{"id":571010,"date":"2025-04-06T23:18:39","date_gmt":"2025-04-07T06:18:39","guid":{"rendered":"https:\/\/nai500.com\/?p=571010"},"modified":"2025-04-06T23:18:39","modified_gmt":"2025-04-07T06:18:39","slug":"%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%b5%9b%e9%81%93%e5%b4%9b%e8%b5%b7%ef%bc%81%e4%b8%83%e5%a4%a7%e6%bd%9c%e5%8a%9b%e8%82%a1%e8%8e%b7%e6%9c%ba%e6%9e%84%e5%8a%9b%e6%8d%a7","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2025\/04\/%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%b5%9b%e9%81%93%e5%b4%9b%e8%b5%b7%ef%bc%81%e4%b8%83%e5%a4%a7%e6%bd%9c%e5%8a%9b%e8%82%a1%e8%8e%b7%e6%9c%ba%e6%9e%84%e5%8a%9b%e6%8d%a7\/","title":{"rendered":"\u57fa\u56e0\u7f16\u8f91\u8d5b\u9053\u5d1b\u8d77\uff01\u4e03\u5927\u6f5c\u529b\u80a1\u83b7\u673a\u6784\u529b\u6367"},"content":{"rendered":"<p>\u57fa\u56e0\u7597\u6cd5\u4e0e\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6b63\u5f15\u9886\u73b0\u4ee3\u751f\u7269\u79d1\u6280\u9769\u547d\u3002\u57fa\u56e0\u7597\u6cd5\u901a\u8fc7\u7ec6\u80de\u5c42\u9762\u7684\u57fa\u56e0\u4fee\u6b63\u6cbb\u7597\u9057\u4f20\u7f3a\u9677\uff0c\u800c\u57fa\u56e0\u7f16\u8f91\u66f4\u8fdb\u4e00\u6b65\uff0c\u76f4\u63a5\u4fee\u6539\u57fa\u56e0\u7ec4\u5b9e\u73b0\u75be\u75c5\u6cbb\u7597\u3002Precedence Research\u9884\u6d4b\uff0c\u57fa\u56e0\u7f16\u8f91\u5e02\u573a\u6bcf\u5e74\u5c06\u4ee515.7%\u7684\u901f\u5ea6\u6269\u5f20\uff0c\u52302034\u5e74\u5c06\u8fbe\u5230401\u4ebf\u7f8e\u5143\uff0c\u8fd9\u4e5f\u610f\u5473\u7740\u7f8e\u80a1\u7684\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u5c06\u8fce\u6765\u957f\u671f\u6295\u8d44\u673a\u9047\u3002<\/p>\n<p>\u4e3a\u4e86\u5e2e\u52a9\u6295\u8d44\u8005\u9009\u80a1\uff0c\u7f8e\u56fd\u94f6\u884c\u8fd1\u65e5\u7b5b\u9009\u51fa\u57fa\u56e0\u7f16\u8f91\u80a1\u7968\u7684\u4e03\u5927\u6f5c\u529b\u6807\u7684\uff1a<\/p>\n<ol>\n<li><strong><a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=LLY\">\u793c\u6765\uff08LLY\uff09<\/a><\/strong><\/li>\n<\/ol>\n<p><strong>\u80a1\u4ef7\u4e0a\u6da8\u6f5c\u529b\uff1a22.2%<\/strong><\/p>\n<p>\u793c\u6765\u4e13\u6ce8\u7cd6\u5c3f\u75c5\u3001\u764c\u75c7\u53ca\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u836f\u7269\u7814\u53d1\uff0c\u8fd1\u5e74\u52a0\u7801\u57fa\u56e0\u6cbb\u7597\u5408\u4f5c\uff0c\u5305\u62ec2023\u5e7410\u6708\u83b7\u5f97Beam Therapeutics\u5fc3\u8840\u7ba1\u75be\u75c5\u78b1\u57fa\u7f16\u8f91\u7597\u6cd5\u7684\u4f18\u5148\u6743\u3002\u7f8e\u94f6\u5206\u6790\u5e08Tim