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mRNA-1273\u662f\u4e00\u7a2e\u91dd\u5c0d\u65b0\u51a0\u75c5\u6bd2\u7de8\u78bc\u7684Spike (S)\u86cb\u767d\u9810\u878d\u5408\u7a69\u5b9a\u5f62\u5f0f\u7684mRNA\u75ab\u82d7\uff0c\u7531Moderna\u7814\u7a76\u4eba\u54e1\u8207NIAID\u75ab\u82d7\u7814\u7a76\u4e2d\u5fc3\uff08VRC\uff09\u7684\u79d1\u5b78\u5bb6\u5408\u4f5c\u9078\u64c7\u3002\u6279\u751f\u7522\u7684\u8cc7\u91d1\u4f86\u81ea\u6d41\u884c\u75c5\u9632\u7bc4\u5275\u65b0\u806f\u76df\uff08\uff08CEPI\uff09\u3002<\/p>\n
\u8a72\u8a66\u9a57\u6b63\u5728\u897f\u96c5\u5716\u7684Kaiser Permanente\u83ef\u76db\u9813\u5065\u5eb7\u7814\u7a76\u6240\u9032\u884c\u3002\u4eca\u5929\u6709\u7b2c\u4e00\u4f8b\u75c5\u4eba\u3002\u8a72\u8a66\u9a57\u5c07\u63a5\u7a2e\u5305\u62ec45\u540d\u5e74\u8f15\u5065\u5eb7\u7684\u5fd7\u9858\u8005\uff0c\u4ed6\u5011\u5c07\u63a5\u53d7\u4e0d\u540c\u5291\u91cf\u7684\u75ab\u82d7\u3002\u56e0\u70ba\u75ab\u82d7\u4e0d\u5305\u542b\u5be6\u969b\u7684\u65b0\u51a0\u75c5\u6bd2\uff0c\u6240\u4ee5\u53c3\u52a0\u8005\u4e0d\u53ef\u80fd\u88ab\u75ab\u82d7\u611f\u67d3\u3002\u8a72\u6e2c\u8a66\u7684\u76ee\u7684\u662f\u8a55\u4f30\u4efb\u4f55\u5b89\u5168\u6027\u554f\u984c\uff0c\u4e26\u78ba\u5b9a\u9069\u7576\u7684\u5291\u91cf\u4ee5\u523a\u6fc0\u6709\u6548\u7684\u514d\u75ab\u53cd\u61c9\u3002<\/p>\n
\u4e16\u754c\u4e0a\u8a31\u591a\u5176\u4ed6\u516c\u53f8\u548c\u6a5f\u69cb\u4e5f\u5728\u52aa\u529b\u958b\u767c\u91dd\u5c0d\u65b0\u51a0\u75c5\u6bd2\u7684\u75ab\u82d7\uff0c\u5176\u4e2d\u5305\u62ecInovio Pharmaceuticals\uff0c\u8a72\u516c\u53f8\u9810\u8a08\u4e0b\u500b\u6708\u5c07\u5728\u8cd3\u5915\u6cd5\u5c3c\u4e9e\u5927\u5b78\u548c\u5bc6\u8607\u88e1\u5dde\u582a\u85a9\u65af\u5e02\u7684\u6e2c\u8a66\u4e2d\u5fc3\u958b\u59cb\u8a66\u9a57\u3002<\/p>\n
\u518d\u751f\u5143\u548c\u8cfd\u8afe\u83f2\uff08Sanofi\uff09\u5df2\u5728\u91cd\u75c7\u4f4f\u9662\u65b0\u51a0\u80ba\u708e\u60a3\u8005\u4e2d\u555f\u52d5\u4e86Kevzara\uff08sarilumab\uff09\u7684\u7f8e\u570b\u81e8\u5e8a\u8a66\u9a57\u3002\u5b83\u5c07\u5728\u7f8e\u570b\u7d0416\u500b\u5730\u9ede\u6e2c\u8a66400\u540d\u60a3\u8005\u3002<\/p>\n
\u5409\u5229\u5fb7\u79d1\u5b78\u516c\u53f8\uff08Gilead Sciences\uff09\u5ba3\u4f48\u5c07\u91dd\u5c0d\u8a3a\u65b7\u60a3\u6709\u65b0\u51a0\u75c5\u6bd2\u7684\u6210\u5e74\u4eba\u958b\u5c55\u6297\u75c5\u6bd2\u85e5\u7269\u745e\u5fb7\u6614\u97cb\u7684\u5169\u9805III\u671f\u81e8\u5e8a\u8a66\u9a57\u3002<\/p>\n
\u9019\u4e9b\u516c\u53f8\u901a\u5e38\u81f4\u529b\u65bc\u4f7f\u7528\u4e0d\u540c\u7684\u65b9\u6cd5\u4f86\u958b\u767c\u75ab\u82d7\uff0c\u9019\u5c07\u5177\u6709\u4e0d\u540c\u7684\u751f\u7522\u6642\u9593\u8868\u548c\u4e0d\u540c\u7684\u6548\u529b\u6c34\u5e73\u3002\u64da\u300a\u8ca1\u5bcc\u300b\u96dc\u8a8c\u5831\u9053\uff0c\u4e00\u4e9b\u7814\u7a76\u4eba\u54e1\u6b63\u5728\u7814\u7a76\u81e8\u6642\u75ab\u82d7\uff0c\u9019\u4e9b\u81e8\u6642\u75ab\u82d7\u53ef\u80fd\u6703\u5728\u958b\u767c\u66f4\u6301\u4e45\u7684\u75ab\u82d7\u6642\u63d0\u4f9b\u6578\u6708\u7684\u4fdd\u8b77\u3002<\/p>\n
Moderna mRNA\u65b9\u6cd5\u7684\u4e00\u9805\u512a\u52e2\u662f\u5176\u958b\u767c\u901f\u5ea6\u3002\u8a72\u75c5\u6bd2\u57281\u67087\u65e5\u548c1\u670813\u65e5\u7372\u5f97\u9452\u5b9a\uff0c\u7f8e\u570b\u570b\u7acb\u885b\u751f\u7814\u7a76\u9662\u548cModerna\u7814\u7a76\u4eba\u54e1\u5df2\u7d93\u63d0\u51fa\u4e86\u8a72\u75ab\u82d7\u7684mRNA\u5e8f\u5217\uff0c\u4e26\u5728\u653f\u5e9c\u6587\u4ef6\u4e2d\u5beb\u9053\uff1a\u201c\u6211\u5011\u5df2\u52d5\u54e1\u8d77\u4f86\u9032\u884c\u81e8\u5e8a\u751f\u7522\u3002\u201d2\u670824\u65e5\u81f325\u65e5\uff0c\u4ed6\u5011\u5c07\u75ab\u82d7\u5f9e\u99ac\u85a9\u8af8\u585e\u5dde\u8afe\u4f0d\u5fb7\u5e02\u7684\u88fd\u9020\u5de5\u5ee0\u904b\u9001\u5230\u99ac\u88e1\u862d\u5dde\u7684NIAID\u3002<\/p>\n
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