{"id":631911,"date":"2026-04-16T23:19:13","date_gmt":"2026-04-17T06:19:13","guid":{"rendered":"https:\/\/nai500.com\/?p=631911"},"modified":"2026-04-16T23:19:13","modified_gmt":"2026-04-17T06:19:13","slug":"%e4%bd%8e%e8%b0%83%e5%8d%b4%e6%9c%89%e5%ae%9e%e5%8a%9b%e4%b8%89%e5%8f%aa%e8%a2%ab%e5%bf%bd%e8%a7%86%e7%9a%84%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80%e8%82%a1%e5%80%bc%e5%be%97%e5%85%b3%e6%b3%a8","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hans\/blog\/2026\/04\/%e4%bd%8e%e8%b0%83%e5%8d%b4%e6%9c%89%e5%ae%9e%e5%8a%9b%e4%b8%89%e5%8f%aa%e8%a2%ab%e5%bf%bd%e8%a7%86%e7%9a%84%e7%94%9f%e7%89%a9%e7%a7%91%e6%8a%80%e8%82%a1%e5%80%bc%e5%be%97%e5%85%b3%e6%b3%a8\/","title":{"rendered":"\u4f4e\u8c03\u5374\u6709\u5b9e\u529b\uff0c\u4e09\u53ea\u88ab\u5ffd\u89c6\u7684\u751f\u7269\u79d1\u6280\u80a1\u503c\u5f97\u5173\u6ce8"},"content":{"rendered":"<p class=\"p1\"><span class=\"s1\">\u5728\u533b\u7597\u5065\u5eb7\u677f\u5757\uff0c\u793c\u6765\u3001\u5f3a\u751f\u3001\u8054\u5408\u5065\u5eb7\u7b49\u5de8\u5934\u5f80\u5f80\u5438\u5f15\u4e86\u5927\u90e8\u5206\u6295\u8d44\u8005\u7684\u76ee\u5149\u3002\u7136\u800c\uff0c\u5728\u8fd9\u4e9b\u5de8\u5934\u4e4b\u5916\uff0c\u8fd8\u6709\u4e0d\u5c11\u77e5\u540d\u5ea6\u8f83\u4f4e\u4f46\u540c\u6837\u503c\u5f97\u8ba4\u771f\u5173\u6ce8\u7684\u533b\u7597\u4fdd\u5065\u80a1\u7968\u3002\u4ee5\u4e0b\u4e09\u53ea\u751f\u7269\u79d1\u6280\u80a1\u2014\u2014Krystal Biotech\uff08<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=krys\"><span class=\"s2\">KRYS<\/span><\/a>\uff09\u3001Madrigal Pharmaceuticals\uff08<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=mdgl\"><span class=\"s2\">MDGL<\/span><\/a>\uff09\u548cExelixis\uff08<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=exel\"><span class=\"s2\">EXEL<\/span><\/a>\uff09\u2014\u2014\u5c3d\u7ba1\u5e76\u975e\u884c\u4e1a\u4e3b\u6d41\u73a9\u5bb6\uff0c\u4f46\u503c\u5f97\u52a0\u5165\u60a8\u7684\u89c2\u5bdf\u540d\u5355\u3002<\/span><\/p>\n<h2 class=\"p1\"><span class=\"s1\">Krystal Biotech<\/span><\/h2>\n<p class=\"p1\"><span class=\"s1\">Krystal 