Anderson\u6307\u51fa\uff0cGLP-1\u51cf\u91cd\u836f\u7269\u7ba1\u7ebf\u5c06\u9a71\u52a8\u516c\u53f8\u957f\u671f\u589e\u957f\uff0c\u56e0\u6b64\u7ed9\u4e88\u8be5\u80a1&#8221;\u4e70\u5165&#8221;\u8bc4\u7ea7\uff0c\u76ee\u6807\u4ef71000\u7f8e\u5143\uff084\u67082\u65e5\u6536\u76d8\u4ef7818.22\u7f8e\u5143\uff0c\u4e0b\u540c\uff09\u3002<\/p>\n<ol start=\"2\">\n<li><strong>\u8d5b\u8bfa\u83f2\uff08SNY\uff09<\/strong><\/li>\n<\/ol>\n<p><strong>\u80a1\u4ef7\u4e0a\u6da8\u6f5c\u529b\uff1a146.6%<\/strong><\/p>\n<p>\u8fd9\u5bb6\u6cd5\u56fd\u836f\u4f01\u6df1\u8015\u8fc7\u654f\u3001\u80bf\u7624\u53ca\u7f55\u89c1\u75c5\u9886\u57df\uff0c\u6838\u5fc3\u4ea7\u54c1\u5305\u62ec\u7cd6\u5c3f\u75c5\u836f\u7269Lantus\u548c\u6297\u708e\u836fDupixent\u30022023\u5e74\uff0c\u8d5b\u8bfa\u83f2\u4e0eScribe Therapeutics\u6269\u5927\u5408\u4f5c\uff0c\u5229\u7528CRISPR\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u5f00\u53d1\u764c\u75c7\u7ec6\u80de\u7597\u6cd5\u3002\u5206\u6790\u5e08Graham Parry\u8ba4\u4e3a\uff0c\u521b\u65b0\u7ba1\u7ebf\u53ca2029\u5e74\u524d12%\u7684\u5e74\u6536\u76ca\u589e\u901f\u652f\u6491\u4f30\u503c\u4fee\u590d\u7a7a\u95f4\u3002\u7f8e\u94f6\u7ed9\u4e88\u8be5\u80a1\u201c\u4e70\u5165\u201d\u8bc4\u7ea7\uff0c\u76ee\u6807\u4ef7133.06\u7f8e\u5143\uff08\u6536\u76d8\u4ef753.95\u7f8e\u5143\uff09\u3002<\/p>\n<ol start=\"3\">\n<li><strong>Vertex Pharmaceuticals\uff08VRTX\uff09<\/strong><\/li>\n<\/ol>\n<p><strong>\u80a1\u4ef7\u4e0a\u6da8\u6f5c\u529b\uff1a14.8%<\/strong><\/p>\n<p>Vertex\u4ee5\u56ca\u6027\u7ea4\u7ef4\u5316\u7597\u6cd5\u95fb\u540d\uff0c\u5e76\u4eab\u6709CRISPR\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5Casgevy 60%\u7684\u9500\u552e\u5229\u6da6\u5206\u6210\u3002\u8be5\u7597\u6cd5\u5df2\u83b7FDA\u6279\u51c6\u6cbb\u7597\u9570\u72b6\u7ec6\u80de\u75c5\u548c\u8f93\u8840\u4f9d\u8d56\u578b\u03b2\u5730\u4e2d\u6d77\u8d2b\u8840\uff0c2024\u5e74\u5e95\u516c\u5e03\u7684\u957f\u671f\u6570\u636e\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u7597\u6548\u3002\u5206\u6790\u5e08Tazeen Ahmad\u5f3a\u8c03Casgevy\u7684\u5168\u7403\u5316\u63a8\u5e7f\u6b63\u5728\u7a33\u6b65\u63a8\u8fdb\u3002\u7f8e\u94f6\u76ee\u6807\u4ef7555\u7f8e\u5143\uff08\u6536\u76d8\u4ef7483.49\u7f8e\u5143\uff09\u3002<\/p>\n<ol start=\"4\">\n<li><strong>CRISPR