{"id":450039,"date":"2023-01-22T23:24:41","date_gmt":"2023-01-23T07:24:41","guid":{"rendered":"https:\/\/nai500.com\/blog\/2023\/01\/%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1%e7%a5%a8-bluebird-bio-crispr-therapeutics\/"},"modified":"2023-01-22T23:24:53","modified_gmt":"2023-01-23T07:24:53","slug":"%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e8%82%a1%e7%a5%a8-bluebird-bio-crispr-therapeutics","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2023\/01\/%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e8%82%a1%e7%a5%a8-bluebird-bio-crispr-therapeutics\/","title":{"rendered":"\u57fa\u56e0\u7de8\u8f2f\u80a1\u7968\u4e8c\u9078\u4e00\uff0c\u8a72\u9078Bluebird Bio\u9084\u662fCRISPR Therapeutics\uff1f"},"content":{"rendered":"

2023\u5e74\uff0c\u9019\u5169\u96bb\u57fa\u56e0\u7de8\u8f2f\u80a1\u7968\u6709\u671b\u8fce\u4f86\u7a81\u7834<\/h2>\n

\u751f\u7269\u79d1\u6280\u516c\u53f8Bluebird bio Inc\uff08NASDAQ:BLUE\uff09<\/a>\u548cCRISPR Therapeutics AG\uff08NASDAQ:CRSP\uff09<\/a>\u5c08\u6ce8\u65bc\u6cbb\u7642\u7f55\u898b\u8840\u6db2\u75c5\u548c\u764c\u75c7\u7684\u57fa\u56e0\u7de8\u8f2f\u7642\u6cd5\uff0c\u4e26\u4e14\u9019\u5169\u96bb\u57fa\u56e0\u7de8\u8f2f\u80a1\u7968\u7684\u80a1\u50f92023\u5e74\u6709\u671b\u8fce\u4f86\u53cd\u5f48\uff0c\u5176\u4e2dBluebird\u7684\u80a1\u50f9\u904e\u53bb1\u5e74\u4e0b\u8dcc\u8d85\u904e16%\u4f46\u904e\u53bb3\u500b\u6708\u4e0a\u6f32\u8d85\u904e8%\uff0cCRISPR\u7684\u80a1\u50f9\u904e\u53bb1\u5e74\u4e0b\u8dcc\u8d85\u904e27%\u4f46\u904e\u53bb3\u500b\u6708\u4e0a\u6f32\u8d85\u904e8%\u3002<\/p>\n

\u9019\u5169\u5bb6\u516c\u53f8\u5747\u672a\u76c8\u5229\uff0c\u4e0a\u4e00\u5b63\u5ea6\u7684\u5408\u4f5c\u6536\u5165\u5728$10\u842c\u5de6\u53f3\u3002\u4e0d\u904e\uff0cBluebird Bio\u9084\u662fCRISPR Therapeutics\u7684\u5728\u7814\u85e5\u7269\u524d\u666f\u90fd\u5f88\u4e0d\u932f\u3002\u5982\u679c\u8981\u8ad6\u9577\u671f\u6295\u8cc7\u50f9\u503c\uff0c\u9019\u5169\u96bb\u57fa\u56e0\u7de8\u8f2f\u751f\u7269\u79d1\u6280\u80a1\u7968\u8ab0\u624d\u662f\u66f4\u597d\u7684\u9078\u64c7\uff1f<\/p>\n

\u9078\u64c7Bluebird Bio\u7684\u7406\u7531<\/h2>\n

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\u53bb\u5e748\u6708\uff0cBluebird\u6cbb\u7642\u7f55\u898b\u907a\u50b3\u8840\u6db2\u75c5\u8f38\u8840\u4f9d\u8cf4\u6027\u03b2\u5730\u4e2d\u6d77\u8ca7\u8840\u7684\u4e00\u6b21\u6027\u6cbb\u7652\u7642\u6cd5Zynteglo\uff08\u5b9a\u50f9$280\u842c\uff09\u7372\u5f97FDA\u6279\u51c6\uff0c\u8a72\u516c\u53f8\u672c\u6708\u8868\u793a\u8a72\u85e5\u7269\u9810\u8a08\u5c07\u5f9e2023\u5e74\u4e00\u5b63\u5ea6\u8d77\u5275\u9020\u6536\u5165\u3002\u8a72\u516c\u53f8\u7684\u53e6\u4e00\u6b3e\u85e5\u7269Skysona\u53bb\u5e749\u6708\u7372\u6279\u6cbb\u7642\u8166\u814e\u4e0a\u817a\u8166\u767d\u8cea\u71df\u990a\u4e0d\u826f\uff08CALD\uff09\uff0c\u9019\u4e5f\u662f\u5168\u7403\u6700\u6602\u8cb4\u7684\u85e5\u7269\uff08\u5b9a\u50f9$300\u842c\uff09\u3002\u96d6\u7136\u03b2\u5730\u4e2d\u6d77\u8ca7\u8840\u548cCALD\u7684\u60a3\u8005\u4eba\u6578\u6709\u9650\uff0c\u4f46\u9ad8\u5b9a\u50f9\u5c07\u6709\u52a9\u65bc\u8a72\u516c\u53f8\u5be6\u73fe\u76c8\u8667\u5e73\u8861\u3002<\/p>\n

