{"id":627989,"date":"2026-03-26T22:46:10","date_gmt":"2026-03-27T05:46:10","guid":{"rendered":"https:\/\/nai500.com\/?p=627989"},"modified":"2026-03-26T22:46:10","modified_gmt":"2026-03-27T05:46:10","slug":"%e8%bf%99%e4%b8%a4%e5%8f%aa%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80%e8%82%a1%e6%b3%a2%e5%8a%a8%e6%9e%81%e5%a4%a7%ef%bc%8c%e4%bd%86%e9%ab%98%e9%a3%8e%e9%99%a9%e8%83%8c%e5%90%8e%e4%b9%9f%e6%98%af%e9%ab%98","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2026\/03\/%e8%bf%99%e4%b8%a4%e5%8f%aa%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80%e8%82%a1%e6%b3%a2%e5%8a%a8%e6%9e%81%e5%a4%a7%ef%bc%8c%e4%bd%86%e9%ab%98%e9%a3%8e%e9%99%a9%e8%83%8c%e5%90%8e%e4%b9%9f%e6%98%af%e9%ab%98\/","title":{"rendered":"\u8fd9\u4e24\u53ea\u751f\u7269\u79d1\u6280\u80a1\u6ce2\u52a8\u6781\u5927\uff0c\u4f46\u9ad8\u98ce\u9669\u80cc\u540e\u4e5f\u662f\u9ad8\u56de\u62a5\u6f5c\u529b"},"content":{"rendered":"

\u5c3d\u7ba1\u5f53\u524d\u80a1\u5e02\u6ce2\u52a8\u52a0\u5267\uff0c\u4f46\u4ece\u5386\u53f2\u8868\u73b0\u6765\u770b\uff0c\u672a\u6765\u4e94\u5e74\u6743\u76ca\u8d44\u4ea7\u4ecd\u6709\u8f83\u5927\u6982\u7387\u5b9e\u73b0\u4e0d\u9519\u6536\u76ca\u3002\u5173\u952e\u5728\u4e8e\u9009\u5bf9\u6807\u7684\u3002\u672c\u6587\u805a\u7126\u4e24\u5bb6\u5728\u4e34\u5e8a\u9636\u6bb5\u8fdb\u5c55\u663e\u8457\uff0c\u4f46\u98ce\u9669\u540c\u6837\u9ad8\u4e8e\u5e73\u5747\u6c34\u5e73\u7684\u533b\u7597\u5065\u5eb7\u516c\u53f8\u2014\u2014Moderna\uff08MRNA\uff09<\/a><\/strong>\u4e0e\u00a0Abivax<\/strong>\uff08ABVX<\/strong>\uff09<\/strong><\/a>\u3002\u5b83\u4eec\u6216\u8bb8\u6b63\u662f\u98ce\u9669\u627f\u53d7\u80fd\u529b\u8f83\u5f3a\u7684\u6295\u8d44\u8005\u503c\u5f97\u5173\u6ce8\u7684\u201c\u4e94\u5e74\u4e4b\u7ea6\u201d\u9009\u9879\u3002<\/p>\n

1. Moderna\uff1amRNA\u5e73\u53f0\u84c4\u52bf\u5f85\u53d1<\/h2>\n

Moderna\u7684\u80a1\u4ef7\u4eca\u5e74\u5df2\u4e0a\u6da8\u7ea6 73%\uff0c\u6838\u5fc3\u9a71\u52a8\u529b\u6765\u81eamRNA\u6280\u672f\u5e73\u53f0\u7684\u6301\u7eed\u7a81\u7834\u3002\u4e0e\u4f20\u7edf\u75ab\u82d7\u76f8\u6bd4\uff0cmRNA\u75ab\u82d7\u5177\u5907\u751f\u4ea7\u901f\u5ea6\u5feb\u3001\u514d\u75ab\u5e94\u7b54\u66f4\u7cbe\u51c6\u7b49\u4f18\u52bf\u3002\u516c\u53f8\u5728\u65b0\u51a0\u75ab\u82d7\u4e4b\u5916\uff0c\u6b63\u52a0\u901f\u62d3\u5c55\u5176\u4ed6\u9002\u5e94\u75c7\uff1a<\/p>\n

