{"id":487261,"date":"2024-02-12T22:38:33","date_gmt":"2024-02-13T06:38:33","guid":{"rendered":"https:\/\/nai500.com\/blog\/2024\/02\/%e8%83%86%e5%a4%a7%e7%9a%84%e5%8f%af%e4%bb%a5%e8%80%83%e8%99%91%e8%bf%99%e4%b8%a4%e5%8f%aa%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e8%82%a1%e7%a5%a8\/"},"modified":"2024-02-12T22:38:47","modified_gmt":"2024-02-13T06:38:47","slug":"%e8%a1%8c%e6%83%85%e5%9b%9e%e6%9a%96-%e5%85%a9%e9%9a%bb-%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e8%82%a1%e7%a5%a8","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2024\/02\/%e8%a1%8c%e6%83%85%e5%9b%9e%e6%9a%96-%e5%85%a9%e9%9a%bb-%e5%9f%ba%e5%9b%a0%e7%b7%a8%e8%bc%af%e8%82%a1%e7%a5%a8\/","title":{"rendered":"\u884c\u60c5\u56de\u6696\uff0c\u81bd\u5927\u7684\u53ef\u4ee5\u8003\u616e\u9019\u5169\u96bb\u57fa\u56e0\u7de8\u8f2f\u80a1\u7968"},"content":{"rendered":"<p>\u751f\u7269\u79d1\u6280\u80a1\u7968\uff0c\u5c24\u5176\u662f\u90a3\u4e9b\u9084\u6c92\u6709\u7522\u54c1\u4e0a\u5e02\u548c\u6536\u5165\u7684\u80a1\u7968\u5c6c\u4e8e\u9ad8\u98a8\u96aa\u6295\u8cc7\u3002\u4e0d\u904e\uff0c\u5728\u7d93\u6b77\u6700\u8fd1\u718a\u5e02\uff0c\u4f30\u503c\u5927\u5e45\u4e0b\u79fb\u7684\u751f\u7269\u79d1\u6280\u80a1\u7968\u7684\u98a8\u96aa\u5df2\u7d93\u5927\u5927\u964d\u4f4e\u3002\u96d6\u7136\u65b0\u7684\u725b\u5e02\u5c0d\u751f\u7269\u79d1\u6280\u516c\u53f8\u7684\u6536\u5165\u6216\u81e8\u5e8a\u8a66\u9a57\u6c92\u6709\u4ec0\u9ebc\u5be6\u8cea\u4e0a\u7684\u5e6b\u52a9\uff0c\u4f46\u537b\u662f\u6295\u8cc7\u7372\u5229\u7684\u597d\u6642\u6a5f\u3002\u5982\u679c\u518d\u9047\u4e0a\u4ec0\u9ebc\u5229\u597d\uff0c\u80a1\u50f9\u4e0a\u6f32\u6f5b\u529b\u5c07\u88ab\u9032\u4e00\u6b65\u653e\u5927\u3002<\/p>\n<p>\u5e02\u5834\u884c\u60c5\u6b63\u5728\u56de\u6696\u4e26\u5e36\u52d5\u751f\u7269\u79d1\u6280\u80a1\u7968\u518d\u6b21\u4e0a\u6f32\u3002\u5982\u679c\u4f60\u81bd\u5b50\u5927\uff0c\u53ef\u4ee5\u8003\u616e\u4e0b\u9762\u9019\u5169\u96bb\u57fa\u56e0\u7de8\u8f2f\u80a1\u7968\u3002<\/p>\n<h2>1. Caribou Biosciences<\/h2>\n<p><a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=CRBU\">Caribou Biosciences Inc.\uff08NASDAQ:CRBU\uff09<\/a>\u4f9d\u7136\u8655\u65bc\u516c\u53f8\u767c\u5c55\u7684\u65e9\u671f\u968e\u6bb5\uff0c\u800c\u4e14\u53ea\u67093\u500b\u5747\u8655\u65bc\u4e00\u671f\u7684\u81e8\u5e8a\u968e\u6bb5\u7684\u958b\u767c\u9805\u76ee\u3002\u4e0d\u904e\uff0c\u8a72\u516c\u53f8\u7684\u57fa\u56e0\u7de8\u8f2f\u7d30\u80de\u7642\u6cd5CB-010\u2014\u2014\u9069\u61c9\u75c7\u70ba\u5fa9\u767c\u6027\u6216\u96e3\u6cbb\u6027B\u7d30\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08R\/R