{"id":594267,"date":"2025-09-22T06:21:44","date_gmt":"2025-09-22T13:21:44","guid":{"rendered":"https:\/\/nai500.com\/?p=594267"},"modified":"2025-09-22T06:21:44","modified_gmt":"2025-09-22T13:21:44","slug":"pfizer-pfe-metsera-mtsr-49-cvr","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2025\/09\/pfizer-pfe-metsera-mtsr-49-cvr\/","title":{"rendered":"Pfizer (PFE) \u6536\u8d2d Metsera (MTSR)\uff0c\u4ea4\u6613\u4ef7\u4e3a 49 \u4ebf\u7f8e\u5143\u5e76\u542b\u6709 CVR"},"content":{"rendered":"

Pfizer \u5c06\u4ee5 49 \u4ebf\u7f8e\u5143\u73b0\u91d1\u6536\u8d2d Metsera\uff0c\u652f\u4ed8\u6bcf\u80a1 47.50 \u7f8e\u5143\uff0c\u5e76\u6839\u636e\u4e34\u5e8a\u548c\u76d1\u7ba1\u91cc\u7a0b\u7891\u6700\u591a\u989d\u5916\u652f\u4ed8\u6bcf\u80a1 22.50 \u7f8e\u5143\u3002\u8be5\u4ea4\u6613\u8f83 Metsera \u4e0a\u4e00\u4ea4\u6613\u65e5\u6536\u76d8\u4ef7\u63d0\u4f9b 43% \u6ea2\u4ef7\uff0c\u5e76\u5728\u6240\u6709\u91cc\u7a0b\u7891\u8fbe\u6210\u60c5\u51b5\u4e0b\u5c06\u8fd9\u5bb6\u6297\u80a5\u80d6\u836f\u7269\u5f00\u53d1\u5546\u7684\u4f30\u503c\u63d0\u9ad8\u5230\u6700\u591a 72 \u4ebf\u7f8e\u5143\u3002Metsera \u80a1\u4ef7\u5728\u76d8\u524d\u98d9\u5347\u8fd1 60%\uff0c\u800c Pfizer \u4e0a\u6da8\u7ea6 2%\uff0c\u8868\u660e\u6295\u8d44\u8005\u66f4\u9752\u7750\u4ee5\u73b0\u91d1\u8d2d\u5f97\u7684\u5728\u7814\u7ba1\u7ebf\uff0c\u800c\u975e\u5728 Pfizer \u81ea\u8eab\u51cf\u91cd\u9879\u76ee\u505c\u6ede\u540e\u8fdb\u884c\u7684\u5185\u90e8\u91cd\u7ec4\u3002<\/p>\n

\u5e02\u573a\u53cd\u5e94<\/h3>\n

\u4ea4\u6613\u8005\u53cd\u5e94\u8fc5\u901f\u3002Metsera \u56e0\u5934\u6761\u6ea2\u4ef7\u4ee5\u53ca\u82e5\u5176\u9879\u76ee\u63a8\u8fdb\u5c06\u83b7\u5f97\u989d\u5916\u652f\u4ed8\u7684\u660e\u786e\u8def\u5f84\u800c\u5927\u5e45\u4e0a\u6da8\u3002Pfizer \u7684\u65e9\u76d8\u6da8\u5e45\u867d\u6e29\u548c\u4f46\u503c\u5f97\u5173\u6ce8\uff0c\u5bf9\u4e8e\u4e00\u53ea\u5728\u4eca\u5e74\u65e9\u4e9b\u65f6\u5019\u56e0 danuglipron \u809d\u6bd2\u6027\u95ee\u9898\u505c\u4ea7\u540e\u96be\u4ee5\u8bf4\u670d\u6295\u8d44\u8005\u5176\u5728\u80a5\u80d6\u9886\u57df\u6709\u53ef\u4fe1\u7b56\u7565\u7684\u5de8\u5934\u6765\u8bf4\uff0c\u8fd9\u4e00\u53cd\u5e94\u5f88\u91cd\u8981\u3002\u5bf9\u66f4\u5e7f\u6cdb\u7684 GLP-1 \u9886\u57df\u800c\u8a00\uff0c\u8fd9\u4e00\u4e8b\u4ef6\u5177\u6709\u652f\u6301\u610f\u4e49\uff1a\u5982\u679c\u5242\u91cf\u65b9\u6848\u6216\u5b89\u5168\u6027\u6743\u8861\u663e\u793a\u5dee\u5f02\u5316\uff0c\u5e02\u573a\u4ecd\u7136\u613f\u610f\u4e3a\u6311\u6218 Novo Nordisk \u548c Eli Lilly \u7684\u540e\u671f\u5019\u9009\u8005\u63d0\u4f9b\u8d44\u91d1\uff0c\u5373\u4fbf\u4ef7\u683c\u504f\u9ad8\u3002\u9884\u8ba1 Lilly \u548c Novo \u5c06\u4fdd\u6301\u7a33\u5b9a\uff1b\u4e24\u8005\u4ecd\u662f\u7597\u6548\u7684\u53c2\u7167\u6807\u51c6\u3002\u4f46\u4eca\u65e5\u5e02\u573a\u5956\u52b1\u4e86\u8fd9\u4e00\u679c\u65ad\u586b\u8865\u6218\u7565\u7a7a\u767d\u7684\u5927\u578b\u4e70\u5bb6\u3002<\/p>\n

