{"id":476746,"date":"2023-11-02T18:26:38","date_gmt":"2023-11-03T01:26:38","guid":{"rendered":"https:\/\/nai500.com\/blog\/2023\/11\/%e5%88%9b%e6%96%b0%e5%88%9b%e9%80%a0%e8%b4%a2%e5%af%8c-%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1%e7%a5%a8-%e5%8c%bb%e7%96%97%e5%88%9b%e6%96%b0%e7%9a%84%e6%9c%80%e5%89%8d%e6%b2%bf\/"},"modified":"2023-11-02T18:27:00","modified_gmt":"2023-11-03T01:27:00","slug":"%e5%89%b5%e6%96%b0%e5%89%b5%e9%80%a0%e8%b2%a1%e5%af%8c-%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e8%82%a1%e7%a5%a8-%e9%86%ab%e7%99%82%e5%89%b5%e6%96%b0%e7%9a%84%e6%9c%80%e5%89%8d%e6%b2%bf","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2023\/11\/%e5%89%b5%e6%96%b0%e5%89%b5%e9%80%a0%e8%b2%a1%e5%af%8c-%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e8%82%a1%e7%a5%a8-%e9%86%ab%e7%99%82%e5%89%b5%e6%96%b0%e7%9a%84%e6%9c%80%e5%89%8d%e6%b2%bf\/","title":{"rendered":"\u5275\u65b0\u5275\u9020\u8ca1\u5bcc\uff0c\u800c\u9019\u53ea\u57fa\u56e0\u7de8\u8f2f\u80a1\u7968\u6b63\u597d\u7ad9\u5728\u4e86\u91ab\u7642\u5275\u65b0\u7684\u6700\u524d\u6cbf"},"content":{"rendered":"

\u53ea\u8981\u9078\u5c0d\u80a1\u7968\uff0c\u88fd\u85e5\u884c\u696d\u4e00\u76f4\u4ee5\u4f86\u90fd\u662f\u6295\u8cc7\u8005\u7372\u53d6\u8d85\u7d1a\u56de\u5831\u7684\u4e00\u5927\u4f86\u6e90\u3002\u4e8c\u6230\u4ee5\u4f86\uff0c\u7f8e\u570b\u80a1\u5e02\u6f32\u5e45\u6700\u5927\u768430\u53ea\u80a1\u7968\u7576\u4e2d\uff0c5\u53ea\u5c31\u5c6c\uffff\u88fd\u85e5\u5546\uff0c\u5176\u4e2d\u6709\u4e9b\u516c\u53f8\u5728\u76f8\u5c0d\u8f03\u77ed\u7684\u6642\u9593\u5167\u5c31\u5be6\u73fe\u4e86\u9019\u4e00\u6210\u5c31\u3002<\/p>\n

\u6bd4\u5982\u8aaa\uff0c\u5982\u679c1981\u5e74\u6295\u8cc7\u8f1d\u745e\u88fd\u85e5Pfizer\uff08NYSE:PFE\uff091\u842c\u7f8e\u5143\uff0c\u62ff\u5230\u73fe\u5728\u9019\u7b46\u521d\u59cb\u6295\u8cc7\u5df2\u7d93\u8d85\u904e100\u842c\u7f8e\u5143\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u540c\u6a23\u7684\u4e00\u7b46\u9322\u6295\u8cc7\u8868\u73fe\u6700\u597d\u7684\u5171\u540c\u57fa\u91d1\uff0c\u6700\u7d42\u4e5f\u7a81\u7834\u4e0d\u4e8690\u842c\u7f8e\u5143\u3002<\/p>\n

\u88fd\u85e5\u80a1\u7968\u5275\u9020\u8ca1\u5bcc\u5947\u8de1\u7684\u79d8\u8a23\u662f\u4ec0\u9ebc\uff1f\u9019\u4e9b\u9ad8\u6210\u9577\u80a1\u7968\u8d85\u51e1\u589e\u9577\u7684\u9a45\u52d5\u529b\u53c8\u662f\u4ec0\u9ebc\uff1f\u9019\u500b\u554f\u984c\u7684\u7b54\u6848\u6709\u5f88\u591a\uff0c\u6bd4\u5982\u8aaa\u5168\u7403\u4eba\u53e3\u7684\u8001\u9f61\u5316\u5e36\u52d5\u91ab\u7642\u9700\u6c42\u6301\u7e8c\u589e\u9577\uff0c\u6216\u8005\u662f\u5168\u7403\u91ab\u7642\u8a2d\u5099\u7684\u65e5\u76ca\u666e\u53ca\uff0c\u4f46\u6700\u91cd\u8981\u7684\u56e0\u7d20\u662f\u5275\u65b0\u3002<\/p>\n

