{"id":312897,"date":"2020-01-14T19:41:44","date_gmt":"2020-01-15T03:41:44","guid":{"rendered":"https:\/\/nai500.com\/blog\/2020\/01\/hitgen-enters-into-dna-encoded-library-based-drug-discovery-research-collaboration-with-kymera\/"},"modified":"2020-01-14T19:42:16","modified_gmt":"2020-01-15T03:42:16","slug":"%e4%b8%ad%e5%9c%8b%e6%88%90%e9%83%bd%e5%85%88%e5%b0%8e%e9%81%94%e6%88%90%e6%96%b0%e8%97%a5%e7%a0%94%e7%99%bc%e5%90%88%e4%bd%9c","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2020\/01\/%e4%b8%ad%e5%9c%8b%e6%88%90%e9%83%bd%e5%85%88%e5%b0%8e%e9%81%94%e6%88%90%e6%96%b0%e8%97%a5%e7%a0%94%e7%99%bc%e5%90%88%e4%bd%9c\/","title":{"rendered":"\u4e2d\u570b\u6210\u90fd\u5148\u5c0e\u9054\u6210\u65b0\u85e5\u7814\u767c\u5408\u4f5c"},"content":{"rendered":"<p>\u6210\u90fd\u5148\u5c0e\u5ba3\u4f48\uff0c\u5df2\u8207Kymera Therapeutics\uff0cInc.\u9032\u884c\u4e86\u85e5\u7269\u767c\u73fe\u7814\u7a76\u5408\u4f5c\uff0c\u4ee5\u8b58\u5225Kymera\u611f\u8208\u8da3\u7684\u5c0f\u5206\u5b50\u7dda\u7d22\u3002 \u6210\u90fd\u5148\u5c0e\u5c07\u57fa\u65bcDNA\u7de8\u78bc\u5316\u5408\u7269\u5eab\uff08DEL\uff09\u7684\u8a2d\u8a08\uff0c\u61c9\u7528\u5176\u5e73\u81fa\u6280\u8853\u4f86\u5408\u6210\u548c\u7be9\u9078\u3001\u767c\u73fe\u8207\u67d0\u4e9b\u9776\u6a19\u7d50\u5408\u7684\u5316\u5408\u7269\u3002\u9452\u5b9a\u51fa\u7684\u5316\u5408\u7269\u5c07\u7368\u5bb6\u6388\u6b0a\u7d66Kymera\u3002\u6839\u64da\u8a72\u5354\u8b70\u7684\u689d\u6b3e\uff0c\u6210\u90fd\u5148\u5c0e\u5c07\u6536\u5230\u672a\u62ab\u9732\u7684\u9810\u4ed8\u6b3e\uff0c\u4e26\u5c07\u6709\u8cc7\u683c\u7372\u5f97Kymera\u7684\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002<\/p>\n<p>\u6210\u90fd\u5148\u5c0e\u8463\u4e8b\u6703\u4e3b\u5e2d\u517c\u9996\u5e2d\u57f7\u884c\u5b98Jin Li\u535a\u58eb\u8aaa\uff1a\u201c\u6211\u5011\u671f\u5f85\u8207Kymera\u5408\u4f5c\uff0c\u70ba\u4ed6\u5011\u7684\u7814\u7a76\u751f\u6210\u5148\u5c0e\u5316\u5408\u7269\uff0c\u5c07\u8f49\u5316\u85e5\u7269\u5e36\u7d66\u60a3\u8005\u3002\u5c0d\u65bc\u6211\u5011\u4f86\u8aaa\uff0c\u9019\u662f\u8207\u65b0\u8208\u7684\u86cb\u767d\u8cea\u964d\u89e3\u9818\u57df\u7684\u9818\u5148\u516c\u53f8\u5408\u4f5c\u958b\u767c\u672a\u4f86\u5275\u65b0\u7642\u6cd5\u7684\u7d55\u4f73\u6a5f\u6703\u3002 \u6210\u90fd\u5148\u5c0e\u7684\u6280\u8853\u7d50\u5408\u4e86\u5206\u5b50\u751f\u7269\u5b78\u3001\u7d44\u5408\u5316\u5b78\u3001\u9ad8\u901a\u91cf\u6e2c\u5e8f\u548c\u5148\u9032\u7684\u4fe1\u606f\u5b78\u7684\u5f37\u5927\u529f\u80fd\u3002\u6211\u5011\u76f8\u4fe1\uff0c\u6b64\u6b21\u5408\u4f5c\u5c07\u978f\u56fa\u6210\u90fd\u5148\u5c0e\u5e73\u81fa\u5728\u8fc5\u901f\u767c\u5c55\u7684DNA\u7de8\u78bc\u5316\u5b78\u9818\u57df\u4e2d\u7684\u9818\u5c0e\u8005\u4f5c\u7528\u201d\u3002<\/p>\n<p>Kymera