{"id":552604,"date":"2024-09-25T20:26:18","date_gmt":"2024-09-26T03:26:18","guid":{"rendered":"https:\/\/nai500.com\/blog\/2024\/09\/%e4%bb%8a%e5%b9%b4%e9%a3%99%e5%8d%87-%e4%b8%a4%e5%8f%aa-%e7%be%8e%e8%82%a1%e6%8a%97%e7%99%8c%e8%8d%af%e8%82%a1%e7%a5%a8-%e7%bb%a7%e7%bb%ad%e6%b6%a8\/"},"modified":"2024-09-25T20:26:56","modified_gmt":"2024-09-26T03:26:56","slug":"%e4%bb%8a%e5%b9%b4%e9%a3%86%e5%8d%87-%e5%85%a9%e9%9a%bb-%e7%be%8e%e8%82%a1%e6%8a%97%e7%99%8c%e8%97%a5%e8%82%a1%e7%a5%a8-%e7%b9%bc%e7%ba%8c%e6%bc%b2","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2024\/09\/%e4%bb%8a%e5%b9%b4%e9%a3%86%e5%8d%87-%e5%85%a9%e9%9a%bb-%e7%be%8e%e8%82%a1%e6%8a%97%e7%99%8c%e8%97%a5%e8%82%a1%e7%a5%a8-%e7%b9%bc%e7%ba%8c%e6%bc%b2\/","title":{"rendered":"\u4eca\u5e74\u98c6\u5347\u8d85700%\u9084\u4e0d\u5920\uff0c\u9019\u5169\u96bb\u7f8e\u80a1\u6297\u764c\u85e5\u80a1\u7968\u9084\u80fd\u7e7c\u7e8c\u6f32\uff01"},"content":{"rendered":"<p>\u4eca\u5e74\u7f8e\u80a1\u7684\u5927\u725b\u80a1\u7576\u4e2d\uff0c\u6295\u8cc7\u8005\u5011\u767c\u73fe\u4e86\u5169\u5bb6\u764c\u75c7\u85e5\u7269\u958b\u767c\u516c\u53f8\u3002\u5f9e2023\u5e74\u5e95\u52302024\u5e749\u670823\u65e5\u6536\u76e4\u70ba\u6b62\uff0c<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=SMMT\">Summit Therapeutics (SMMT) <\/a>\u548c Instil Bio (TIL)\u7684\u80a1\u50f9\u5747\u4e0a\u6f32\u8d85\u904e700%\u3002\u9019\u4e9b\u80a1\u7968\u4e4b\u6240\u4ee5\u8868\u73fe\u512a\u7570\uff0c\u662f\u56e0\u70ba\u5b83\u5011\u958b\u767c\u7684\u65b0\u85e5\u5019\u9078\u7522\u54c1\u53ef\u80fd\u6210\u70ba\u9019\u500b\u6642\u4ee3\u6700\u6210\u529f\u7684\u764c\u75c7\u6cbb\u7642\u624b\u6bb5\u4e4b\u4e00\uff0c\u5e74\u92b7\u552e\u984d\u6709\u671b\u9054\u5230\u6578\u5341\u5104\u7f8e\u5143\u3002<\/p>\n<p>\u53bb\u5e74\uff0c\u50c5\u9ed8\u514b\u516c\u53f8\u751f\u7522\u7684\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u85e5\u7269Keytruda\u5c31\u5be6\u73fe\u4e86250\u5104\u7f8e\u5143\u7684\u92b7\u552e\u984d\u3002\u6700\u8fd1\u7684\u81e8\u5e8a\u8a66\u9a57\u6578\u64da\u8868\u660e\uff0cSummit Therapeutics\u548cInstil Bio\u5404\u81ea\u6b63\u5728\u7814\u767c\u7684\u5019\u9078\u85e5\u7269\u524d\u666f\u53ef\u671f\u3002\u5982\u679c\u8a66\u9a57\u53d6\u5f97\u6210\u529f\uff0c\u9019\u5169\u96bb\u524d\u5546\u696d\u5316\u968e\u6bb5\u88fd\u85e5\u5546\u7684\u80a1\u50f9\u5c07\u6f32\u7834\u5929\u969b\u3002<\/p>\n<h2>1. Summit Therapeutics<\/h2>\n<p>Summit Therapeutics\u7684\u80a1\u50f9\u66fe\u4e00\u5ea6\u4e0a\u6f32\u8d85\u904e1000%\uff0c\u7136\u5f8c\u56de\u843d\u3002\u52309\u670823\u65e5\u6536\u76e4\u6642\uff0c\u8a72\u80a12024\u5e74\u7684\u6f32\u5e45\u4f9d\u7136\u9ad8\u9054739.5%\u3002Summit\u80a1\u50f9\u4e4b\u6240\u4ee5\u98c6\u5347\uff0c\u662f\u56e0\u70baAkeso\u6388\u6b0a\u7684\u80ba\u764c\u6cbb\u7642\u85e5\u7269ivonescimab\u5728\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