    \n
  • \u6d41\u611f\u75ab\u82d7<\/strong>\uff1a\u5df2\u5728\u7f8e\u56fd\u9012\u4ea4\u4e0a\u5e02\u7533\u8bf7\uff0c\u76ee\u6807\u6539\u5584\u5f53\u524d40%-60%\u7684\u6709\u6548\u6027\u74f6\u9888\uff1b<\/li>\n
  • \u4e2a\u6027\u5316\u764c\u75c7\u75ab\u82d7mRNA-4157<\/strong>\uff1a\u4e0eMerck\u5408\u4f5c\uff0c\u6700\u65b0\u516c\u5e03\u7684 II \u671f\u4e94\u5e74\u968f\u8bbf\u6570\u636e\u663e\u793a\uff0c\u5728\u665a\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u4e2d\uff0cmRNA-4157\u8054\u5408Keytruda\u663e\u8457\u964d\u4f4e\u590d\u53d1\u6216\u6b7b\u4ea1\u98ce\u9669\u3002\u8be5\u5019\u9009\u836f\u7269\u76ee\u524d\u5df2\u5728\u591a\u79cd\u764c\u75c7\u7c7b\u578b\u4e2d\u63a8\u8fdb\u81f3 II\/III \u671f\u7814\u7a76\u3002<\/li>\n<\/ul>\n

    \u98ce\u9669\u63d0\u793a<\/strong>\uff1aModerna \u7684\u6838\u5fc3\u5728\u4e8e\u4e34\u5e8a\u4e0e\u76d1\u7ba1\u8fdb\u5c55\u3002\u4efb\u4f55\u5173\u952e\u5019\u9009\u836f\u7269\u7684\u8bd5\u9a8c\u5931\u8d25\u6216\u5ba1\u6279\u5ef6\u8fdf\u90fd\u53ef\u80fd\u5f15\u53d1\u80a1\u4ef7\u5267\u70c8\u6ce2\u52a8\u3002\u5bf9\u4e8e\u8ffd\u6c42\u7a33\u5065\u7684\u6295\u8d44\u8005\u800c\u8a00\uff0c\u8fd9\u7c7b\u4e0d\u786e\u5b9a\u6027\u9700\u8981\u63d0\u524d\u7eb3\u5165\u8003\u91cf\u3002<\/p>\n

    2. Abivax\uff1a\u6311\u6218\u767e\u4ebf\u708e\u75c7\u6027\u80a0\u75c5\u5e02\u573a<\/h2>\n

    \u603b\u90e8\u4f4d\u4e8e\u6cd5\u56fd\u7684\u751f\u7269\u79d1\u6280\u516c\u53f8Abivax\u6b63\u8bd5\u56fe\u5728\u7ade\u4e89\u6fc0\u70c8\u7684\u6e83\u75a1\u6027\u7ed3\u80a0\u708e\uff08UC\uff09\u836f\u7269\u5e02\u573a\u4e2d\u7a81\u56f4\u3002\u6838\u5fc3\u5019\u9009\u836f\u7269\u00a0obefazimod<\/strong>\u00a0\u7684\u5dee\u5f02\u5316\u4eae\u70b9\u5728\u4e8e\uff1a\u4e0d\u4f9d\u8d56\u4f20\u7edf\u514d\u75ab\u6291\u5236\u673a\u5236\uff0c\u6709\u671b\u5728\u4fdd\u8bc1\u7597\u6548\u7684\u540c\u65f6\uff0c\u89c4\u907fJAK\u6291\u5236\u5242\u7c7b\u836f\u7269\u5728\u5fc3\u8840\u7ba1\u5b89\u5168\u7b49\u65b9\u9762\u7684\u9ed1\u6846\u8b66\u544a\u98ce\u9669\u3002<\/p>\n

    \u5728III\u671f\u7814\u7a76\u4e2d\uff0cobefazimod\u8fbe\u5230\u4e34\u5e8a\u7f13\u89e3\u7684\u4e3b\u8981\u7ec8\u70b9\uff0c\u4e14\u5165\u7ec4\u60a3\u8005\u4e2d\u7ea647.3%\u66fe\u63a5\u53d7\u8fc7\u5176\u4ed6\u6cbb\u7597\uff08\u5305\u62ecJAK\u6291\u5236\u5242\uff09\u5931\u8d25\u3002\u82e5\u6700\u7ec8\u83b7\u6279\uff0c\u8be5\u836f\u7269\u6709\u671b\u6311\u6218\u5f53\u524d\u5e74\u9500\u552e\u989d\u6570\u5341\u4ebf\u7f8e\u5143\u7684\u6210\u719f\u4ea7\u54c1\u7ebf\u3002<\/p>\n

