{"id":476423,"date":"2023-10-31T17:30:11","date_gmt":"2023-11-01T00:30:11","guid":{"rendered":"https:\/\/nai500.com\/blog\/2023\/10\/%e4%b8%ad%e5%9b%bd-pd-1%e5%8d%95%e6%8a%97-fda%e6%89%b9%e5%87%86-%e7%be%8e%e5%9b%bd%e5%8c%bb%e7%96%97%e8%82%a1\/"},"modified":"2023-10-31T17:30:29","modified_gmt":"2023-11-01T00:30:29","slug":"%e4%b8%ad%e5%9c%8b-pd-1%e5%96%ae%e6%8a%97-fda%e6%89%b9%e5%87%86-%e7%be%8e%e5%9c%8b%e9%86%ab%e7%99%82%e8%82%a1","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2023\/10\/%e4%b8%ad%e5%9c%8b-pd-1%e5%96%ae%e6%8a%97-fda%e6%89%b9%e5%87%86-%e7%be%8e%e5%9c%8b%e9%86%ab%e7%99%82%e8%82%a1\/","title":{"rendered":"\u4e2d\u570b\u81ea\u4e3b\u7814\u767c\u7684PD-1\u55ae\u6297\u7d42\u65bc\u7372\u5f97FDA\u6279\u51c6\uff0c\u9019\u53ea\u7f8e\u570b\u91ab\u7642\u80a1\u80a1\u50f9\u66b4\u6f32"},"content":{"rendered":"<p>\u9031\u4e00\uff0c\u816b\u7624\u514d\u75ab\u7642\u6cd5\u958b\u767c\u516c\u53f8<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=CHRS\">Coherus BioSciences Inc\uff08NASDAQ:CHRS\uff09<\/a>\u7684\u80a1\u50f9\u6536\u6f3214%\uff0c\u6b64\u524d\u8a72\u516c\u53f8\u9023\u540c\u4e2d\u570b\u5408\u4f5c\u5925\u4f34\u541b\u5be6\u751f\u7269\u5ba3\u4f48\u671f\u5f85\u5df2\u4e45\u7684\u9f3b\u54bd\u764c\uff08NPC\uff09\u85e5\u7269\uff0cPD-1\u55ae\u6297\u85e5\u7269Loqtorzi\u7d42\u65bc\u7372\u5f97\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u7684\u6279\u51c6\u3002<\/p>\n<h2>Loqtorzi\u6210\u70ba\u9996\u500b\u7372\u5f97FDA\u6279\u51c6\u7684\u9f3b\u54bd\u764c\u85e5\u7269<\/h2>\n<p>\u5728\u6ce8\u660e\u65e5\u671f\u70ba\u4e0a\u9031\u4e94\u7684\u516c\u544a\u4e2d\uff0cCoherus\u9023\u540c\u4e0a\u6d77\u541b\u5be6\u751f\u7269\u91ab\u85e5\u79d1\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8\u5ba3\u4f48\u7f8e\u570bFDA\u5df2\u7d93\u6279\u51c6PD-1\u55ae\u6297\u7279\u745e\u666e\u5229\u55ae\u6297Loqtorzi\uff08toripalimab-tpzi\uff09\u7528\u65bc\u5fa9\u767c\u6027\u6216\u8f49\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u5168\u7dda\u6cbb\u7642\u3002\u9f3b\u54bd\u764c\u662f\u4e00\u7a2e\u7f55\u898b\u7684\u982d\u9838\u90e8\u816b\u7624\uff0c\u767c\u751f\u65bc\u9f3b\u54bd\u90e8\u9ecf\u819c\u4e0a\u76ae\u3002<\/p>\n<p>Loqtorzi\u7684\u7372\u6279\u662f\u57fa\u65bcCoherus\u7684JUPITER-02\u4e09\u671f\u7814\u7a76\u4ee5\u53caPOLARIS-02\u4e8c\u671f\u7814\u7a76\u7684\u7d50\u679c\uff0c\u800c\u4e14\u7121\u8ad6\u60a3\u8005\u7684PD-L1\u72c0\u614b\uff08\u6e2c\u91cf\u764c\u7d30\u80de\u4e0a\u963b\u6b62\u4f60\u7684\u514d\u75ab\u7cfb\u7d71\u653b\u64ca\u764c\u75c7\u7684\u4e00\u7a2e\u86cb\u767d\u8cea\u7684\u6aa2\u6e2c\uff09\u3002Loqtorzi\u662f\u4e0b\u4e00\u4ee3\u7a0b\u5e8f\u6027\u6b7b\u4ea1\u53d7\u9ad41\uff08PD-1\uff09\u55ae\u514b\u9686\u6297\u9ad4\uff0c\u901a\u904e\u963b\u65b7PD-1\u914d\u9ad4PD-L1\u548cPD-L2\u6fc0\u6d3b\u60a3\u8005\u7684\u514d\u75ab\u7cfb\u7d71\u4e26\u6bba\u6b7b\u816b\u7624\u3002<\/p>\n<p>\u7279\u745e\u666e\u5229\u55ae\u6297\u662f\u4e2d\u570b\u9996\u500b\u7372\u6279\u7684\u6297PD-1\u85e5\u7269\uff0c\u96d6\u71365\u5e74\u4e4b\u5f8c\u624d\u5728\u7f8e\u570b\u7372\u6279\uff0c\u4f46Loqtorzi\u4f9d\u7136\u5275\u9020\u4e86\u6b77\u53f2\uff0c\u6210\u70ba\u4e86\u9996\u500b\u7372\u5f97FDA\u6279\u51c6\u4e26\u9032\u5165\u7f8e\u570b\u5e02\u5834\u7684\u9f3b\u54bd\u764c\u85e5\u7269\u3002<\/p>\n<h2>Loqtorzi\u7684\u4e0a\u5e02\u65e5\u671f\u3001\u5b9a\u50f9\u4ee5\u53caCoherus\u7684\u4e0b\u4e00\u6b65<\/h2>\n<p>Coherus\u7684\u9996\u5e2d\u57f7\u884c\u5b98Denny