{"id":258545,"date":"2019-03-12T16:32:52","date_gmt":"2019-03-12T23:32:52","guid":{"rendered":"https:\/\/nai500.com\/?p=258545"},"modified":"2019-03-12T16:32:52","modified_gmt":"2019-03-12T23:32:52","slug":"%e4%b8%ad%e5%9c%8b%e7%a7%91%e6%bf%9f%e7%94%9f%e7%89%a9%e7%8d%b2bcma-car-t%e7%b4%b0%e8%83%9e%e6%b2%bb%e7%99%82%e8%87%a8%e5%ba%8a%e8%a9%a6%e9%a9%97%e8%a8%b1%e5%8f%af","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2019\/03\/%e4%b8%ad%e5%9c%8b%e7%a7%91%e6%bf%9f%e7%94%9f%e7%89%a9%e7%8d%b2bcma-car-t%e7%b4%b0%e8%83%9e%e6%b2%bb%e7%99%82%e8%87%a8%e5%ba%8a%e8%a9%a6%e9%a9%97%e8%a8%b1%e5%8f%af\/","title":{"rendered":"\u4e2d\u570b\u79d1\u6fdf\u751f\u7269\u7372BCMA-CAR-T\u7d30\u80de\u6cbb\u7642\u81e8\u5e8a\u8a66\u9a57\u8a31\u53ef"},"content":{"rendered":"<p>\u79d1\u6fdf\u751f\u7269\u91ab\u85e5\uff08\u4e0a\u6d77\uff09\u6709\u9650\u516c\u53f8\uff08\u79d1\u6fdf\u751f\u7269\uff0cCARsgen Therapeutics\uff09\u662f\u4e00\u5bb6\u81f4\u529b\u65bc\u958b\u767c\u764c\u7665\u5d4c\u5408\u6297\u539f\u53d7\u9ad4T\u7d30\u80de\u7642\u6cd5\u7684\u81e8\u5e8a\u968e\u6bb5\u516c\u53f8\uff0c\u4eca\u5929\u5ba3\u5e03\u5176\u4e3b\u8981\u5019\u9078\u85e5\u7269CT053 \u5168\u4eba\u6297 BCMA \u81ea\u9ad4 CAR T \u7d30\u80de\u8a3b\u5c04\u6db2\u7528\u65bc\u6cbb\u7642\u5fa9\u767c\u96e3\u6cbb\u591a\u767c\u6027\u9aa8\u9ad3\u7624\u7684\u81e8\u5e8a\u8a66\u9a57\u7533\u8acb\u5df2\u901a\u904e\u4e86\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u81e8\u5e8a\u8a66\u9a57\u8a31\u53ef\u3002<\/p>\n<p>\u79d1\u6fdf\u751f\u7269\u8463\u4e8b\u9577\u3001\u9996\u5e2d\u57f7\u884c\u5b98\u517c\u9996\u5e2d\u79d1\u5b78\u5b98\u674e\u5b97\u6d77\u535a\u58eb\u8868\u793a\uff1a\u201c\u57282018\u5e7412\u6708\u4efd\u7684\u7f8e\u570b\u8840\u6db2\u5b78\u5e74\u6703\u4e0a,\u6211\u5011\u7684\u5408\u4f5c\u91ab\u751f\u6c5f\u677e\u798f\u6559\u6388\u5831\u544a\u4e86 CT053 \u5168\u4eba\u6297 BCMA CAR T \u7d30\u80de\u6cbb\u7642\u591a\u767c\u6027\u9aa8\u9ad3\u7624\u60a3\u8005\u5177\u6709\u5341\u5206\u4ee4\u4eba\u9f13\u821e\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002\u6b64\u6b21\u7372\u5f97\u570b\u5bb6\u85e5\u76e3\u5c40\u7684\u81e8\u5e8a\u8a66\u9a57\u8a31\u53ef\u610f\u7fa9\u975e\u51e1\u3002\u64da JAMA ONCOLOGY \u5831\u9053\uff0c2016\u5e74\u5927\u6982\u670913\u842c\u65b0\u767c\u7684\u591a\u767c\u6027\u9aa8\u9ad3\u7624\u75c5\u4f8b\uff0c\u610f\u5473\u8457\u5f9e1990\u5e74\u52302016\u5e74\u5176\u767c\u75c5\u7387\u63d0\u9ad8\u4e86126% \u3002\u76e1\u7ba1\u5df2\u6709\u4e00\u4e9b\u65b0\u7684\u6cbb\u7642\u624b\u6bb5\uff0c\u591a\u767c\u6027\u9aa8\u9ad3\u7624\u4ecd\u7136\u662f\u96e3\u4ee5\u6cbb\u6108\u7684\uff0c\u4ecd\u9700\u8981\u66f4\u52a0\u5148\u9032\u6709\u6548\u7684\u6cbb\u7642\u624b\u6bb5\u3002\u6211\u5011\u71b1\u5207\u671f\u5f85 