{"id":297932,"date":"2019-10-11T22:30:08","date_gmt":"2019-10-12T05:30:08","guid":{"rendered":"https:\/\/nai500.com\/?p=297932"},"modified":"2019-10-11T22:31:01","modified_gmt":"2019-10-12T05:31:01","slug":"%e5%ba%b7%e6%a8%b8%e7%94%9f%e7%89%a9%e5%ae%8c%e6%88%90%e7%99%8c%e7%99%a5%e5%85%8d%e7%96%ab%e8%aa%bf%e7%af%80%e5%8a%91%e4%b8%80%e6%9c%9f%e8%a9%a6%e9%a9%97","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2019\/10\/%e5%ba%b7%e6%a8%b8%e7%94%9f%e7%89%a9%e5%ae%8c%e6%88%90%e7%99%8c%e7%99%a5%e5%85%8d%e7%96%ab%e8%aa%bf%e7%af%80%e5%8a%91%e4%b8%80%e6%9c%9f%e8%a9%a6%e9%a9%97\/","title":{"rendered":"\u5eb7\u6a38\u751f\u7269\u5b8c\u6210\u764c\u7665\u514d\u75ab\u8abf\u7bc0\u5291\u4e00\u671f\u8a66\u9a57"},"content":{"rendered":"<p>\u4e0a\u6d77\u5eb7\u6a38\u751f\u7269\u5b8c\u6210\u4e86KPG-818\u7684\u4e00\u671f\u4eba\u9ad4\u8a66\u9a57\u3002KPG-818\u662f\u4e00\u7a2e\u57fa\u65bcCRBN E3\u6cdb\u7d20\u9023\u63a5\u9176\u5fa9\u5408\u7269\u7684\u5c0f\u5206\u5b50\u514d\u75ab\u8abf\u7bc0\u5291\u3002\u5eb7\u6a38\u516c\u53f8\u5e0c\u671bKPG-818\u80fd\u5920\u6709\u6548\u6cbb\u7642\u7cfb\u7d71\u6027\u7d05\u6591\u72fc\u7621\uff08SLE\uff09\u548c\u8840\u6db2\u7cfb\u7d71\u60e1\u6027\u816b\u7624\u3002\u5728\u5065\u5eb7\u53d7\u8a66\u8005\u4e2d\u9032\u884c\u7684\u4e00\u671f\u8a66\u9a57\u4e2d\uff0c\u5eb7\u6a38\u516c\u53f8\u7684KPG-818\u6c92\u6709\u986f\u793a\u4efb\u4f55\u5b89\u5168\u6027\u6216\u8010\u53d7\u6027\u554f\u984c\u3002\u5eb7\u6a38\u751f\u7269\u6b63\u5728\u958b\u767c\u7528\u65bc\u764c\u7665\u3001\u81ea\u8eab\u514d\u75ab\u548c\u708e\u6027\u75be\u75c5\u7684\u65b0\u578b\u5c0f\u5206\u5b50\u85e5\u7269\u3002<\/p>\n<p>\u82f1\u6587\u4f86\u6e90\uff1aChina Biotoday<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Kangpu Biopharma of Shanghai completed a first-in-human US Phase I trial of KPG-818, a small molecule immunomodulator based on the CRBN E3 ubiquitin ligase complex. Kangpu expects KPG-818 will be an effective treatment for systemic lupus erythematosus (SLE) and hematological malignancies. <\/p>\n","protected":false},"author":9,"featured_media":297926,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[426],"tags":[459,644,564],"class_list":["post-297932","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hant","tag-459","tag-644","tag-564","sectors-life-science-zh-hant","locations-china-zh-hant"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/297932","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=297932"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/297932\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/297926"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=297932"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=297932"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=297932"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}