\u4ea4\u6613\u6761\u6b3e\u4e0e\u91cc\u7a0b\u7891<\/h3>\n

\u57fa\u7840\u4ef7\u683c\u4e3a\u6bcf\u80a1 47.50 \u7f8e\u5143\u73b0\u91d1\u3002\u6bcf\u80a1\u6700\u9ad8 22.50 \u7f8e\u5143\u7684\u6216\u6709\u4ef7\u503c\u6743\uff08CVR\uff09\u53d6\u51b3\u4e8e Metsera \u8fbe\u6210\u82e5\u5e72\u65e2\u5b9a\u91cc\u7a0b\u7891\uff0c\u5305\u62ec\u9488\u5bf9\u4e3b\u5bfc\u7ec4\u5408\u65b9\u6848\u542f\u52a8\u4e09\u671f\u8bd5\u9a8c\u4ee5\u53ca\u5173\u952e\u5019\u9009\u836f\u7269\u6700\u7ec8\u83b7\u5f97 FDA \u6279\u51c6\u3002\u8be5\u7ed3\u6784\u5c06\u5927\u91cf\u98ce\u9669\u91cd\u65b0\u8f6c\u79fb\u7ed9\u5356\u65b9\uff0c\u540c\u65f6\u5141\u8bb8 Pfizer \u5728\u8d26\u9762\u4e0a\u5ba3\u79f0 49 \u4ebf\u7f8e\u5143\u7684\u4ef7\u683c\u6807\u7b7e\u3002\u8fd9\u662f\u751f\u7269\u5236\u836f\u4e2d\u5e38\u89c1\u7684\u6a21\u677f\uff1a\u5982\u679c\u7814\u53d1\u98ce\u9669\u4e0b\u964d\uff0c\u5934\u6761\u6570\u5b57\u8f83\u9ad8\uff1b\u5982\u679c\u4e0d\u964d\uff0c\u524d\u671f\u73b0\u91d1\u652f\u51fa\u8f83\u4f4e\u3002\u8be5\u7ed3\u6784\u4e5f\u8868\u660e\u5bf9\u8d44\u4ea7\u8fdb\u5c55\u7684\u4fe1\u5fc3\uff0c\u540c\u65f6\u5728 Pfizer \u8fd1\u671f\u6536\u8d2d\u6fc0\u589e\u540e\u5bf9\u8d44\u672c\u90e8\u7f72\u4fdd\u6301\u8c28\u614e\u3002\u4ea4\u6613\u5b8c\u6210\u5c06\u53d6\u51b3\u4e8e\u76d1\u7ba1\u6279\u51c6\u548c\u60ef\u5e38\u6761\u4ef6\u3002\u5982\u679c\u91cc\u7a0b\u7891\u8fbe\u6210\uff0cMetsera \u6301\u6709\u4eba\u6bcf\u80a1\u53ef\u80fd\u83b7\u5f97\u6700\u9ad8\u7ea6 70 \u7f8e\u5143\u7684\u5bf9\u4ef7\uff0c\u8fd9\u4e00\u6c34\u5e73\u6697\u793a Pfizer \u8ba4\u4e3a\u8fd9\u4e9b\u8d44\u4ea7\u80fd\u5728\u5176\u5185\u90e8\u9879\u76ee\u5931\u5229\u7684\u9886\u57df\u5c55\u5f00\u7ade\u4e89\u3002<\/p>\n