Therapeutics\u662f\u4e00\u5bb6\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u958b\u5275\u4e86\u4e00\u7a2e\u8b8a\u9769\u6027\u7684\u65b0\u65b9\u6cd5\u4f86\u6cbb\u7642\u4ee5\u524d\u7121\u6cd5\u6cbb\u7652\u7684\u75be\u75c5\u3002\u8a72\u516c\u53f8\u6b63\u5728\u63a8\u9032\u6709\u91dd\u5c0d\u6027\u7684\u86cb\u767d\u8cea\u964d\u89e3\u9818\u57df\uff0c\u5229\u7528\u4eba\u9ad4\u56fa\u6709\u7684\u86cb\u767d\u8cea\u56de\u6536\u6a5f\u5236\u4f86\u964d\u89e3\u5931\u8abf\u7684\u81f4\u75c5\u86cb\u767d\u8cea\u3002<\/p>\n<p>\u6210\u90fd\u5148\u5c0e\u662f\u4e00\u5bb6\u5feb\u901f\u767c\u5c55\u7684\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u7e3d\u90e8\u4f4d\u65bc\u4e2d\u570b\u6210\u90fd\uff0c\u5728\u7f8e\u570b\u8a2d\u6709\u5b50\u516c\u53f8\u3002 \u6210\u90fd\u5148\u5c0e\u5efa\u7acb\u4e86\u4e00\u500b\u884c\u696d\u9818\u5148\u7684\u5e73\u81fa\uff0c\u4ee5DNA\u7de8\u78bc\u5316\u5408\u7269\u5eab\uff08DEL\uff09\u70ba\u4e2d\u5fc3\u9032\u884c\u65e9\u671f\u85e5\u7269\u767c\u73fe\u7814\u7a76\u3002\u6210\u90fd\u5148\u5c0e\u7684DNA\u7de8\u78bc\u5316\u5408\u7269\u5eab\u5305\u62ec\u6578\u5104\u65b0\u7a4e\u3001\u591a\u6a23\u3001\u5c0f\u5206\u5b50\u548c\u5927\u74b0\u5316\u5408\u7269\u7684\u7de8\u78bc\u5316\u5408\u7269\u3002<\/p>\n<p>\u82f1\u6587\u4f86\u6e90\uff1aBiospace<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hitgen Ltd today announced that it has entered into a drug discovery research collaboration with Kymera Therapeutics, Inc., to identify small molecule leads against targets of interest to Kymera. HitGen will apply its platform technology, based on the design, synthesis and screening of DNA-encoded libraries (DEL) to discover compounds that bind to certain targets. The identified compounds will be exclusively licensed to Kymera. Under the terms of the agreement, HitGen will receive an undisclosed upfront payment and will be eligible for milestone payments from Kymera.<\/p>\n","protected":false},"author":9,"featured_media":312884,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[426],"tags":[563,644,564],"class_list":["post-312897","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hant","tag--zh-hant","tag-644","tag-564","sectors-life-science-zh-hant"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/312897","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=312897"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/312897\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/312884"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=312897"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=312897"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=312897"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}