    \u5173\u952e\u50ac\u5316\u5242<\/strong>\uff1a\u516c\u53f8\u9884\u8ba1\u4e8e\u4eca\u5e74\u4e8c\u5b63\u5ea6\u516c\u5e03\u4e00\u9879UC\u60a3\u8005\u7ef4\u6301\u6cbb\u7597\u7814\u7a76\u7684\u6570\u636e\u3002\u82e5\u7ed3\u679c\u79ef\u6781\uff0c\u53ef\u80fd\u6210\u4e3a\u80a1\u4ef7\u91cd\u8981\u7684\u50ac\u5316\u56e0\u7d20\u3002<\/p>\n

    \u98ce\u9669\u63d0\u793a<\/strong>\uff1aAbivax\u76ee\u524d\u5c1a\u65e0\u5546\u4e1a\u5316\u4ea7\u54c1\uff0c\u6240\u6709\u4ef7\u503c\u9ad8\u5ea6\u96c6\u4e2d\u4e8eobefazimod\u7684\u4e34\u5e8a\u4e0e\u76d1\u7ba1\u6210\u8d25\u3002\u4e00\u65e6\u6570\u636e\u4e0d\u53ca\u9884\u671f\uff0c\u80a1\u4ef7\u6ce2\u52a8\u5c06\u6781\u4e3a\u5267\u70c8\u3002<\/p>\n

    \u5c0f\u7ed3<\/h2>\n

    Moderna\u4e0eAbivax\u5747\u5904\u4e8e\u4e34\u5e8a\u63a8\u8fdb\u7684\u5173\u952e\u9636\u6bb5\uff0c\u5404\u81ea\u5728mRNA\u6280\u672f\u4e0e\u514d\u75ab\u8c03\u8282\u9886\u57df\u5177\u5907\u5dee\u5f02\u5316\u4f18\u52bf\u3002\u82e5\u4e34\u5e8a\u8fdb\u5c55\u987a\u5229\uff0c\u672a\u6765\u4e94\u5e74\u6709\u671b\u5b9e\u73b0\u663e\u8457\u8d85\u8d8a\u5927\u76d8\u7684\u8868\u73b0\uff1b\u53cd\u4e4b\uff0c\u4e5f\u9762\u4e34\u8fdc\u9ad8\u4e8e\u5e73\u5747\u6c34\u5e73\u7684\u56de\u64a4\u98ce\u9669\u3002\u5bf9\u4e8e\u80fd\u591f\u627f\u53d7\u8f83\u9ad8\u6ce2\u52a8\u4e14\u613f\u610f\u4ee5\u65f6\u95f4\u6362\u7a7a\u95f4\u7684\u6295\u8d44\u8005\u800c\u8a00\uff0c\u8fd9\u4e24\u53ea\u751f\u7269\u79d1\u6280\u80a1\u503c\u5f97\u7eb3\u5165\u89c2\u5bdf\u6e05\u5355\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

    \u5c3d\u7ba1\u5f53\u524d\u80a1\u5e02\u6ce2\u52a8\u52a0\u5267\uff0c\u4f46\u4ece\u5386\u53f2\u8868\u73b0\u6765\u770b\uff0c\u672a\u6765\u4e94\u5e74\u6743\u76ca\u8d44\u4ea7\u4ecd\u6709\u8f83\u5927\u6982\u7387\u5b9e\u73b0\u4e0d\u9519\u6536\u76ca\u3002\u5173\u952e\u5728\u4e8e\u9009\u5bf9\u6807\u7684\u3002\u672c\u6587\u805a\u7126\u4e24 […]<\/p>\n","protected":false},"author":27,"featured_media":488766,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1521,430],"tags":[455,747,925,459],"class_list":["post-627989","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1521","category-trends-strategies-zh-hans","tag-455","tag-747","tag-925","tag-459","sectors-life-science-zh-hans","locations-us-zh-hans","exchange-nasdaq-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/627989","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=627989"}],"version-history":[{"count":3,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/627989\/revisions"}],"predecessor-version":[{"id":627992,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/posts\/627989\/revisions\/627992"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media\/488766"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=627989"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=627989"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=627989"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}