\u6218\u7565\u4e0e\u7ba1\u7ebf<\/h3>\n

\u8fd9\u662f\u4ece\u5185\u90e8\u521b\u65b0\u5411\u5916\u90e8\u521b\u65b0\u7684\u660e\u663e\u8f6c\u5411\u3002Pfizer \u7684\u53e3\u670d GLP-1 \u836f\u7269 danuglipron \u906d\u9047\u5b89\u5168\u963b\u529b\u5e76\u88ab\u505c\u4ea7\uff0c\u8fd9\u4ee4 Pfizer \u5728\u4e00\u4e2a\u8bb8\u591a\u4eba\u9884\u8ba1\u5230 2030 \u5e74\u4ee3\u521d\u5e74\u5e74\u9500\u552e\u989d\u5c06\u8d85\u8fc7 1000 \u4ebf\u7f8e\u5143\u7684\u7c7b\u522b\u4e2d\u7684\u8def\u5f84\u53d8\u5f97\u4e0d\u660e\u6717\u3002Metsera \u5e26\u6765\u4e86\u65e8\u5728\u89e3\u51b3\u9996\u6279 GLP-1 \u836f\u7269\u51fa\u73b0\u75db\u70b9\u7684\u8bd5\u9a8c\u6027\u51cf\u91cd\u7597\u6cd5\uff1a\u7ed9\u836f\u8d1f\u62c5\u3001\u4f9b\u5e94\u9650\u5236\u548c\u8010\u53d7\u6027\u3002\u5176\u4e2d\u4e00\u9879\u9879\u76ee\u662f\u957f\u6548\u6ce8\u5c04\u5242\uff0c\u5242\u91cf\u9891\u7387\u53ef\u80fd\u4f4e\u4e8e\u5f53\u524d\u4e3b\u6d41\u7684\u6bcf\u5468\u6ce8\u5c04\u3002\u8f83\u4f4e\u7684\u7ed9\u836f\u9891\u7387\u53ef\u6539\u5584\u4f9d\u4ece\u6027\u3001\u51cf\u5c11\u95e8\u8bca\u63a5\u89e6\u5e76\u51cf\u8f7b\u6bcf\u4f4d\u60a3\u8005\u7684\u5236\u9020\u538b\u529b\uff0c\u5f53\u4ea7\u80fd\u6210\u4e3a\u74f6\u9888\u65f6\uff0c\u8fd9\u662f\u4e00\u4e2a\u91cd\u8981\u4f18\u52bf\u3002Metsera \u8fd8\u5728\u63a8\u8fdb\u65e8\u5728\u653e\u5927\u51cf\u91cd\u6548\u679c\u540c\u65f6\u63a7\u5236\u80c3\u80a0\u9053\u526f\u4f5c\u7528\u7684\u7ec4\u5408\u7b56\u7565\uff0c\u8fd9\u662f\u65b0\u8fdb\u5165\u8005\u5728\u771f\u5b9e\u4e16\u754c\u4e2d\u9762\u4e34\u7684\u5173\u952e\u969c\u788d\u3002\u5982\u679c\u6570\u636e\u7ecf\u5f97\u8d77\u68c0\u9a8c\uff0cPfizer \u4e0d\u4ec5\u83b7\u5f97\u7ba1\u7ebf\uff0c\u8fd8\u83b7\u5f97\u4e00\u4e2a\u53ef\u6269\u5c55\u7684\u5dee\u5f02\u5316\u4ea7\u54c1\u7279\u5f81\u3002<\/p>\n

\u80a5\u80d6\u836f\u7269\u7ade\u8d5b<\/h3>\n

Novo Nordisk \u548c Eli Lilly \u901a\u8fc7 Wegovy\u3001Ozempic \u548c Zepbound \u5728\u7597\u6548\u548c\u5e02\u573a\u6267\u884c\u4e0a\u6811\u7acb\u4e86\u6807\u6746\u3002\u4ed6\u4eec\u5efa\u7acb\u4e86\u5f3a\u5927\u7684\u4f9b\u5e94\u94fe\u548c\u652f\u4ed8\u65b9\u8986\u76d6\uff0c\u5c3d\u7ba1\u8fd9\u4e9b\u4ecd\u5728\u5b8c\u5584\u4e2d\u3002\u5927\u578b\u5236\u836f\u4f01\u4e1a\u901a\u8fc7\u5e76\u8d2d\u4f5c\u51fa\u56de\u5e94\u3002Roche \u6536\u8d2d\u4e86 Carmot \u7684 GLP-1 \u7ec4\u5408\uff1bLilly \u6536\u8d2d\u4e86 Versanis \u4ee5\u589e\u5f3a\u4f53\u6210\u5206\u79d1\u5b66\uff1bAstraZeneca \u7b49\u516c\u53f8\u5219\u5f15\u8fdb\u4e86\u4e2d\u671f\u8d44\u4ea7\u3002Pfizer \u5728\u4e00\u6b21\u516c\u5f00\u7684\u632b\u6298\u540e\uff0c\u9009\u62e9\u8d2d\u4e70\u4e00\u4e2a\u53ef\u4fe1\u7684\u8d4c\u6ce8\uff0c\u800c\u4e0d\u662f\u4ece\u5934\u5f00\u59cb\u3002\u7ade\u4e89\u7b56\u7565\u5f88\u660e\u786e\uff1a\u5728\u7ed9\u836f\u9891\u7387\u3001\u526f\u4f5c\u7528\u8c31\u6216\u53e3\u670d\u9012\u9001\u4e0a\u5b9e\u73b0\u5dee\u5f02\u5316\uff0c\u7136\u540e\u6269\u5c55\u5236\u9020\u548c\u5e02\u573a\u51c6\u5165\u3002\u7ed9\u836f\u9891\u7387\u53ef\u80fd\u662f\u6700\u53ef\u884c\u7684\u5207\u5165\u70b9\u3002\u5982\u679c Metsera \u7684\u65b9\u6848\u5728\u6ce8\u5c04\u6b21\u6570\u8f83\u5c11\u7684\u60c5\u51b5\u4e0b\u5b9e\u73b0\u53ef\u6bd4\u7684\u51cf\u91cd\u6548\u679c\uff0c\u5b83\u53ef\u80fd\u5728\u7ef4\u6301\u6cbb\u7597\u4e2d\u83b7\u5f97\u5e02\u573a\u4efd\u989d\u2014\u2014\u5728\u8be5\u9886\u57df\u4fbf\u6377\u6027\u548c\u4f9d\u4ece\u6027\u5c24\u4e3a\u91cd\u8981\u2014\u2014\u5373\u4fbf\u6700\u9ad8\u7597\u6548\u4ecd\u7531\u73b0\u6709\u9886\u5148\u8005\u4fdd\u6301\u3002<\/p>\n