u4e2d\u8868\u73fe\u512a\u65bcKeytruda\u3002<\/p>\n<p>\u5728\u4e2d\u570b\uff0cSummit\u7684\u5408\u4f5c\u5925\u4f34\u5eb7\u65b9\u751f\u7269\u76ee\u524d\u6b63\u5728\u9032\u884c\u540d\u70baHARMONi-2\u7684\u982d\u5c0d\u982d\u4e09\u671f\u8a66\u9a57\uff0c\u91dd\u5c0d\u65b0\u8a3a\u65b7\u7684\u80ba\u764c\u60a3\u8005\u3002\u4e2d\u671f\u5206\u6790\u986f\u793a\uff0c\u76f8\u6bd4Keytruda\uff0civonescimab\u6cbb\u7642\u60a3\u8005\u7684\u75be\u75c5\u60e1\u5316\u98a8\u96aa\u964d\u4f4e\u4e8649%\u3002\u53bb\u5e7410\u6708\uff0cSummit\u5728\u5317\u7f8e\u555f\u52d5\u4e86HARMONi-3\u8a66\u9a57\uff0c\u62db\u52df\u4e86400\u540d\u4e00\u7dda\u80ba\u764c\u60a3\u8005\u3002\u9019\u9805\u7814\u7a76\u5c07\u6bd4\u8f03\u5316\u7642+Keytruda\u8207\u5316\u7642+ivonescimab\u806f\u5408\u7642\u6cd5\u7684\u7642\u6548\u3002<\/p>\n<p>\u4e2d\u570b\u76e3\u7ba1\u6a5f\u69cb\u5df2\u65bc\u4e94\u6708\u6279\u51c6\u4e86ivonescimab\u8207\u5316\u7642\u806f\u5408\u4f7f\u7528\uff0c\u7528\u65bc\u4e8c\u7dda\u80ba\u764c\u60a3\u8005\u7684\u6cbb\u7642\u3002\u96d6\u7136Summit\u7684\u6388\u6b0a\u4e0d\u5305\u62ec\u5728\u4e2d\u570b\u6216\u6fb3\u5927\u5229\u4e9e\u7684\u92b7\u552e\uff0c\u4f46\u9019\u81f3\u5c11\u8868\u660e\u8a72\u85e5\u7269\u5df2\u7d93\u7372\u5f97\u4e86\u4e00\u500b\u653f\u5e9c\u76e3\u7ba1\u6a5f\u69cb\u7684\u8a8d\u53ef\u3002<\/p>\n<p>Summit\u4ee5\u80ba\u764c\u4f5c\u70ba\u7a81\u7834\u53e3\uff0c\u56e0\u70ba\u9019\u662f\u76ee\u524d\u6700\u81f4\u547d\u7684\u764c\u75c7\u4e4b\u4e00\uff0c\u4f46\u516c\u53f8\u4e26\u4e0d\u6b62\u6b65\u65bc\u6b64\u3002Summit\u6700\u8fd1\u5831\u544a\u7a31\uff0civonescimab\u5728\u7d50\u8178\u3001\u4e73\u817a\u3001\u982d\u9838\u7b49\u5be6\u9ad4\u816b\u7624\u4e2d\u986f\u793a\u51fa\u8f03\u597d\u7684\u7de9\u89e3\u7387\u3002<\/p>\n<h2>2. Instil Bio<\/h2>\n<p>Instil Bio\u662f\u53e6\u4e00\u5bb6\u5f9e\u4e2d\u570b\u5408\u4f5c\u5925\u4f34\u90a3\u88e1\u7372\u5f97\u96d9\u7279\u7570\u6027PD-1\/VEGF\u6297\u9ad4\u6388\u6b0a\u7684\u7f8e\u570b\u88fd\u85e5\u5546\u3002\u5b9c\u660e\u6602\u79d1\u6388\u6b0a\u7684\u85e5\u7269\u70baIMM2510\uff0cInstil\u66ab\u6642\u547d\u540d\u70baSYN-2510\u3002\u96d6\u7136\u6211\u5011\u6c92\u6709SYN-2510\u548cKeytruda\u7684\u5c0d\u6bd4\u6578\u64da\uff0c\u4f46\u4e0d\u59a8\u7919Instil Bio\u80a1\u50f9\u7684\u66b4\u6f32\u3002\u622a\u81f39\u670824\u65e5\u65e9\u76e4\uff0c\u9019\u5bb6\u81e8\u5e8a\u968e\u6bb5\u88fd\u85e5\u5546\u7684\u80a1\u50f9\u57282024\u5e74\u4e0a\u6f32\u4e86814%\u3002<\/p>\n<p>\u5728\u7814\u767c\u9032\u5ea6\u4e0a\uff0cSYN-2510\u8981\u9060\u9060\u843d\u5f8c\u65bcivonescimab\uff0c\u4f46Instil