{"id":267634,"date":"2019-06-03T19:46:47","date_gmt":"2019-06-04T02:46:47","guid":{"rendered":"https:\/\/nai500.com\/?p=267634"},"modified":"2019-06-03T19:46:47","modified_gmt":"2019-06-04T02:46:47","slug":"%e9%98%bf%e6%96%af%e5%88%a9%e5%ba%b7%e5%92%8c%e9%bb%98%e5%85%8b%e6%93%ac%e6%8f%90%e4%ba%a4lynparza%e6%b2%bb%e7%99%82%e8%83%b0%e8%85%ba%e7%99%8c%e7%9a%84%e7%9b%a3%e7%ae%a1%e6%89%b9%e5%87%86","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2019\/06\/%e9%98%bf%e6%96%af%e5%88%a9%e5%ba%b7%e5%92%8c%e9%bb%98%e5%85%8b%e6%93%ac%e6%8f%90%e4%ba%a4lynparza%e6%b2%bb%e7%99%82%e8%83%b0%e8%85%ba%e7%99%8c%e7%9a%84%e7%9b%a3%e7%ae%a1%e6%89%b9%e5%87%86\/","title":{"rendered":"\u963f\u65af\u5229\u5eb7\u548c\u9ed8\u514b\u64ec\u63d0\u4ea4Lynparza\u6cbb\u7642\u80f0\u817a\u764c\u7684\u76e3\u7ba1\u6279\u51c6"},"content":{"rendered":"<p>\u4eca\u5e742\u6708\uff0c\u7e3d\u90e8\u4f4d\u65bc\u82f1\u570b\u7684\u963f\u65af\u5229\u5eb7\u53ca\u5176\u767c\u5c55\u5408\u4f5c\u5925\u4f34\u9ed8\u514b\u516c\u53f8\u9996\u6b21\u5ba3\u4f48\uff0cLynparza\u5728\u7b2c\u4e09\u968e\u6bb5POLO\u8a66\u9a57\u4e2d\u9054\u5230\u4e86\u7d42\u9ede\u3002\u6578\u64da\u986f\u793a\uff0c\u63a5\u53d7Lynparza\u6cbb\u7642\u7684\u60a3\u8005\u5728\u7121\u9032\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u4e2d\u986f\u793a\u51fa\u7d71\u8a08\u5b78\u610f\u7fa9\u548c\u81e8\u5e8a\u610f\u7fa9\u4e0a\u7684\u6539\u5584\u3002\u5728\u9031\u672b\u8209\u884c\u7684\u7f8e\u570b\u816b\u7624\u5b78\u81e8\u5e8a\u5b78\u6703\uff08ASCO\uff09\u4e0a\uff0c\u5169\u5bb6\u516c\u53f8\u767c\u4f48\u4e86\u66f4\u591a\u6578\u64da\uff0c\u986f\u793a\u6578\u64da\u7684\u7a69\u5065\u6027\u3002\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0cLynparza\u5c07\u75be\u75c5\u9032\u5c55\u7684\u98a8\u96aa\u964d\u4f4e\u4e8647%\u3002Lynparza\u6cbb\u7642\u60a3\u8005\u7684\u4e2d\u4f4dPFS\u70ba7.4\u500b\u6708\uff0c\u800c\u5b89\u6170\u5291\u7d44\u70ba3.8\u500b\u6708\u3002<\/p>\n<p>\u963f\u65af\u5229\u5eb7\u7f8e\u570b\u816b\u7624\u5b78\u696d\u52d9\u90e8\u8ca0\u8cac\u4ebaNataf\u8868\u793a\uff0c\u9019\u662fPARP\u6291\u5236\u5291\u9996\u6b21\u5728\u7a2e\u7cfbBRCA\u7a81\u8b8a\u7684\u8f49\u79fb\u6027\u80f0\u817a\u764c\u4e2d\u767c\u63ee\u4f5c\u7528\u3002Lynparza\u53ef\u4ee5\u70ba\u90a3\u4e9b\u88ab\u8a3a\u65b7\u51fa\u60a3\u6709\u6700\u56b4\u91cd\u764c\u75c7\u7684\u60a3\u8005\u5e36\u4f86\u5e0c\u671b\u3002POLO\u8a66\u9a57\u7d50\u679c\u986f\u793a\uff0c\u670d\u7528PARP\u6291\u5236\u5291\u7684\u60a3\u8005\u5728\u516d\u500b\u6708\u6642\u7684\u9032\u5c55\u7387\u662