{"id":553229,"date":"2024-10-02T00:22:54","date_gmt":"2024-10-02T07:22:54","guid":{"rendered":"https:\/\/nai500.com\/blog\/2024\/10\/%e7%99%be%e6%97%b6%e7%be%8e%e6%96%bd%e8%b4%b5%e5%ae%9d%e6%94%af%e4%bb%98-1-1-%e4%ba%bf%e7%be%8e%e5%85%83%e8%be%be%e6%88%90-t-%e7%bb%86%e8%83%9e%e7%96%97%e6%b3%95%e5%8d%8f%e8%ae%ae\/"},"modified":"2024-10-02T00:23:33","modified_gmt":"2024-10-02T07:23:33","slug":"%e7%99%be%e6%99%82%e7%be%8e%e6%96%bd%e8%b2%b4%e5%af%b6%e6%94%af%e4%bb%98-1-1-%e5%84%84%e7%be%8e%e5%85%83%e9%81%94%e6%88%90-t-%e7%b4%b0%e8%83%9e%e7%99%82%e6%b3%95%e5%8d%94%e8%ad%b0","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2024\/10\/%e7%99%be%e6%99%82%e7%be%8e%e6%96%bd%e8%b2%b4%e5%af%b6%e6%94%af%e4%bb%98-1-1-%e5%84%84%e7%be%8e%e5%85%83%e9%81%94%e6%88%90-t-%e7%b4%b0%e8%83%9e%e7%99%82%e6%b3%95%e5%8d%94%e8%ad%b0\/","title":{"rendered":"\u767e\u6642\u7f8e\u65bd\u8cb4\u5bf6\u652f\u4ed81.1\u5104\u7f8e\u5143\u9054\u6210T\u7d30\u80de\u7642\u6cd5\u5354\u8b70"},"content":{"rendered":"<p class=\"p1\">\u6700\u8fd1\uff0c\u91ab\u85e5\u4f01\u696dPrime Medicine \u5411\u6295\u8cc7\u8005\u767c\u51fa\u8b66\u544a\uff0c\u5c0d\u8a72\u516c\u53f8\u662f\u5426\u6709\u80fd\u529b\u7dad\u6301 12 \u500b\u6708\u7684\u904b\u71df\u503c\u5f97\u61f7\u7591\u3002\u9031\u4e00\u5ba3\u4f48\u7684\u5169\u7b46\u4ea4\u6613\u61c9\u6709\u52a9\u65bc\u7de9\u89e3\u7576\u524d\u7684\u73fe\u91d1\u554f\u984c\u3002<a href=\"https:\/\/nai500.com\/zh-hant\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%a9%a2\/?qm_symbol=BMS\">\u767e\u6642\u7f8e\u65bd\u8cb4\u5bf6\uff08BMS\uff09<\/a>\u5c07\u5411 Prime Medicine \u652f\u4ed8 1.1 \u5104\u7f8e\u5143\u7684\u9810\u4ed8\u6b3e\uff0c\u7528\u65bc\u958b\u767c\u9ad4\u5916 T \u7d30\u80de\u7642\u6cd5\u8a66\u5291\u3002Prime \u5c07\u7372\u5f97\u9ad8\u9054 35 \u5104\u7f8e\u5143\u7684\u91cc\u7a0b\u7891\u6536\u76ca\uff0c\u8a72\u516c\u53f8\u5728\u62ab\u9732\u9019\u7b46\u4ea4\u6613\u7684\u540c\u6642\uff0c\u9084\u62ab\u9732\u4e86\u65e8\u5728\u5c07\u5176\u73fe\u91d1\u6d41\u5ef6\u9577\u81f3 2026 \u5e74\u4e0a\u534a\u5e74\u7684\u7ba1\u7dda\u512a\u5148\u6392\u5e8f\u7d30\u7bc0\u3002<\/p>\n<p class=\"p1\">BMS \u5c07\u8207 Prime \u5408\u4f5c\uff0c\u9032\u4e00\u6b65\u6316\u6398\u7d30\u80de\u7642\u6cd5\u5728\u514d\u75ab\u5b78\u548c\u816b\u7624\u5b78\u9818\u57df\u7684\u6f5b\u529b\u3002\u4f5c\u70ba\u5c0d\u73fe\u91d1\u652f\u4ed8\u548c\u80a1\u6b0a\u6295\u8cc7\u5e73\u5206\u7684\u9810\u4ed8\u6b3e\u7684\u56de\u5831\uff0cPrime \u5c07\u91dd\u5c0d\u9078\u5b9a\u7684\u76ee\u6a19\u8a2d\u8a08\u512a\u5316\u7684 Prime Editor \u8a66\u5291\u3002\u8a72\u9805\u76ee\u5305\u62ec\u4f7f\u7528PASSIGE\u6280\u8853\u7684\u8a66\u5291\u3002<\/p>\n<p class=\"p1\">Prime \u9996\u5e2d\u57f7\u884c\u5b98Keith Gottesdiener\u672c\u6708\u65e9\u4e9b\u6642\u5019\u5728\u6469\u6839\u58eb\u4e39\u5229\u7684\u4e00\u6b21\u6d3b\u52d5\u4e2d\u8a0e\u8ad6\u4e86 PASSIGE \u7684\u5438\u5f15\u529b\u3002 PASSIGE\u53ef\u4ee5\u9032\u5165\u57fa\u56e0\u7d44\u4e26\u9032\u884c\u7cbe\u78ba\u7684\u6cbb\u7642\u6027\u4fee\u6b63\uff0c\u800c\u4e0d\u9700\u8981\u5728\u57fa\u56e0\u7d44\u7684\u5176\u4ed6\u5730\u65b9\u4e82\u52d5\uff0c\u9019\u5c0d\u91ab\u751f\u548c\u75c5\u4eba\u4f86\u8aaa\u90fd\u975e\u5e38\u91cd\u8981\uff0c\u53ef\u80fd\u5c0d\u76e3\u7ba1\u6a5f\u69cb\u63a5\u53d7\u57fa\u56e0\u7de8\u8f2f\u65b9\u6cd5\u4e5f\u975e\u5e38\u91cd\u8981\u3002<\/p>\n<p