\u6574\u5408\u4e0e\u65f6\u95f4\u8868<\/h3>\n

\u73b0\u5728\u7684\u6267\u884c\u91cd\u70b9\u8f6c\u5411\u8bd5\u9a8c\u8bbe\u8ba1\u3001\u76d1\u7ba1\u6c9f\u901a\u548c\u5236\u9020\u89c4\u5212\u3002Pfizer \u7684\u7814\u53d1\u4e0e\u76d1\u7ba1\u57fa\u7840\u8bbe\u65bd\u662f\u5176\u4f18\u52bf\u3002\u5b83\u53ef\u4ee5\u52a0\u901f\u8bd5\u9a8c\u4e2d\u5fc3\u542f\u52a8\u3001\u6807\u51c6\u5316\u7ec8\u70b9\uff0c\u5e76\u4e3a\u5168\u7403\u89c4\u6a21\u7684\u4e09\u671f\u8bd5\u9a8c\u505a\u51c6\u5907\u3002\u5728\u5236\u9020\u65b9\u9762\uff0c\u957f\u6548\u5236\u5242\u901a\u5e38\u9700\u8981\u4e0d\u540c\u7684\u704c\u88c5-\u5b8c\u6210\u7b56\u7565\u548c\u4f9b\u5e94\u8ba1\u5212\u3002Pfizer \u5728\u75ab\u82d7\u548c\u80bf\u7624\u751f\u7269\u5236\u5242\u65b9\u9762\u62e5\u6709\u5145\u8db3\u7684\u4ea7\u80fd\u89c4\u5212\u7ecf\u9a8c\uff0c\u4f46 GLP-1 \u7684\u751f\u4ea7\u6709\u5176\u81ea\u8eab\u7ea6\u675f\uff1b\u65e9\u671f\u6295\u8d44\u4ee5\u907f\u514d Novo \u548c Lilly \u5728\u65e9\u671f\u51fa\u73b0\u7684\u74f6\u9888\u5c06\u81f3\u5173\u91cd\u8981\u3002\u5173\u952e\u89c2\u5bdf\u70b9\u662f\u4e3b\u5bfc\u9879\u76ee\u4e09\u671f\u8bd5\u9a8c\u7684\u542f\u52a8\u4ee5\u53ca\u5f53\u524d\u4e2d\u671f\u8bd5\u9a8c\u7684\u9876\u7ebf\u7ed3\u679c\uff0c\u8fd9\u4e9b\u7ed3\u679c\u5c06\u51b3\u5b9a\u76f8\u5bf9\u4e8e\u6bcf\u5468 GLP-1 \u6807\u51c6\u7684\u7ed9\u836f\u548c\u8010\u53d7\u6027\u3002CVR \u4e2d\u5d4c\u5165\u7684\u91cc\u7a0b\u7891\u5b9a\u4e49\u5e94\u4f5c\u4e3a\u8fd9\u4e9b\u50ac\u5316\u5242\u7684\u516c\u5f00\u8def\u7ebf\u56fe\uff0c\u4e3a\u6295\u8d44\u8005\u63d0\u4f9b\u63a8\u52a8\u4ef7\u503c\u8f6c\u79fb\u7684\u95e8\u69db\u53ef\u89c1\u6027\u3002<\/p>\n

\u4f30\u503c\u4e0e\u6295\u8d44\u8005\u89c2\u70b9<\/h3>\n

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