Therapeutics\uff08CRSP\uff09<\/strong><\/li>\n<\/ol>\n<p><strong>\u80a1\u4ef7\u4e0a\u6da8\u6f5c\u529b\uff1a151.5%<\/strong><\/p>\n<p>\u51ed\u501fCRISPR-Cas9\u6280\u672f\u5f00\u53d1\u8840\u6db2\u75c5\u53ca\u80bf\u7624\u7597\u6cd5\uff0cCasgevy\u867d\u5df2\u4e0a\u5e02\uff0c\u4f46\u80a1\u4ef7\u8fd1\u4e00\u5e74\u8dcc\u5e45\u8d8544%\u3002\u5206\u6790\u5e08Alec Stranahan\u6307\u51fa\uff0cCTX112\u7ec6\u80de\u7597\u6cd5\u5728\u80bf\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u75c5\u8bd5\u9a8c\u4e2d\u8868\u73b0\u4eae\u773c\uff0c\u672a\u6765Casgevy\u7684\u9500\u552e\u989d\u589e\u957f\u4ee5\u53caCTX310\/320\u7684\u6570\u636e\u6216\u6210\u5173\u952e\u50ac\u5316\u5242\u3002\u7f8e\u94f6\u76ee\u6807\u4ef71216\u7f8e\u5143\uff08\u6536\u76d8\u4ef7483.49\u7f8e\u5143\uff09\u3002<\/p>\n<ol start=\"5\">\n<li><strong>Intellia Therapeutics\uff08NTLA\uff09<\/strong><\/li>\n<\/ol>\n<p><strong>\u80a1\u4ef7\u4e0a\u6da8\u6f5c\u529b\uff1a489.0%<\/strong><\/p>\n<p>\u8fd9\u5bb6\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u79d1\u6280\u516c\u53f8\u805a\u7126\u4f53\u5185\u5916\u7684CRISPR-Cas9\u57fa\u56e0\u7f16\u8f91\u4ea7\u54c1\uff0c\u6838\u5fc3\u7ba1\u7ebfNex-z\u9488\u5bf9\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\u6dc0\u7c89\u6837\u53d8\u6027\uff0c\u53e6\u6709\u9057\u4f20\u6027\u8840\u7ba1\u6c34\u80bf\u7597\u6cd5NTLA-2002\u5904\u4e8e\u540e\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002Stranahan\u9884\u8ba1Intellia\u7684\u73b0\u91d1\u6d41\u53ef\u652f\u6491\u52302027\u5e74\u4e0a\u534a\u5e74\uff0c2030\u5e74\u524d\u6216\u6709\u4e09\u6b3e\u836f\u7269\u4e0a\u5e02\u3002\u7f8e\u94f6\u76ee\u6807\u4ef743\u7f8e\u5143\uff08\u6536\u76d8\u4ef77.30\u7f8e\u5143\uff09\u3002<\/p>\n<ol start=\"6\">\n<li><strong>Sana Biotechnology\uff08SANA\uff09<\/strong><\/li>\n<\/ol>\n<p><strong>\u80a1\u4ef7\u4e0a\u6da8\u6f5c\u529b\uff1a329.4%<\/strong><\/p>\n<p>Sana\u81f4\u529b\u4e8e\u5f00\u53d1&#8221;\u7ec6\u80de\u836f\u7269&#8221;\uff0c\u516c\u53f8\u7684\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u53ef\u5c4f\u853d\u60a3\u8005\u5bf9\u6cbb\u7597\u7ec6\u80de\u7684\u514d\u75ab\u6392\u65a5\u3002\u7ec6\u80de\u7597\u6cd5SC451\u5355\u6b21\u6cbb\u7597\u5c31\u80fd\u6cbb\u6108\u80f0\u5c9b\u7d20\u4f9d\u8d56\u578b\u4e00\u578b\u7cd6\u5c3f\u75c5\uff0c\u53e6\u6709\u4e24\u6b3e\u5f02\u4f53CAR-T\u7597\u6cd5\u8fdb\u5165\u540e\u671f\u4e34\u5e8a\u3002\u7f8e\u94f6\u76ee\u6807\u4ef77\u7f8e\u5143\uff08\u6536\u76d8\u4ef71.63\u7f8e\u5143\uff09\u3002<\/p>\n<ol start=\"7\">\n<li><strong>Caribou