B-NHL\uff09\u2014\u2014\u662f\u9019\u53ea\u751f\u7269\u79d1\u6280\u80a1\u7968\u7684\u6700\u5927\u8ce3\u9ede\u3002<\/p>\n<p>CB-010\u5df2\u7d93\u7372\u5f97\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7ba1\u5c40\uff08FDA\uff09\u6388\u4e88\u7684\u518d\u751f\u91ab\u5b78\u5148\u9032\u7642\u6cd5\uff08RMAT\uff09\u3001\u5feb\u901f\u901a\u9053\u4ee5\u53ca\u5b64\u5152\u85e5\u8cc7\u683c\u8a8d\u5b9a\u3002\u6b64\u5916\uff0c\u53bb\u5e747\u6708\u767c\u4f48\u7684\u4e00\u671f\u81e8\u5e8a\u8a66\u9a57\u521d\u6b65\u7d50\u679c\u986f\u793a\uff0c\u8a72\u5019\u9078\u7642\u6cd5\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u90fd\u5f88\u4e0d\u932f\uff0c44%\u7684\u60a3\u8005\u9054\u5230\u5b8c\u5168\u7de9\u89e3\u4e26\u6301\u7e8c\u8d85\u904e6\u500b\u6708\u3002\u6700\u5f8c\uff0cFDA\u5df2\u7d93\u5728\u8a55\u4f30Caribou\u7684CB-010\u4e09\u671f\u8a66\u9a57\u8a08\u5283\uff0c\u9019\u4e5f\u5f9e\u5074\u9762\u53cd\u6620\u51fa\u76e3\u7ba1\u6a5f\u69cb\u5c0d\u65bc\u9019\u4e00\u7642\u6cd5\u5b89\u5168\u6027\u7684\u9ad8\u5ea6\u8a8d\u53ef\u3002\u8a66\u9a57\u9810\u8a08\u5c07\u57282024\u5e74\u5e95\u4e4b\u524d\u555f\u52d5\u3002<\/p>\n<p>\u8ca1\u52d9\u65b9\u9762\u3002Caribou Biosciences\u7684\u8cc7\u91d1\u80fd\u5920\u652f\u6301CB-010\u81f3\u5c11\u672a\u4f86\u5169\u5e74\u7684\u7e7c\u7e8c\u958b\u767c\u3002\u516c\u53f8\u904e\u53bb12\u500b\u6708\u7684\u71df\u696d\u8cbb\u7528\u90541.44\u5104\u7f8e\u5143\uff0c\u4f46\u622a\u81f32023\u5e74\u4e09\u5b63\u5ea6\u7684\u73fe\u91d1\u3001\u73fe\u91d1\u7b49\u50f9\u7269\u4ee5\u53ca\u77ed\u671f\u6295\u8cc7\u90543.38\u5104\u7f8e\u5143\u3002\u9019\u610f\u5473\u8457\u9019\u5bb6\u751f\u7269\u79d1\u6280\u516c\u53f8\u77ed\u671f\u4e4b\u5167\u6c92\u6709\u878d\u8cc7\u7684\u9700\u6c42\u3002<\/p>\n<h2>2. Verve Therapeutics<\/h2>\n<p>\u4e0d\u540c\u65bcCaribou\uff0cVerve Therapeutics Inc\uff08NASDAQ:VERV\uff09\u5c07\u81ea\u5df1\u57fa\u56e0\u7de8\u8f2f\u7684\u7814\u767c\u76ee\u6a19\u7784\u6e96\u4e86\u8af8\u5982\u96dc\u5408\u5b50\u5bb6\u65cf\u6027\u9ad8\u81bd\u56fa\u9187\u8840\u75c7\uff08HeFH\uff09\u7b49\u907a\u50b3\u75c5\uff0c\u4e26\u4e14\u91dd\u5c0d\u9019\u4e00\u75be\u75c5\u7684\u7814\u767c\u9805\u76eeVerve-101\u6b63\u8655\u65bc1b\u671f\u8a66\u9a57\u968e\u6bb5\u3002\u8a66\u9a57\u7684\u521d\u6b65\u6578\u64da\u975e\u5e38\u6a02\u89c0\uff0c\u60a3\u8005\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u81bd\u56fa\u9187\u4e0b\u964d\u5e45\u5ea6\u6700\u9ad8\u905455%\u3002<\/p>\n<p>\u672a\u4f8612\u500b\u6708\uff0cVerve\u6709\u591a\u500b\u6f5b\u5728\u7684\u50ac\u5316\u5291\u503c\u5f97\u671f\u5f85\u3002\u