\u5728\u65b0\u6280\u8853\u7684\u52a9\u529b\u4e4b\u4e0b\uff0c\u539f\u672c\u4ee5\u70ba\u7121\u6cd5\u91ab\u6cbb\u7684\u75be\u75c5\u88ab\u4e0d\u65b7\u653b\u7834\uff0c\u800c\u9019\u4e9b\u5be6\u73fe\u5275\u65b0\u7684\u9f8d\u982d\u516c\u53f8\uff0c\u6bd4\u5982\u8aaa\u5b89\u9032Amgen\uff08NASDAQ:AMGN\uff09\u548c\u518d\u751f\u5143\u88fd\u85e5Regeneron Pharmaceuticals\uff08NASDAQ:REGN\uff09\u5728\u9019\u4e00\u904e\u7a0b\u4e2d\u5275\u9020\u51fa\u4e86\u5de8\u5927\u7684\u8ca1\u5bcc\u3002<\/p>\n

CRISPR\/Cas9\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\uff0c\u91ab\u7642\u5275\u65b0\u7684\u65b0\u524d\u6cbf<\/h2>\n

\u55ae\u514b\u9686\u6297\u9ad4\u4ee5\u53ca\u985e\u4f3c\u6280\u8853\u51fa\u73fe\u4e4b\u5f8c\uff0c\u91ab\u7642\u884c\u696d\u5c07\u8fce\u4f86\u53e6\u4e00\u9805\u6709\u671b\u6210\u70ba\u8ca1\u5bcc\u52a0\u901f\u5668\u7684\u5275\u65b0\u6280\u8853\uff0c\u4e5f\u5c31\u662fCRISPR\/Cas9\u57fa\u56e0\u7de8\u8f2f\u3002<\/p>\n

\u96d6\u7136\u73fe\u5728\u5e02\u5834\u4e0a\u7684\u57fa\u56e0\u7de8\u8f2f\u4e0a\u5e02\u516c\u53f8\u4e5f\u4e0d\u5c11\uff0c\u4f46\u5f9e\u8cc7\u672c\u589e\u503c\u6f5b\u529b\u51fa\u767c\uff0cIntellia Therapeutics Inc\uff08NASDAQ:NTLA\uff09<\/a>\u7d55\u5c0d\u662f\u5176\u4e2d\u7684\u4f7c\u4f7c\u8005\u3002\u8a72\u57fa\u56e0\u7642\u6cd5\u516c\u53f8\u806f\u624b\u518d\u751f\u5143\u88fd\u85e5Regeneron Pharmaceuticals\uff08NASDAQ:REGN\uff09\u958b\u5c55\u7684NTLA-2001\u6cbb\u7642\u8f49\u7532\u72c0\u817a\u7d20\u86cb\u767d\uff08ATTR\uff09\u6fb1\u7c89\u6a23\u8b8a\u6027\u7684\u7814\u767c\u9805\u76ee\u5e74\u5e95\u524d\u5c07\u9032\u5165\u95dc\u9375\u7684\u4e09\u671f\u7814\u7a76\u3002<\/p>\n

