8e\u5143\u3002<\/p>\n

\u662f\u65f6\u5019\u4e70\u5165\u8fd9\u4e9b\u80a1\u7968\u4e86\u5417\uff1f<\/h2>\n

\u5728\u6295\u8d44Iovance\u4e4b\u524d\uff0c\u91cd\u8981\u7684\u662f\u8981\u8bb0\u4f4f\uff0c\u653f\u5e9c\u76d1\u7ba1\u673a\u6784\u5e76\u4e0d\u5173\u5fc3\u516c\u53f8\u80a1\u4ef7\u3002\u5982\u679c\u60a8\u7684\u98ce\u9669\u627f\u53d7\u80fd\u529b\u4e0d\u8db3\u4ee5\u5e94\u5bf9\u6b27\u6d32\u76d1\u7ba1\u673a\u6784\u6279\u8bc4Amtagvi\u5bfc\u81f4\u7684\u80a1\u4ef7\u4e0b\u8dcc\uff0c\u90a3\u4e48\u60a8\u5e94\u8be5\u8896\u624b\u65c1\u89c2\u3002<\/p>\n

Casgevy\u662f\u9996\u4e2a\u83b7\u6279\u4f7f\u7528\u57fa\u4e8eCRISPR\u7684\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6cbb\u7597\u9570\u72b6\u7ec6\u80de\u75c5\u548c\u03b2-\u5730\u4e2d\u6d77\u8d2b\u8840\u7684\u57fa\u56e0\u7597\u6cd5\uff0c\u4f46\u5b83\u5e76\u975e\u662f\u8fd9\u4e9b\u60a3\u8005\u7fa4\u4f53\u7684\u552f\u4e00\u9009\u62e9\u3002Bluebird Bio<\/a>\u7684\u57fa\u56e0\u7597\u6cd5Zynteglo\u548cLyfgenia\u6700\u8fd1\u5206\u522b\u83b7\u5f97\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u03b2-\u5730\u4e2d\u6d77\u8d2b\u8840\u548c\u9570\u72b6\u7ec6\u80de\u75c5\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5bf9\u4e8e\u5bfb\u6c42\u6536\u76ca\u7684\u6295\u8d44\u8005\u6765\u8bf4\uff0c\u751f\u7269\u5236\u836f\u884c\u4e1a\u4e2d\u7684\u67d0\u4e9b\u80a1\u7968\u53ef\u80fd\u4f1a\u5927\u5e45\u4e0a\u5347\u3002\u76ee\u524d\uff0c\u534e\u5c14\u8857\u9884\u8ba1\u6709\u4e24\u53ea\u751f\u7269\u5236\u836f\u80a1\u7968\u5c06\u5728202 […]<\/p>\n","protected":false},"author":9,"featured_media":560779,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[427],"tags":[820,455,747,925],"class_list":["post-560778","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hans","tag-820","tag-455","tag-747","tag-925","sectors-life-science-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans","exchange-nyse-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/560778","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=560778"}],"version-history":[{"count":1,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/560778\/revisions"}],"predecessor-version":[{"id":560786,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/560778\/revisions\/560786"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/560779"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=560778"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=560778"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=560778"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}