{"id":241911,"date":"2018-10-11T23:43:15","date_gmt":"2018-10-12T06:43:15","guid":{"rendered":"https:\/\/nai500.com\/?p=241911"},"modified":"2018-10-11T23:43:15","modified_gmt":"2018-10-12T06:43:15","slug":"%e7%be%85%e6%b0%8f%e8%88%87ionis%e9%81%94%e6%88%90%e5%83%b9%e5%80%bc%e8%b6%85%e9%81%8e7%e5%84%84%e7%be%8e%e5%85%83%e6%96%b0%e5%90%88%e4%bd%9c%ef%bc%8c%e5%b1%95%e9%96%8b%e5%b9%b9%e6%80%a7amd%e6%b2%bb","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2018\/10\/%e7%be%85%e6%b0%8f%e8%88%87ionis%e9%81%94%e6%88%90%e5%83%b9%e5%80%bc%e8%b6%85%e9%81%8e7%e5%84%84%e7%be%8e%e5%85%83%e6%96%b0%e5%90%88%e4%bd%9c%ef%bc%8c%e5%b1%95%e9%96%8b%e5%b9%b9%e6%80%a7amd%e6%b2%bb\/","title":{"rendered":"\u7f85\u6c0f\u8207Ionis\u9054\u6210\u50f9\u503c\u8d85\u904e7\u5104\u7f8e\u5143\u65b0\u5408\u4f5c\uff0c\u5c55\u958b\u5e79\u6027AMD\u6cbb\u7642"},"content":{"rendered":"

Ionis Pharmaceuticals\u5ba3\u5e03\u8207\u7f85\u6c0f\uff08Roche\uff09\u9054\u6210\u4e00\u9805\u5408\u4f5c\uff0c\u5171\u540c\u958b\u767cIONIS-FB-LRx\uff0c\u7528\u65bc\u6cbb\u7642\u88dc\u9ad4\u4ecb\u5c0e\u7684\u75be\u75c5\u3002\u6b64\u6b21\u5408\u4f5c\u5c07\u5229\u7528Ionis\u5728RNA\u9776\u5411\u6cbb\u7642\u65b9\u9762\u7684\u9818\u5c0e\u5730\u4f4d\uff0c\u958b\u767c\u91dd\u5c0d\u56e0\u5b50B\uff08factor B, FB\uff09\u7684IONIS-FB-LRx\u7642\u6cd5\uff0c\u6cbb\u7642\u591a\u7a2e\u9069\u61c9\u7665\u3002<\/p>\n

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AMD\u662f\u5c0e\u81f4\u8001\u5e74\u4eba\u5931\u660e\u7684\u6700\u5e38\u898b\u539f\u56e0\u3002AMD\u7684\u665a\u671f\u968e\u6bb5\u88ab\u5206\u70ba\u201c\u6fd5\u6027\u201d\u6216\u201c\u5e79\u6027\u201d\uff0c\u7d0490\uff05\u7684\u7f8e\u570b\u75c5\u4f8b\u88ab\u8a3a\u65b7\u70ba\u201c\u5e79\u6027\u201d\u3002\u5e79\u6027AMD\u662f\u5c0e\u81f4\u7f8e\u570b\u548c\u767c\u9054\u570b\u5bb6\u8001\u5e74\u4eba\u5931\u660e\u7684\u4e3b\u8981\u539f\u56e0\u3002\u52302020\u5e74\uff0c\u9019\u7a2e\u75be\u75c5\u9810\u8a08\u5c07\u5f71\u97ff\u4e16\u754c\u4e0a1.96\u5104\u4eba\u7684\u751f\u6d3b\u3002GA\u662f\u5e79\u6027AMD\u7684\u665a\u671f\u8868\u73fe\uff0c\u662f\u8996\u7db2\u819c\u8272\u7d20\u4e0a\u76ae\uff08RPE\uff09\u7d30\u80de\u3001\u611f\u5149\u7d30\u80de\u548c\u8996\u7db2\u819c\u4e2d\u592e\u7684\u8108\u7d61\u819c\u6bdb\u7d30\u8840\u7ba1\u7684\u9010\u6f38\u55aa\u5931\u5c0e\u81f4\u7684\u3002\u7f79\u60a3GA\u7684\u60a3\u8005\u96e3\u4ee5\u8b58\u5225\u9762\u90e8\u3001\u95b1\u8b80\u901f\u5ea6\u964d\u4f4e\u3001\u96e3\u4ee5\u5728\u591c\u9593\u9032\u884c\u99d5\u99db\uff0c\u751a\u81f3\u6700\u7d42\u6703\u5931\u660e\u3002\u64da\u4f30\u8a08\uff0c\u5168\u7403\u6709\u8d85\u904e500\u842c\u4eba\u60a3\u6709GA\uff0c\u7136\u800c\u8a72\u75c5\u76ee\u524d\u9084\u6c92\u6709\u7372\u6279\u7684\u6cbb\u7642\u65b9\u6cd5\u3002<\/p>\n

Ionis\u5229\u7528\u5176\u5148\u9032\u7684\u914d\u9ad4\u5171\u8edb\u53cd\u7fa9\uff08LICA\uff09\u6280\u8853\u7814\u767c\u7684\u53cd\u7fa9\u85e5\u7269IONIS-FB-LRx\u53ef\u4ee5\u6e1b\u5c11\u88dc\u9ad4\u5148\u5929\u514d\u75ab\u7cfb\u7d71\u4e2d\u95dc\u9375\u86cb\u767dFB\u7684\u7522\u751f\uff0c\u6709\u671b\u70ba\u9019\u985e\u60a3\u8005\u5e36\u4f86\u798f\u97f3\u3002\u572854\u540d\u5065\u5eb7\u8a8c\u9858\u8005\u76841\u671f\u7814\u7a76\u4e2d\uff0cIONIS-FB-L\u964d\u4f4e\u4e86\u8840\u6f3fFB\uff0c\u5b89\u5168\u4e14\u8010\u53d7\u6027\u826f\u597d\u3002<\/p>\n

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