Intellia\u771f\u7684\u9019\u9ebc\u725b\u55ce\uff1f\u904e\u53bb24\u500b\u6708\uff0c\u6295\u8cc7\u8005\u66f4\u52a0\u95dc\u6ce8\u516c\u53f8\u7684\u57fa\u672c\u9762\uff0c\u751f\u7269\u79d1\u6280\u80a1\u7968\u7684\u4f30\u503c\u88ab\u64e0\u58d3\uff0c\u9019\u53ea\u57fa\u56e0\u7de8\u8f2f\u80a1\u7968\u7684\u50f9\u683c\u904e\u53bb12\u500b\u6708\u4e5f\u66b4\u8dcc52%\u3002\u4f46\u662f\uff0c\u9019\u53ea\u80a1\u7968\u7684\u771f\u6b63\u5438\u5f15\u529b\u5728\u65bc\u5b83\u7684\u6df1\u5ea6\u50f9\u503c\u4e3b\u5f35\u3002\u8a72\u516c\u53f8\u5728\u7814\u85e5\u7269\u6578\u91cf\u591a\uff0c\u672a\u4f8610\u5e74\u5167\u6709\u671b\u62ff\u51fa3\u500b\u751a\u81f3\u662f4\u500b\u91cd\u78c5\u7642\u6cd5\u3002<\/p>\n

\u7576\u7136\u4e86\uff0cCRISPR\/Cas9\u5728\u81e8\u5e8a\u4e0a\u9084\u6709\u5f88\u591a\u6771\u897f\u9700\u8981\u8b49\u660e\uff0c\u9019\u4e00\u770b\u6f32\u8a2d\u60f3\u4e5f\u4e0d\u662f\u9435\u677f\u91d8\u91d8\u7684\u7d50\u8ad6\u3002\u4f46\u662f\uff0c\u6295\u8cc7\u8005\u5c07\u898b\u8b49\u4e00\u500b\u65b0\u7684\u91cd\u5927\u91ab\u7642\u5275\u65b0\u7684\u8a95\u751f\uff0c\u9019\u7a2e\u53ef\u80fd\u6027\u662f\u771f\u771f\u5be6\u5be6\u5b58\u5728\u7684\uff0c\u4f46\u76ee\u524d\u7684\u5e02\u5834\u4e26\u672a\u5c0d\u6b64\u4e88\u4ee5\u53cd\u61c9\u3002<\/p>\n

Intellia\u80a1\u7968\u76ee\u524d\u7684\u5e02\u503c\u9084\u4e0d\u5230\u5eab\u5b58\u73fe\u91d1\u76843\u500d\uff0c\u8070\u660e\u7684\u6295\u8cc7\u8005\u53ef\u4ee5\u9022\u4f4e\u8cb7\u5165\u9019\u53ea\u57fa\u56e0\u7de8\u8f2f\u80a1\u7968\u3002\u4e0d\u7ba1\u600e\u9ebc\u8aaa\uff0c\u904e\u53bb80\u5e74\u6700\u725b\u7684\u725b\u80a1\u4e5f\u6703\u56e0\u70ba\u5e02\u5834\u60c5\u7dd2\u7684\u8b8a\u5316\u51fa\u73fe\u80a1\u50f9\u7684\u6f32\u8dcc\uff0c\u4f46\u5b83\u5011\u6700\u7d42\u90fd\u70ba\u65e9\u671f\u80a1\u6771\u5275\u9020\u4e86\u6539\u8b8a\u4eba\u751f\u7684\u6536\u76ca\u3002<\/p>\n

\u5c0f\u7d50<\/h2>\n

Intellia\u96d6\u7136\u6709\u98a8\u96aa\uff0c\u4f46\u5177\u5099\u8b93\u6295\u8cc7\u6210\u70ba\u767e\u842c\u5bcc\u7fc1\u7684\u6f5b\u529b\uff0c\u800c\u4e14\u9019\u6b21\u7121\u9700\u82b1\u8cbb40\u591a\u5e74\u7684\u6642\u9593\u3002\u50c5\u50c510\u5e74\u6642\u9593\uff0cCRISPR\/Cas9\u5c31\u5df2\u7d93\u5f9e\u4e00\u500b\u6982\u5ff5\u6210\u70ba\u5373\u5c07\u4e0a\u5e02\u7684\u7522\u54c1\u3002\u96d6\u8aaa\u751f\u7269\u79d1\u6280\u80a1\u7684\u718a\u5e02\u9084\u5728\u6301\u7e8c\uff0c\u4f46\u96a8\u8457NTLA-2001\u4e09\u671f\u8a66\u9a57\u7684\u555f\u52d5\uff0c\u9019\u53ea\u81e8\u5e8a\u968e\u6bb5\u7684\u751f\u7269\u79d1\u6280\u80a1\u7968\u503c\u5f97\u4e00\u640f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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