Biosciences\uff08CRBU\uff09<\/strong><\/li>\n<\/ol>\n<p><strong>\u80a1\u4ef7\u4e0a\u6da8\u6f5c\u529b\uff1a1177.6%<\/strong><\/p>\n<p>\u4e13\u6ce8\u901a\u7528\u578b\u7ec6\u80de\u7597\u6cd5\uff0c\u516c\u53f8\u80a1\u4ef7\u867d\u56e0CB-020\u6682\u505c\u5f00\u53d1\u800c\u53d7\u632b\uff0c\u4f46\u6838\u5fc3\u7ba1\u7ebfCB-010\/011\/012\u4ecd\u5728\u63a8\u8fdb\u3002\u5206\u6790\u5e08\u8ba4\u4e3a\uff0c2025\u5e74\u79ef\u6781\u7684\u6570\u636e\u6216\u91cd\u71c3\u5e02\u573a\u4fe1\u5fc3\uff0c\u800c7. Caribou\u7684\u73b0\u91d1\u6d41\u53ef\u7ef4\u6301\u81f32026\u5e74\u4e0b\u534a\u5e74\u3002\u7f8e\u94f6\u76ee\u6807\u4ef711\u7f8e\u5143\uff08\u6536\u76d8\u4ef70.86\u7f8e\u5143\uff09\u3002<\/p>\n<p>\u7f8e\u94f6\u5f3a\u8c03\uff0c\u57fa\u56e0\u7f16\u8f91\u9886\u57df\u6280\u672f\u7a81\u7834\u9891\u73b0\uff0c\u4e0a\u8ff0\u4f01\u4e1a\u51ed\u501f\u5dee\u5f02\u5316\u7ba1\u7ebf\u4e0e\u4e34\u5e8a\u8fdb\u5c55\uff0c\u6709\u671b\u5728\u957f\u671f\u7ade\u4e89\u4e2d\u5360\u636e\u5148\u673a\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u57fa\u56e0\u7597\u6cd5\u4e0e\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6b63\u5f15\u9886\u73b0\u4ee3\u751f\u7269\u79d1\u6280\u9769\u547d\u3002\u57fa\u56e0\u7597\u6cd5\u901a\u8fc7\u7ec6\u80de\u5c42\u9762\u7684\u57fa\u56e0\u4fee\u6b63\u6cbb\u7597\u9057\u4f20\u7f3a\u9677\uff0c\u800c\u57fa\u56e0\u7f16\u8f91\u66f4\u8fdb\u4e00\u6b65\uff0c [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":571011,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1521,430],"tags":[455,747,925,1997],"class_list":["post-571010","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1521","category-trends-strategies-zh-hans","tag-455","tag-747","tag-925","tag-1997","sectors-life-science-zh-hans","locations-europe-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans","exchange-nyse-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/571010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=571010"}],"version-history":[{"count":2,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/571010\/revisions"}],"predecessor-version":[{"id":571019,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/571010\/revisions\/571019"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/571011"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=571010"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=571010"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=571010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}