{"id":237391,"date":"2018-08-29T20:01:54","date_gmt":"2018-08-30T03:01:54","guid":{"rendered":"https:\/\/nai500.com\/?p=237391"},"modified":"2018-08-29T20:01:54","modified_gmt":"2018-08-30T03:01:54","slug":"%e4%b8%ad%e5%9c%8b%e7%a7%91%e5%ad%b8%e5%ae%b6%e5%88%a9%e7%94%a8trialtus-bioscience%e7%9a%84cl-7%e7%b4%94%e5%8c%96%e7%b3%bb%e7%b5%b1%e7%b4%94%e5%8c%96crispr%e7%9b%b8%e9%97%9c%e8%9b%8b%e7%99%bdcas9","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2018\/08\/%e4%b8%ad%e5%9c%8b%e7%a7%91%e5%ad%b8%e5%ae%b6%e5%88%a9%e7%94%a8trialtus-bioscience%e7%9a%84cl-7%e7%b4%94%e5%8c%96%e7%b3%bb%e7%b5%b1%e7%b4%94%e5%8c%96crispr%e7%9b%b8%e9%97%9c%e8%9b%8b%e7%99%bdcas9\/","title":{"rendered":"\u4e2d\u570b\u79d1\u5b78\u5bb6\u5229\u7528TriAltus Bioscience\u7684CL-7\u7d14\u5316\u7cfb\u7d71\u7d14\u5316CRISPR\u76f8\u95dc\u86cb\u767dCas9\u548cCas12a"},"content":{"rendered":"<p>TriAltus Bioscience, LLC\u4eca\u5929\u5ba3\u5e03\uff0c\u4e2d\u570b\u6e56\u5317\u5927\u5b78\u7684\u79d1\u5b78\u5bb6\u5229\u7528TriAltus Bioscience\u7372\u5f97\u8a31\u53ef\u7684CL-7\u51c8\u5316\u6280\u8853\uff0c\u6210\u529f\u5171\u8868\u9054\u4e26\u7d14\u5316\u4e86\u5927\u8178\u687f\u83cc\u4e2d\u7684\u5305\u62ecCRISPR\u76f8\u95dc\u86cb\u767dCas9\u548cCas12a\u5728\u5167\u7684\u6838\u7cd6\u6838\u86cb\u767d\u5fa9\u5408\u7269\u3002\u6e56\u5317\u5927\u5b78\u7684\u79d1\u5b78\u5bb6\u57287\u6708\u5e95\u516c\u5e03\u4e86\u4ed6\u5011\u7684\u5de5\u4f5c\u6210\u679c\u3002<\/p>\n<p>TriAltus Bioscience\u516c\u53f8\u9996\u5e2d\u57f7\u884c\u5b98\u517c\u806f\u5408\u5275\u59cb\u4ebaBob Shufflebarger\u8aaa\uff1a\u201c\u9019\u500b\u5718\u968a\u5728CRISPR\u86cb\u767d\u8cea\u7d14\u5316\u65b9\u9762\u53d6\u5f97\u4e86\u6210\u529f\uff0c\u7368\u7acb\u9a57\u8b49\u4e86\u6211\u5011\u7684CL-7\u7d14\u5316\u7cfb\u7d71\u53ef\u4ee5\u6709\u6548\u5730\u7d14\u5316\u4e00\u4e9b\u7528\u65bc\u6cbb\u7642\u7814\u7a76\u7684\u6700\u91cd\u8981\u7684\u86cb\u767d\u8cea\u3002\u6211\u5011\u76f8\u4fe1\u9019\u9805\u6280\u8853\u5c07\u52a0\u5f37\u79d1\u5b78\u7814\u7a76\uff0c\u89e3\u6c7a\u8207\u57fa\u56e0\u5de5\u7a0b\u86cb\u767d\u8cea\u5408\u4f5c\u7684\u4e00\u4e9b\u6311\u6230\uff0c\u4e26\u6700\u7d42\u6709\u52a9\u65bc\u964d\u4f4e\u8207\u751f\u7269\u5236\u85e5\u751f\u7522\u76f8\u95dc\u7684\u884c\u696d\u6210\u672c\u3002\u201d<\/p>\n<p>\u6e56\u5317\u5927\u5b78\u7684\u79d1\u5b78\u5bb6\u5728\u4ed6\u5011\u7684\u8ad6\u6587\u4e2d\u5beb\u9053\uff1a\u201c\u901a\u904e\u5229\u7528\u8d85\u9ad8\u89aa\u548c\u529b\u7684CL7 \/ Im7\u7d14\u5316\u7cfb\u7d71\uff0c\u6211\u5011\u5728\u9ad4\u5916\u548c\u9ad4\u5167\u5b8c\u6210\u4e86\u6838\u9178\u9176\u6d3b\u6027\u7d14Cas RNP\u7684\u4e00\u6b65\u7d14\u5316\uff0c\u8868\u660e\u8a72\u7d14\u5316\u65b9\u6cd5\u5177\u6709\u5f88\u597d\u7684\u6548\u679c\uff0c\u6709\u5927\u898f\u6a21\u3001\u4f4e\u6210\u672c\u548c\u77ed\u6642\u9593\u5236\u5099CRISPR\u76f8\u95dc\u6838\u9178\u9176\u7684\u6f5b\u529b\u3002 \u201d<\/p>\n<p>CRISPR\u662f\u4e00\u7a2e\u57fa\u56e0\u7de8\u8f2f\u5de5\u5177\uff0c\u53ef\u6709\u6548\u5730\u4e26\u4e14\u7279\u7570\u6027\u5730\u6539\u8b8a\u751f\u7269\u9ad4\u5167\u7684\u57fa\u56e0\u3002\u8207CRISPR\u76f8\u95dc\u7684\u86cb\u767d\u5982Cas9\u548cCas12a\u662fCRISPR\u7cfb\u7d71\u7684\u5fc5\u9700\u7d44\u5206\u3002\u7814\u7a76\u4eba\u54e1\u8d8a\u4f86\u8d8a\u591a\u5730\u4f7f\u7528CRISPR\u4f86\u5c0b\u627e\u6cbb\u7642\u764c\u7665\u3001\u827e\u6ecb\u548c\u942e\u72c0\u7d30\u80de\u75c5\u7b49\u75be\u75c5\u7684\u6f5b\u5728\u6cbb\u7642\u65b9\u6cd5\u3002<\/p>\n<p>\u82f1\u6587\u4f86\u6e90\uff1aBiospace<\/p>\n","protected":false},"excerpt":{"rendered":"<p>TriAltus Bioscience, LLC\u4eca\u5929\u5ba3\u5e03\uff0c\u4e2d\u570b\u6e56\u5317\u5927\u5b78\u7684\u79d1\u5b78\u5bb6\u5229\u7528TriAltus Biosc [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":237380,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[426],"tags":[809,927,563,644,570,564],"class_list":["post-237391","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hant","tag-809","tag-927","tag--zh-hant","tag-644","tag-570","tag-564","sectors-life-science-zh-hant","locations-china-zh-hant","locations-us-zh-hant","exchange-608"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/237391","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=237391"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/237391\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/237380"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=237391"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=237391"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=237391"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}