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Pharmaceuticals\u57282024\u5e74\u4e5f\u53d6\u5f97\u4e86\u91cd\u5927\u7a81\u7834\uff0c\u5176\u7814\u53d1\u7684Rezdiffra\u83b7\u5f97FDA\u6279\u51c6\uff0c\u6210\u4e3a\u9996\u4e2a\u7528\u4e8e\u6cbb\u7597\u4ee3\u8c22\u529f\u80fd\u969c\u788d\u76f8\u5173\u8102\u80aa\u6027\u809d\u708e\uff08MASH\uff09\u7684\u836f\u7269\u3002Rezdiffra\u76ee\u524d\u83b7\u5f97\u7684\u662f\u52a0\u901f\u6279\u51c6\uff0c\u610f\u5473\u7740\u6b63\u5728\u8fdb\u884c\u7684\u786e\u8bc1\u6027\u4e34\u5e8a\u8bd5\u9a8c\u5c06\u8bc4\u4f30\u5176\u7597\u6548\uff1b\u5982\u679c\u8bd5\u9a8c\u5931\u8d25\uff0c\u8be5\u836f\u53ef\u80fd\u88ab\u64a4\u5e02\u3002<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">\u7136\u800c\uff0c\u8fd9\u5e76\u672a\u963b\u6b62\u533b\u751f\u5f00\u5177Rezdiffra\u5904\u65b9\u30022025\u5e74\uff0cMadrigal 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Pharmaceuticals\u8fd8\u6709\u591a\u4e2a\u4e13\u6ce8\u4e8eMASH\u7684\u7814\u53d1\u7ba1\u7ebf\u5019\u9009\u836f\u7269\uff0c\u6709\u671b\u5e2e\u52a9\u5176\u6269\u5927\u53ef\u53ca\u5e02\u573a\u3002\u968f\u7740\u8be5\u516c\u53f8\u5728\u8fd9\u4e00\u7ec6\u5206\u9886\u57df\u83b7\u5f97\u5e02\u573a\u4efd\u989d\uff0c\u5176\u80a1\u7968\u6709\u671b\u5e26\u6765\u51fa\u8272\u56de\u62a5\u3002<\/span><\/p>\n<h2 class=\"p1\"><span class=\"s1\">Exelixis<\/span><\/h2>\n<p class=\"p1\"><span class=\"s1\">Exelixis\u662f\u4e00\u5bb6\u80bf\u7624\u5b66\u4e13\u4e1a\u516c\u53f8\u3002\u5176\u6700\u91cd\u8981\u7684\u836f\u7269Cabometyx\u7528\u4e8e\u6cbb\u7597\u67d0\u4e9b\u7c7b\u578b\u7684\u809d\u764c\u548c\u80be\u764c\u3002Cabometyx\u5df2\u83b7\u5f97\u591a\u9879\u9002\u5e94\u75c7\u6279\u51c6\uff0c\u5305\u62ec\u4f5c\u4e3a\u8054\u5408\u6cbb\u7597\u65b9\u6848\uff0c\u540c\u65f6\u5b83\u4ecd\u7136\u662f\u80be\u7ec6\u80de\u764c\u9886\u57df\u540c\u7c7b\u836f\u7269\u4e2d\u5904\u65b9\u91cf\u6700\u5927\u7684\u836f\u7269\u3002\u591a\u5e74\u6765\uff0cCabometyx\u4e00\u76f4\u662fExelixis\u7684\u4e3b\u8981\u589e\u957f\u52a8\u529b\uff0c\u8fd9\u4e00\u5730\u4f4d\u9884\u8ba1\u5c06\u6301\u7eed\u52302030\u5e74\u521d\u8be5\u836f\u9762\u4e34\u4eff\u5236\u836f\u7ade\u4e89\u4e4b\u524d\u3002<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">\u5230\u90a3\u65f6\uff0cExelixis\u7684\u5df2\u83b7\u6279\u836f\u7269\u4ea7\u54c1\u7ebf\u5e94\u4f1a\u53d1\u751f\u6539\u53d8\u3002\u8be5\u516c\u53f8\u6b63\u5728\u5f00\u53d1\u591a\u79cd\u4e0b\u4e00\u4ee3\u764c\u75c7\u7597\u6cd5\uff0c\u5176\u4e2d\u4e00\u79cd\u540d\u4e3azanzalintinib\u7684\u836f\u7269\u6b63\u88ab\u8003