4eca\u5e74\u5e74\u521d\uff0cVerve-101\u7684\u5e73\u884c\u9805\u76eeVerve-102\u7684\u4e00\u671f\u8a66\u9a57\u555f\u52d5\u3002\u52302025\u5e74\uff0c\u516c\u53f8\u5c07\u5c0d\u9019\u5169\u500b\u7814\u767c\u9805\u76ee\u9032\u884c\u8003\u5bdf\u4e26\u6c7a\u5b9a\u7e7c\u7e8c\u63a8\u52d5\u54ea\u500b\u9805\u76ee\u3002\u800c\u4e14\u9577\u671f\u4f86\u770b\uff0c\u985e\u4f3cVerve-101\u548cVerve-102\u9019\u6a23\u7684\u9805\u76ee\u9084\u5177\u5099\u6cbb\u7642\u5176\u4ed6\u985e\u578b\u52d5\u8108\u7ca5\u6a23\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u75c5\uff08ASCVD\uff09\u7684\u6f5b\u529b\u3002<\/p>\n<p>\u8ca1\u52d9\u65b9\u9762\u3002Verve\u7684\u73fe\u91d1\u3001\u73fe\u91d1\u7b49\u50f9\u7269\u4ee5\u53ca\u77ed\u671f\u6295\u8cc7\u8d85\u904e6\u5104\u7f8e\u5143\uff0c\u7ba1\u7406\u5c64\u7a31\u9019\u4e9b\u8cc7\u91d1\u8db3\u5920\u652f\u6490\u516c\u53f8\u904b\u71df\u52302026\u5e74\u3002\u904e\u53bb12\u6708\uff0c\u8a72\u516c\u53f8\u7684\u73fe\u91d1\u6d88\u8017\u91cf\u70ba1.54\u5104\u7f8e\u5143\uff0c\u77ed\u671f\u4e4b\u5167\u65b0\u80a1\u767c\u884c\u7a00\u91cb\u73fe\u6709\u80a1\u6771\u80a1\u6b0a\u7684\u6982\u7387\u4e0d\u5927\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u751f\u7269\u79d1\u6280\u80a1\u7968\uff0c\u5c24\u5176\u662f\u90a3\u4e9b\u9084\u6c92\u6709\u7522\u54c1\u4e0a\u5e02\u548c\u6536\u5165\u7684\u80a1\u7968\u5c6c\u4e8e\u9ad8\u98a8\u96aa\u6295\u8cc7\u3002\u4e0d\u904e\uff0c\u5728\u7d93\u6b77\u6700\u8fd1\u718a\u5e02\uff0c\u4f30\u503c\u5927\u5e45\u4e0b\u79fb\u7684\u751f\u7269\u79d1\u6280 [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":482884,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1522,431],"tags":[809,927,2233,564],"class_list":["post-487261","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1522","category-trends-strategies-zh-hant","tag-809","tag-927","tag-2233","tag-564","sectors-life-science-zh-hant","locations-us-zh-hant","exchange-nasdaq-zh-hant"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/487261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=487261"}],"version-history":[{"count":3,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/487261\/revisions"}],"predecessor-version":[{"id":487264,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/487261\/revisions\/487264"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/482884"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=487261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=487261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=487261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}