\u6b64\u5916\uff0cBluebird\u7684\u53e6\u4e00\u6b3e\u5f8c\u671f\u7642\u6cd5\u662f\u6cbb\u7642\u942e\u72c0\u7d30\u80de\u75c5\uff08SCD\uff09\u7684lovo-cel\uff0c\u8a72\u516c\u53f8\u9810\u8a082023\u5e74\u4e00\u5b63\u5ea6\u5411\u7f8e\u570bFDA\u63d0\u4ea4\u9019\u4e00\u4e00\u6b21\u6027\u6cbb\u7652\u7642\u6cd5\u7684\u751f\u7269\u88fd\u5291\u8a31\u53ef\u7533\u8acb\uff08BLA\uff09\u3002<\/p>\n

\u9078\u64c7CRISPR Therapeutics\u7684\u7406\u7531<\/h2>\n

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CRISPR\u7684\u9996\u5e2d\u7642\u6cd5\u662f\u806f\u5408\u798f\u6cf0\u88fd\u85e5Vertex Pharmaceuticals\uff08NASDAQ:VRTX\uff09\u958b\u767c\u7684\u57fa\u56e0\u7de8\u8f2f\u7642\u6cd5exa-cel\u3002exa-cel\u5b9a\u50f9\u53ef\u80fd\u4f4e\u65bc$280\u842c\uff0c\u540c\u6642\u8a66\u9a57\u7d50\u679c\u986f\u793a\u5176\u6709\u6548\u6027\u4e5f\u66f4\u597d\uff0c\u56e0\u6b64\u5982\u679c\u8a72\u7642\u6cd5\u4eca\u5e74\u7372\u5f97FDA\u6279\u51c6\u5c07\u5c0dZynteglo\u5f62\u6210\u7af6\u722d\u512a\u52e2\u3002exa-cel\u7684\u6536\u5165\u5206\u6210CRISPR\u548c\u798f\u6cf0\u88fd\u85e5\u5404\u536040%\u548c60%\uff0c\u4e26\u4e14\u5169\u5bb6\u516c\u53f8\u5df2\u7d93\u5728\u6b50\u6d32\u548c\u82f1\u570b\u63d0\u4ea4\u4e86\u6279\u51c6\u7533\u8acb\uff0c\u540c\u6642\u7f8e\u570b\u7684\u6efe\u52d5\u7533\u8acb\u5c07\u57282023\u5e74\u4e00\u5b63\u5ea6\u5e95\u5b8c\u6210\u3002<\/p>\n

\u6700\u5f8c\uff0c\u76f8\u6bd4Bluebird\uff0cCRISPR\u5728\u7814\u85e5\u7269\u7684\u6578\u91cf\u66f4\u591a\uff0c\u7a2e\u985e\u66f4\u591a\u6a23\uff0c\u5176\u4e2dCAR T-\u7d30\u80de\u57fa\u56e0\u7642\u6cd5CTX110\u55ae\u5291\u6cbb\u7642\u96e3\u6cbb\u6027\u548c\u5fa9\u767c\u6027\u5927B\u7d30\u80de\u6dcb\u5df4\u7624\u7684\u7d50\u679c\u7a4d\u6975\u3002\u53e6\u4e00\u6b3e\u540c\u7a2e\u7570\u9ad4CAR T-\u7d30\u80de\u57fa\u56e0\u7642\u6cd5CTX130\u6cbb\u7642\u5fa9\u767c\u6027\u6216\u96e3\u6cbb\u6027T\u6216B\u7d30\u80de\u60e1\u6027\u816b\u7624\u7684\u521d\u671f\u8a66\u9a57\u7d50\u679c\u4e5f\u975e\u5e38\u4e0d\u932f\uff0c\u5177\u5099\u91cd\u78c5\u85e5\u7684\u6f5b\u529b\u3002<\/p>\n

\u9078\u64c7\u986f\u800c\u6613\u898b<\/h2>\n

Bluebird Bio\u5728\u85e5\u54c1\u5be9\u6279\u65b9\u9762\u5df2\u7d93\u9818\u5148\uff0c\u4f46CRISPR\u6191\u85c9\u5176exa-cel\u7684\u6709\u6548\u6027\uff0c\u66f4\u5145\u88d5\u7684\u73fe\u91d1\u4ee5\u53ca\u66f4\u9f90\u5927\u7684\u5728\u7814\u85e5\u7269\uff0c\u9577\u671f\u6f5b\u529b\u66f4\u5927\u3002\u6b64\u5916\uff0cCRISPR\u5728\u4e26\u8cfc\u6d88\u606f\u65b9\u9762\u4e5f\u66f4\u591a\u88ab\u63d0\u53ca\uff0c\u9019\u5c0d\u73fe\u6709\u80a1\u6771\u4e5f\u662f\u4e00\u500b\u5de8\u5927\u7684\u6f5b\u5728\u5229\u597d\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

2023\u5e74\uff0c\u9019\u5169\u96bb\u57fa\u56e0\u7de8\u8f2f\u80a1\u7968\u6709\u671b\u8fce\u4f86\u7a81\u7834 \u751f\u7269\u79d1\u6280\u516c\u53f8Bluebird bio Inc\uff08NASDAQ:BLU […]<\/p>\n","protected":false},"author":27,"featured_media":448947,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1522,431],"tags":[809,927,563,564],"class_list":["post-450039","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1522","category-trends-strategies-zh-hant","tag-809","tag-927","tag--zh-hant","tag-564","sectors-life-science-zh-hant","locations-us-zh-hant","exchange-nasdaq-zh-hant"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/450039","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=450039"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/450039\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/448947"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=450039"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=450039"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=450039"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}