{"id":563449,"date":"2025-01-16T19:16:49","date_gmt":"2025-01-17T03:16:49","guid":{"rendered":"https:\/\/nai500.com\/blog\/2025\/01\/%e4%b8%a4%e5%8f%aa%e8%82%a1%e4%bb%b7%e6%8e%a5%e8%bf%9152%e5%91%a8%e4%bd%8e%e7%82%b9%e7%9a%84%e4%bc%98%e8%b4%a8%e5%8c%bb%e7%96%97%e8%82%a1\/"},"modified":"2025-01-16T19:17:30","modified_gmt":"2025-01-17T03:17:30","slug":"%e5%85%a9%e9%9a%bb%e8%82%a1%e5%83%b9%e6%8e%a5%e8%bf%9152%e5%91%a8%e4%bd%8e%e9%bb%9e%e7%9a%84%e5%84%aa%e8%b3%aa%e9%86%ab%e7%99%82%e8%82%a1","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2025\/01\/%e5%85%a9%e9%9a%bb%e8%82%a1%e5%83%b9%e6%8e%a5%e8%bf%9152%e5%91%a8%e4%bd%8e%e9%bb%9e%e7%9a%84%e5%84%aa%e8%b3%aa%e9%86%ab%e7%99%82%e8%82%a1\/","title":{"rendered":"\u6703\u8ce3\u7684\u4e0d\u5982\u6703\u8cb7\u7684\uff1a\u5169\u96bb\u80a1\u50f9\u63a5\u8fd152\u5468\u4f4e\u9ede\u7684\u512a\u8cea\u91ab\u7642\u80a1"},"content":{"rendered":"<p>\u4e00\u4e9b\u6295\u8cc7\u8005\u8a8d\u70ba\uff0c\u6295\u8cc7\u80a1\u7968\u8cfa\u9322\u767c\u751f\u5728\u8cb7\u5165\u80a1\u7968\u7684\u6642\u5019\uff0c\u800c\u975e\u8ce3\u51fa\u6642\u3002\u80cc\u5f8c\u7684\u908f\u8f2f\u662f\uff0c\u5728\u5408\u9069\u7684\u6642\u6a5f\u8cb7\u5165\u6b63\u78ba\u7684\u80a1\u7968\uff0c\u4e26\u6301\u6709\u4e00\u6bb5\u6642\u9593\uff0c\u9019\u662f\u6295\u8cc7\u8005\u7372\u5f97\u512a\u7570\u56de\u5831\u7684\u6700\u4f73\u7b56\u7565\u4e4b\u4e00\u3002\u56e0\u6b64\uff0c\u5982\u679c\u4e00\u96bb\u80a1\u7968\u7684\u50f9\u683c\u63a5\u8fd152\u5468\u4f4e\u9ede\uff0c\u5149\u9019\u4e00\u9ede\u4e26\u4e0d\u8db3\u4ee5\u69cb\u6210\u6295\u8cc7\u8005\u56de\u907f\u7684\u7406\u7531\u3002\u76f8\u53cd\uff0c\u53ea\u8981\u662f\u597d\u80a1\u7968\uff0c\u53cd\u800c\u662f\u6295\u8cc7\u7684\u6700\u4f73\u6642\u6a5f\u3002<\/p>\n<p>\u9452\u65bc\u6b64\uff0c\u6211\u5011\u4f86\u770b\u770b\u5169\u96bb\u8fd1\u671f\u8868\u73fe\u4e0d\u4f73\uff0c\u76ee\u524d\u80a1\u50f9\u63a5\u8fd152\u5468\u4f4e\u9ede\u4f46\u4ecd\u503c\u5f97\u6295\u8cc7\u7684\u7f8e\u80a1\u91ab\u7642\u80a1\u7968\uff1a<a href=\"https:\/\/nai500.com\/zh-hans\/%e8%82%a1%e7%a5%a8%e6%9f%a5%e8%af%a2\/?qm_symbol=CRSP\">CRISPR Therapeutics\uff08CRSP\uff09<\/a>\u548cAmgen\uff08AMGN\uff09\u3002<\/p>\n<h2>1. CRISPR Therapeutics<\/h2>\n<p>CRISPR