class=\"p1\">BMS\u7684\u4ea4\u6613\u5305\u62ec14\u5104\u7f8e\u5143\u7684\u958b\u767c\u91cc\u7a0b\u7891\uff0c\u662f\u7de9\u89e3Prime\u73fe\u91d1\u64d4\u6182\u7684\u5169\u4ef6\u4e8b\u4e4b\u4e00\u3002Prime \u516c\u53f8\u6700\u8fd1\u66fe\u8b66\u544a\u6295\u8cc7\u8005\uff0c\u6301\u7e8c 12 \u500b\u6708\u7684\u7d93\u71df\u80fd\u529b\u4ee4\u4eba\u56b4\u91cd\u61f7\u7591\u3002\u9664\u4e86\u901a\u904e BMS \u4ea4\u6613\u5f15\u5165\u73fe\u91d1\u5916\uff0cPrime \u9084\u5728\u63a1\u53d6\u63aa\u65bd\u6e1b\u7de9\u8cc7\u91d1\u7684\u6d41\u51fa\u901f\u5ea6\u3002<\/p>\n<p class=\"p1\">\u5728\u8840\u6db2\u5b78\u3001\u514d\u75ab\u5b78\u548c\u816b\u7624\u5b78\u9818\u57df\uff0cPrime\u6b63\u5c08\u6ce8\u65bc\u5169\u500b\u9ad4\u5916\u81ea\u9ad4\u9020\u8840\u4e7e\u7d30\u80de\u9805\u76ee\uff0c\u7528\u65bc\u6cbb\u7642\u4e0d\u540c\u5f62\u5f0f\u7684\u6162\u6027\u8089\u82bd\u816b\u75c5\u3002\u6700\u5148\u9032\u8cc7\u7522\u7684\u521d\u6b65\u81e8\u5e8a\u6578\u64da\u5c07\u65bc2025\u5e74\u516c\u4f48\u3002Prime\u516c\u53f8\u5df2\u5c07\u5a01\u723e\u905c\u6c0f\u75c5\u9805\u76ee\u78ba\u5b9a\u70ba\u809d\u75c5\u5de5\u4f5c\u7684\u91cd\u9ede\uff0c\u8a72\u9805\u76ee\u53ef\u80fd\u65bc2026\u5e74\u9032\u5165\u81e8\u5e8a\u3002\u56ca\u6027\u7e96\u7dad\u5316\u57fa\u91d1\u6703\uff08Cystic Fibrosis Foundation\uff09\u7684\u8cc7\u52a9\u5c07\u4f7f Prime \u80fd\u5920\u7e7c\u7e8c\u958b\u5c55\u56ca\u6027\u7e96\u7dad\u5316\u65b9\u9762\u7684\u5de5\u4f5c\u3002<\/p>\n<p class=\"p2\">\u9664\u6b64\u4e4b\u5916\uff0c\u8a72\u516c\u53f8\u9084\u5728\u5c0b\u627e\u5408\u4f5c\u5925\u4f34\u4f86\u63a8\u9032\u9805\u76ee\u3002<span class=\"s1\">Prime<\/span>\u516c\u53f8\u7684\u7522\u54c1\u7dda\u5305\u62ec\u7cd6\u539f\u8caf\u7a4d\u75c5<span class=\"s1\">1b<\/span>\u3001\u8996\u7db2\u819c\u8272\u7d20\u8b8a\u6027\u548c\u5f17\u91cc\u5fb7\u96f7\u5e0c\u5171\u6fdf\u5931\u8abf\u7b49\u5df2\u9054\u5230\u5148\u5c0e\u512a\u5316\u968e\u6bb5\u7684\u9805\u76ee\uff0c\u4ee5\u53ca\u5176\u4ed6\u9069\u61c9\u75c7\u7684\u767c\u73fe\u968e\u6bb5\u9805\u76ee\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6700\u8fd1\uff0c\u91ab\u85e5\u4f01\u696dPrime Medicine \u5411\u6295\u8cc7\u8005\u767c\u51fa\u8b66\u544a\uff0c\u5c0d\u8a72\u516c\u53f8\u662f\u5426\u6709\u80fd\u529b\u7dad\u6301 12 \u500b\u6708\u7684\u904b\u71df\u503c\u5f97\u61f7\u7591 [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":553227,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[426],"tags":[809,927,644,564],"class_list":["post-553229","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-market-news-zh-hant","tag-809","tag-927","tag-644","tag-564","sectors-life-science-zh-hant","locations-us-zh-hant","exchange-nasdaq-zh-hant","exchange-nyse-zh-hant"],"acf":[],"_links":{"self":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/553229","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=553229"}],"version-history":[{"count":3,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/553229\/revisions"}],"predecessor-version":[{"id":553232,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/posts\/553229\/revisions\/553232"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media\/553227"}],"wp:attachment":[{"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=553229"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=553229"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nai500.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=553229"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}