\u8651\u6279\u51c6\u4f5c\u4e3a\u7ed3\u76f4\u80a0\u764c\uff08CRC\uff09\u7684\u8054\u5408\u6cbb\u7597\u65b9\u6848\u3002\u7ed3\u76f4\u80a0\u764c\u662f\u5168\u7403\u764c\u75c7\u6b7b\u4ea1\u7684\u7b2c\u4e8c\u5927\u539f\u56e0\uff0c\u8fd9\u4e00\u9886\u57df\u5b58\u5728\u5de8\u5927\u7684\u672a\u6ee1\u8db3\u533b\u7597\u9700\u6c42\u3002<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">Exelixis\u8fd8\u6709\u591a\u4e2a\u7814\u53d1\u7ba1\u7ebf\u5019\u9009\u836f\u7269\uff0c\u9884\u8ba1\u672a\u6765\u4e94\u5e74\u5185\u5c06\u53d6\u5f97\u8fdb\u5c55\u3002\u8be5\u516c\u53f8\u5df2\u88ab\u8bc1\u660e\u662f\u80bf\u7624\u5b66\u9886\u57df\u7684\u521b\u65b0\u8005\uff0c\u800c\u8fd9\u4e00\u7ec6\u5206\u9886\u57df\u901a\u5e38\u7531\u5927\u578b\u5236\u836f\u4f01\u4e1a\u4e3b\u5bfc\u3002\u8fd9\u4e00\u70b9\uff0c\u52a0\u4e0aExelixis\u5f3a\u52b2\u7684\u8d22\u52a1\u4e1a\u7ee9\uff0c\u4f7f\u5176\u80a1\u7968\u503c\u5f97\u8ba4\u771f\u8003\u8651\u3002<\/span><\/p>\n<h2 class=\"p1\"><span class=\"s1\">\u603b\u7ed3<\/span><\/h2>\n<p class=\"p1\"><span class=\"s1\">\u603b\u4f53\u800c\u8a00\uff0cKrystal Biotech\u3001Madrigal Pharmaceuticals\u548cExelixis\u8fd9\u4e09\u5bb6\u516c\u53f8\u867d\u4e0d\u5c5e\u533b\u7597\u5065\u5eb7\u677f\u5757\u7684\u5de8\u5934\uff0c\u4f46\u5404\u81ea\u5728\u7f55\u89c1\u75c5\u3001\u4ee3\u8c22\u529f\u80fd\u969c\u788d\u76f8\u5173\u8102\u80aa\u6027\u809d\u708e\u548c\u80bf\u7624\u5b66\u9886\u57df\u53d6\u5f97\u4e86\u5173\u952e\u6027\u7684\u836f\u7269\u83b7\u6279\u7a81\u7834\uff0c\u5e76\u62e5\u6709\u660e\u786e\u7684\u589e\u957f\u8def\u5f84\u548c\u540e\u7eed\u7814\u53d1\u7ba1\u7ebf\u3002\u5bf9\u4e8e\u5173\u6ce8\u751f\u7269\u79d1\u6280\u7ec6\u5206\u9886\u57df\u6295\u8d44\u673a\u4f1a\u7684\u6295\u8d44\u8005\u800c\u8a00\uff0c\u8fd9\u4e09\u53ea\u80a1\u7968\u63d0\u4f9b\u4e86\u4e0d\u540c\u4e8e\u884c\u4e1a\u5de8\u5934\u7684\u5dee\u5f02\u5316\u9009\u62e9\u3002<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5728\u533b\u7597\u5065\u5eb7\u677f\u5757\uff0c\u793c\u6765\u3001\u5f3a\u751f\u3001\u8054\u5408\u5065\u5eb7\u7b49\u5de8\u5934\u5f80\u5f80\u5438\u5f15\u4e86\u5927\u90e8\u5206\u6295\u8d44\u8005\u7684\u76ee\u5149\u3002\u7136\u800c\uff0c\u5728\u8fd9\u4e9b\u5de8\u5934\u4e4b\u5916\uff0c\u8fd8\u6709\u4e0d\u5c11\u77e5\u540d\u5ea6\u8f83 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