Bio\u548c\u5b9c\u660e\u6602\u79d1\u5df2\u5236\u5b9a\u4e86\u8ffd\u8d95\u8a08\u5283\u3002\u9019\u5bb6\u4e2d\u570b\u5408\u4f5c\u5925\u4f34\u6700\u8fd1\u5ba3\u4f48\u4e86\u5f8c\u671f\u958b\u767c\u7b56\u7565\uff0c\u5176\u4e2d\u5305\u62ec\u9810\u8a08\u4eca\u5e74\u665a\u4e9b\u6642\u5019\u5728\u4e2d\u570b\u555f\u52d5\u4e00\u7dda\u80ba\u764c\u8a66\u9a57\u3002\u6b64\u5916\uff0cInstil\u9810\u8a08\u4e5f\u5c07\u5728\u4eca\u5e74\u5728\u7f8e\u570b\u555f\u52d5SYN-2510\u4f5c\u70ba\u4e8c\u7dda\u80ba\u764c\u6cbb\u7642\u7684\u4e8c\u671f\u8a66\u9a57\u3002\u4f5c\u7528\u6a5f\u5236\u4e0a\uff0cSYN-2510\u4f5c\u7528\u65bc\u816b\u7624\u7d30\u80de\u4e0a\u7684PD-L1\uff0c\u800civonescimab\u5247\u9776\u5411\u514d\u75ab\u7d30\u80de\u4e0a\u7684PD-1\u3002\u6b64\u5916\uff0cSYN-2510\u7d50\u5408\u591a\u7a2eVEGF\u914d\u9ad4\uff0c\u4e0d\u50c5\u9650\u65bcivonescimab\u7684VEGF-A\u3002<\/p>\n<h2>Summit Therapeutics\u9084\u662fInstil Bio\uff1f<\/h2>\n<p>\u96d6\u7136ivonescimab\u6709\u53ef\u80fd\u6210\u70ba\u9818\u5148\u7684\u80ba\u764c\u6cbb\u7642\u85e5\u7269\uff0c\u4f46Summit Therapeutics\u7684\u5e02\u503c\u4e5f\u5df2\u589e\u81f3\u7d04159\u5104\u7f8e\u5143\u3002\u5c0d\u65bc\u4e00\u5bb6\u5c1a\u7121\u7522\u54c1\u53ef\u8ce3\u7684\u516c\u53f8\u4f86\u8aaa\uff0c\u4f30\u503c\u98a8\u96aa\u4e0d\u4f4e\uff0c\u4efb\u4f55\u8ca0\u9762\u7684\u81e8\u5e8a\u8a66\u9a57\u6578\u64da\u90fd\u53ef\u80fd\u5c0d\u8a72\u80a1\u9020\u6210\u6253\u64ca\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0cInstil Bio\u5e02\u503c\u53ea\u67094.51\u5104\u7f8e\u5143\u3002\u4e0d\u904e\uff0c\u7531\u65bc\u6709\u95dc\u8a72\u516c\u53f8\u96d9\u7279\u7570\u6027\u6297\u9ad4SYN-2510\u7684\u4fe1\u606f\u6709\u9650\uff0c\u9019\u7576\u4e2d\u4e5f\u860a\u85cf\u8457\u98a8\u96aa\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4eca\u5e74\u7f8e\u80a1\u7684\u5927\u725b\u80a1\u7576\u4e2d\uff0c\u6295\u8cc7\u8005\u5011\u767c\u73fe\u4e86\u5169\u5bb6\u764c\u75c7\u85e5\u7269\u958b\u767c\u516c\u53f8\u3002\u5f9e2023\u5e74\u5e95\u52302024\u5e749\u670823\u65e5\u6536\u76e4\u70ba\u6b62\uff0cSum [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":552602,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1522,431],"tags":[801,2156,927,564],"class_list":["post-552604","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1522","category-trends-strategies-zh-hant","tag-801","tag-2156","tag-927","tag-564","sectors-life-science-zh-hant","locations-china-zh-hant","locations-us-zh-hant","exchange-nasdaq-zh-hant"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/552604","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=552604"}],"version-history":[{"count":3,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/552604\/revisions"}],"predecessor-version":[{"id":552608,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/552604\/revisions\/552608"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/552602"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=552604"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=552604"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=552604"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}