f\u5b89\u6170\u5291\u7d44\u7684\u5169\u500d\u591a\u3002<\/p>\n<p>Nataf\u88dc\u5145\u8aaa\uff0cPOLO\u8a66\u9a57\u7d50\u679c\u9032\u4e00\u6b65\u8b49\u660e\u4e86Lynparza\u53ef\u4ee5\u5728\u591a\u7a2eBRCA\u7a81\u8b8a\u816b\u7624\u985e\u578b\u4e2d\u5e36\u4f86\u81e8\u5e8a\u76ca\u8655\u3002<\/p>\n<p>\u80f0\u817a\u764c\u7684\u65e9\u671f\u8a3a\u65b7\u5f88\u56f0\u96e3\uff0c\u901a\u5e38\u6c92\u6709\u75c7\u72c0\uff0c\u76f4\u5230\u78ba\u8a3a\u6642\u70ba\u6642\u5df2\u665a\u3002\u5927\u7d0480%\u7684\u60a3\u8005\u88ab\u8a3a\u65b7\u70ba\u8f49\u79fb\u671f\u80f0\u817a\u764c\u3002<\/p>\n<p>\u6839\u64da\u8a72\u8a66\u9a57\u7684\u7d50\u679c\uff0c\u963f\u65af\u5229\u5eb7\u548c\u9ed8\u514b\u6b63\u5728\u5c0b\u6c42\u7372\u5f97Lynparza\u7684\u76e3\u7ba1\u6279\u51c6\u3002Lynparza\u5df2\u986f\u793a\u51fa\u5c0d\u6297BRCA\u57fa\u56e0\u7a81\u8b8a\u7684\u529f\u6548\u3002\u96d6\u7136Lynparza\u5c1a\u672a\u7372\u5f97\u6cbb\u7642gBRCAm\u80f0\u817a\u764c\u7684\u6279\u51c6\uff0c\u4f46Lynparza\u5df2\u88ab\u6279\u51c6\u7528\u65bcBRCAm\u665a\u671f\u5375\u5de2\u764c\u7684\u4e00\u7dda\u7dad\u6301\u6cbb\u7642\uff0c\u4ee5\u53ca\u4e4b\u524d\u63a5\u53d7\u904e\u5316\u7642\u6cbb\u7642\u7684\u7a2e\u7cfbBRCAm HER2\u9670\u6027\u8f49\u79fb\u6027\u4e73\u817a\u764c\u3002<\/p>\n<p>\u82f1\u6587\u4f86\u6e90\uff1aBiospace<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4eca\u5e742\u6708\uff0c\u7e3d\u90e8\u4f4d\u65bc\u82f1\u570b\u7684\u963f\u65af\u5229\u5eb7\u53ca\u5176\u767c\u5c55\u5408\u4f5c\u5925\u4f34\u9ed8\u514b\u516c\u53f8\u9996\u6b21\u5ba3\u4f48\uff0cLynparza\u5728\u7b2c\u4e09\u968e\u6bb5POLO\u8a66\u9a57\u4e2d\u9054\u5230 [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":267629,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[426],"tags":[809,927,563,644,570,564],"class_list":["post-267634","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hant","tag-809","tag-927","tag--zh-hant","tag-644","tag-570","tag-564","sectors-life-science-zh-hant","locations-us-zh-hant","exchange-nasdaq-zh-hant","exchange-nyse-zh-hant"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/267634","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=267634"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/267634\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/267629"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=267634"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=267634"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=267634"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}