Lanfear\u5c07Loqtorzi\u7684\u7372\u6279\u7a31\u70ba\u201cCoherus\u4f5c\u70ba\u4e00\u5bb6\u5275\u65b0\u816b\u7624\u516c\u53f8\u7684\u95dc\u9375\u4e8b\u4ef6\u201d\uff0c\u4e26\u7a31\u8a72\u516c\u53f8\u63a5\u4e0b\u4f86\u5c07\u628a\u5b83\u7684\u95dc\u6ce8\u9ede\u653e\u5728Loqtorzi\u6cbb\u7642\u5176\u4ed6\u591a\u7a2e\u985e\u578b\u816b\u7624\u7684\u958b\u767c\u4e0a\u3002<\/p>\n<p>\u5728\u4e0a\u9031\u4e94\u7684\u6295\u8cc7\u8005\u96fb\u8a71\u6703\u8b70\u671f\u9593\uff0cLanfear\u8868\u793aCoherus\u201c\u5c07\u4e0d\u6703\u53c3\u8207\u8a72\u6cbb\u7642\u7684\u4f4e\u50f9\u7b56\u7565\u201d\u3002\u9019\u4e5f\u7b26\u5408\u4e2d\u570b\u672c\u571f\u958b\u767c\u85e5\u7269\u7684\u5b9a\u50f9\u8da8\u52e2\uff0c\u5373\u50f9\u683c\u5927\u5e45\u4f4e\u65bc\u897f\u65b9\u570b\u5bb6\u7af6\u722d\u5c0d\u624b\u7684\u985e\u4f3c\u6cbb\u7642\u3002\u5047\u8a2d\u4e00\u5207\u90fd\u6309\u7167\u8a08\u5283\u9032\u884c\uff0cCoherus\u9810\u8a08Loqtorzi\u5c07\u57282024\u5e74\u4e00\u5b63\u5ea6\u6b63\u5f0f\u4e0a\u5e02\uff0c\u5c46\u6642\u8a72\u516c\u53f8\u5c07\u63d0\u4f9b\u7522\u54c1\u5b9a\u50f9\u7684\u66f4\u591a\u7d30\u7bc0\u3002<\/p>\n<p>\u8207\u6b64\u540c\u6642\uff0cCoherus\u7684\u80a1\u50f9\u4eca\u5e74\u8fc4\u4eca\u4f9d\u7136\u4e0b\u8dcc\u8d85\u904e60%\uff0c\u56e0\u6b64\u4eca\u5929\u8a72\u80a1\u80a1\u50f9\u7684\u53cd\u5f48\u4e26\u4e0d\u8b93\u4eba\u610f\u5916\u3002\u5c0d\u65bc\u6709\u8010\u5fc3\uff0c\u9858\u610f\u5efa\u5009\u6216\u589e\u6301Coherus\u7684\u6295\u8cc7\u8005\u4f86\u8aaa\uff0c\u8a72\u516c\u53f8\u672a\u4f86\u5c07\u805a\u7126\u65bc\u64f4\u5927Loqtorzi\u7684\u816b\u7624\u9069\u61c9\u75c7\uff0c\u524d\u666f\u53ef\u671f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u9031\u4e00\uff0c\u816b\u7624\u514d\u75ab\u7642\u6cd5\u958b\u767c\u516c\u53f8Coherus BioSciences Inc\uff08NASDAQ:CHRS\uff09\u7684\u80a1\u50f9\u6536\u6f321 [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":474777,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1522,431],"tags":[801,927,2233,564],"class_list":["post-476423","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1522","category-trends-strategies-zh-hant","tag-801","tag-927","tag-2233","tag-564","sectors-life-science-zh-hant","locations-china-zh-hant","locations-us-zh-hant","exchange-nasdaq-zh-hant"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/476423","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=476423"}],"version-history":[{"count":0,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/476423\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/474777"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=476423"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=476423"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=476423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}