Therapeutics\u662f\u4e00\u5bb6\u5c08\u6ce8\u4e8e\u57fa\u56e0\u7de8\u8f2f\u7684\u4e2d\u671f\u751f\u7269\u6280\u8853\u516c\u53f8\u3002\u76ee\u524d\uff0c\u8a72\u516c\u53f8\u53ea\u6709\u4e00\u500b\u7522\u54c1\u4e0a\u5e02\uff0c\u5373\u6cbb\u7642\u8f38\u8840\u4f9d\u8cf4\u578b\u03b2\u5730\u4e2d\u6d77\u8ca7\u8840\u548c\u942e\u72c0\u7d30\u80de\u75c5\u7684Casgevy\uff0c\u9019\u5169\u7a2e\u90fd\u662f\u7f55\u898b\u7684\u8840\u6db2\u75be\u75c5\u3002Casgevy\u4e0a\u5e02\u5df2\u4e00\u5e74\u591a\uff0c\u6210\u70ba\u9996\u500b\u4f7f\u7528\u8afe\u8c9d\u723e\u734e\u7372\u734eCRISPR\u6280\u8853\u7684\u57fa\u56e0\u7de8\u8f2f\u6cbb\u7642\uff0c\u9019\u662fCRISPR Therapeutics\u53d6\u5f97\u7684\u5353\u8d8a\u6210\u5c31\u3002<\/p>\n<p>\u8a71\u96d6\u5982\u6b64\uff0c\u4f46\u7531\u65bc\u57fa\u56e0\u7de8\u8f2f\u6cbb\u7642\u7684\u8907\u96dc\u6027\uff0c\u8a72\u7522\u54c1\u5c1a\u672a\u70ba\u516c\u53f8\u5e36\u4f86\u6536\u5165\u3002\u6b64\u5916\uff0c\u516c\u53f8\u4f9d\u7136\u8655\u65bc\u8667\u640d\u72c0\u614b\uff0c\u9019\u89e3\u91cb\u4e86\u8a72\u80a1\u70ba\u4f55\u5927\u5e45\u843d\u5f8c\u65bc\u5e02\u5834\u3002<\/p>\n<p>\u7136\u800c\uff0cCRISPR Therapeutics\u4f9d\u7136\u6709\u5f88\u591a\u53ef\u53d6\u4e4b\u8655\u3002<\/p>\n<ul>\n<li>\u9996\u5148\uff0c\u76ee\u524dCasgevy\u5728\u5e02\u5834\u4e0a\u5e7e\u4e4e\u627e\u4e0d\u5230\u7af6\u722d\u7522\u54c1\uff0c\u6f5b\u529b\u5de8\u5927\u3002\u8a72\u7642\u6cd5\u5728\u7f8e\u570b\u7684\u50f9\u683c\u70ba220\u842c\u7f8e\u5143\uff0c\u96a8\u8457\u7b2c\u4e09\u65b9\u4fdd\u96aa\u8986\u84cb\u7684\u63d0\u9ad8\uff0c\u758a\u52a0\u81f3\u5c1158,000\u4eba\u7684\u76ee\u6a19\u60a3\u8005\u7fa4\uff0c\u5dd4\u5cf0\u92b7\u552e\u984d\u61c9\u8a72\u9060\u9ad8\u65bc10\u5104\u7f8e\u5143\u3002<\/li>\n<li>\u5176\u6b21\uff0cCRISPR\u7684\u7814\u767c\u7ba1\u7dda\u5019\u9078\u85e5\u7269\u503c\u5f97\u671f\u5f85\u3002\u6700\u8fd1\uff0c\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6388\u4e88CRISPR\u516c\u53f8\u7684CTX112\u201c\u518d\u751f\u91ab\u5b78\u5148\u9032\u7642\u6cd5\uff08RMAT\uff09\u201d\u7684\u7a31\u865f\uff0c\u9019\u662f\u4e00\u7a2e\u91dd\u5c0d\u67d0\u4e9bB\u7d30\u80de\u60e1\u6027\u816b\u7624\u7684\u6f5b\u5728\u6cbb\u7642\u65b9\u6cd5\u3002<\/li>\n<\/ul>\n<p>\u5c0d\u65bc\u90a3\u4e9b\u80fd\u627f\u53d7\u98a8\u96aa\u7684\u6295\u8cc7\u8005\uff0c\u9019\u53ea\u80a1\u7968\u503c\u5f97\u6295\u8cc7\u3002<\/p>\n<h2>2. 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