CT053 CAR-BCMA T \u7d30\u80de\u7684\u81e8\u5e8a\u958b\u767c\u80fd\u5920\u633d\u6551\u3001\u9020\u798f\u66f4\u591a\u7684\u665a\u671f\u591a\u767c\u6027\u9aa8\u9ad3\u7624\u60a3\u8005\u3002\u4f5c\u70ba\u8a72 CT053 \u7814\u767c\u8a08\u5283\u7684\u4e00\u90e8\u5206\uff0c\u6211\u5011\u5c07\u65bc2019\u5e74\u5411\u7f8e\u570b FDA \u905e\u4ea4\u81e8\u5e8a\u8a66\u9a57\u7533\u8acb\u201d\u3002<\/p>\n<p>\u79d1\u6fdf\u751f\u7269\u662f\u4e00\u5bb6\u81e8\u5e8a\u968e\u6bb5\u514d\u75ab\u816b\u7624\u5b78\u516c\u53f8\uff0c\u81f4\u529b\u65bcCAR-T\u7642\u6cd5\u7684\u958b\u767c\u548c\u5546\u696d\u5316\uff0c\u4ee5\u6eff\u8db3\u672a\u6eff\u8db3\u7684\u91ab\u7642\u9700\u6c42\u3002\u8a72\u516c\u53f8\u8207\u4e2d\u570b\u7684\u9802\u7d1a\u91ab\u9662\u5408\u4f5c\uff0c\u63a8\u51fa\u4e86\u5e7e\u9805\u4eba\u9ad4\u7814\u7a76\uff0c\u5982\u7528\u65bc\u6cbb\u7642\u809d\u7d30\u80de\u764c\u548c\u9c57\u72c0\u7d30\u80de\u764c\u7684CAR-GPC3-T\uff0c\u7528\u65bc\u6cbb\u7642\u591a\u5f62\u6027\u81a0\u8cea\u6bcd\u7d30\u80de\u7624\u7684CAR-EGFR \/ EGFRvIII-T\u548c\u6cbb\u7642\u80c3\u764c\u548c\u80f0\u817a\u764c\u7b49\u75be\u75c5\u7684\u81e8\u5e8a\u7814\u7a76\u3002<\/p>\n<p>\u82f1\u6587\u4f86\u6e90\uff1aBiospace<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u79d1\u6fdf\u751f\u7269\u91ab\u85e5\uff08\u4e0a\u6d77\uff09\u6709\u9650\u516c\u53f8\uff08\u79d1\u6fdf\u751f\u7269\uff0cCARsgen Therapeutics\uff09\u662f\u4e00\u5bb6\u81f4\u529b\u65bc\u958b\u767c\u764c\u7665\u5d4c\u5408\u6297\u539f [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":258542,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[426],"tags":[809,927,563,644,570,564],"class_list":["post-258545","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hant","tag-809","tag-927","tag--zh-hant","tag-644","tag-570","tag-564","sectors-life-science-zh-hant","locations-china-zh-hant"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/258545","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=258545"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/258545\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/258542"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=258545"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=258545"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=258545"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}