{"id":594268,"date":"2025-09-22T06:26:44","date_gmt":"2025-09-22T13:26:44","guid":{"rendered":"https:\/\/nai500.com\/?p=594268"},"modified":"2025-09-22T06:26:44","modified_gmt":"2025-09-22T13:26:44","slug":"pfizer-pfe-49-cvr-metsera-mtsr","status":"publish","type":"post","link":"https:\/\/nai500.com\/zh-hant\/blog\/2025\/09\/pfizer-pfe-49-cvr-metsera-mtsr\/","title":{"rendered":"Pfizer (PFE) \u5c07\u4ee5 49 \u5104\u7f8e\u5143\u52a0 CVR \u6536\u8cfc Metsera (MTSR)"},"content":{"rendered":"

Pfizer \u5c07\u4ee5\u73fe\u91d1 49 \u5104\u7f8e\u5143\u6536\u8cfc Metsera\uff0c\u652f\u4ed8\u6bcf\u80a1 47.50 \u7f8e\u5143\uff0c\u4e26\u5c31\u81e8\u5e8a\u8207\u76e3\u7ba1\u91cc\u7a0b\u7891\u6700\u591a\u518d\u652f\u4ed8\u6bcf\u80a1 22.50 \u7f8e\u5143\u3002\u6b64\u4ea4\u6613\u8f03 Metsera \u4e0a\u4e00\u4ea4\u6613\u65e5\u6536\u76e4\u50f9\u6ea2\u50f9 43%\uff0c\u82e5\u6240\u6709\u91cc\u7a0b\u7891\u9054\u6210\uff0c\u5c07\u4f7f\u9019\u5bb6\u6297\u80a5\u80d6\u958b\u767c\u5546\u7684\u4f30\u503c\u9ad8\u9054 72 \u5104\u7f8e\u5143\u3002Metsera \u80a1\u50f9\u5728\u76e4\u524d\u98c6\u5347\u8fd1 60%\uff0c\u800c Pfizer \u4e0a\u6f32\u7d04 2%\uff0c\u986f\u793a\u6295\u8cc7\u4eba\u504f\u597d\u5df2\u4ed8\u8cbb\u53d6\u5f97\u7684\u7ba1\u7dda\uff0c\u800c\u975e\u5728 Pfizer \u81ea\u8eab\u6e1b\u91cd\u8a08\u756b\u505c\u64fa\u5f8c\u518d\u5ea6\u5f9e\u5167\u90e8\u91cd\u555f\u7814\u767c\u3002<\/p>\n

\u5e02\u5834\u53cd\u61c9<\/h3>\n

\u4ea4\u6613\u54e1\u53cd\u61c9\u8fc5\u901f\u3002Metsera \u56e0\u6a19\u984c\u6240\u793a\u7684\u6ea2\u50f9\u4ee5\u53ca\u82e5\u5176\u5c08\u6848\u9032\u5c55\u53ef\u7372\u984d\u5916\u4ed8\u6b3e\u7684\u660e\u78ba\u8def\u5f91\u800c\u98c6\u5347\u3002Pfizer \u7684\u65e9\u76e4\u6f32\u5e45\u96d6\u5c6c\u6eab\u548c\uff0c\u4f46\u5c0d\u65bc\u9019\u5bb6\u5728\u4eca\u5e74\u65e9\u4e9b\u6642\u5019\u56e0\u809d\u6bd2\u6027\u7591\u616e\u800c\u7d42\u6b62 danuglipron \u5f8c\u4e00\u76f4\u96e3\u4ee5\u8aaa\u670d\u6295\u8cc7\u4eba\u5176\u80a5\u80d6\u7b56\u7565\u53ef\u4fe1\u7684\u5de8\u578b\u4f01\u696d\u4f86\u8aaa\u4ecd\u5177\u610f\u7fa9\u3002\u5c0d\u6574\u9ad4 GLP-1 \u751f\u614b\u7cfb\u7684\u63a8\u8ad6\u5177\u652f\u6301\u6027\uff1a\u5e02\u5834\u4ecd\u9858\u610f\u70ba\u665a\u671f\u6311\u6230\u8005\u63d0\u4f9b\u8cc7\u91d1\uff0c\u5373\u4fbf\u50f9\u683c\u5e36\u6709\u6ea2\u50f9\uff0c\u53ea\u8981\u5291\u91cf\u8a2d\u5b9a\u6216\u5b89\u5168\u6027\u6b0a\u8861\u770b\u4f86\u5177\u5dee\u7570\u5316\u3002\u9810\u671f Lilly \u8207 Novo \u7dad\u6301\u7a69\u5b9a\uff1b\u5169\u8005\u4ecd\u662f\u7642\u6548\u7684\u53c3\u8003\u6a19\u7684\u3002\u4f46\u4eca\u65e5\u5e02\u5834\u5728\u734e\u52f5\u4e00\u500b\u5927\u578b\u8cb7\u5bb6\uff0c\u56e0\u5176\u679c\u65b7\u884c\u52d5\u53bb\u88dc\u4e0a\u6230\u7565\u7f3a\u53e3\u3002<\/p>\n

\u4ea4\u6613\u689d\u6b3e\u8207\u91cc\u7a0b\u7891<\/h3>\n

\u57fa\u790e\u50f9\u683c\u70ba\u6bcf\u80a1 47.50 \u7f8e\u5143\u73fe\u91d1\u3002\u53ef\u5f97\u7684\u6216\u6709\u6b0a\u5229\uff08CVR\uff09\u6700\u9ad8\u6bcf\u80a1 22.50 \u7f8e\u5143\uff0c\u53d6\u6c7a\u65bc Metsera \u662f\u5426\u9054\u6210\u65e2\u5b9a\u91cc\u7a0b\u7891\uff0c\u5305\u62ec\u9818\u5148\u7d44\u5408\u7642\u7a0b\u555f\u52d5\u7b2c 3 \u671f\u8a66\u9a57\u4ee5\u53ca\u95dc\u9375\u5019\u9078\u85e5\u6700\u7d42\u7372\u5f97 FDA \u6838\u51c6\u3002\u6b64\u7d50\u69cb\u5c07\u5be6\u8cea\u98a8\u96aa\u8f49\u56de\u8ce3\u65b9\uff0c\u540c\u6642\u8b93 Pfizer \u5728\u6a19\u50f9\u4e0a\u7dad\u6301 49 \u5104\u7f8e\u5143\u7684\u982d\u689d\u6578\u5b57\u3002\u9019\u662f\u719f\u6089\u7684\u751f\u6280\u4ea4\u6613\u6a21\u677f\uff1a\u82e5\u958b\u767c\u98a8\u96aa\u964d\u4f4e\u5247\u6a19\u50f9\u8f03\u9ad8\uff0c\u82e5\u4e0d\u7136\u5247\u9810\u4ed8\u6b3e\u8f03\u4f4e\u3002\u6b64\u67b6\u69cb\u4e5f\u8868\u660e\u5c0d\u8cc7\u7522\u9032\u5c55\u7684\u4fe1\u5fc3\uff0c\u540c\u6642\u5728 Pfizer \u8fd1\u671f\u4e00\u9023\u4e32\u6536\u8cfc\u5f8c\u8868\u73fe\u51fa\u8cc7\u672c\u90e8\u7f72\u7684\u7d00\u5f8b\u3002\u4ea4\u6613\u5b8c\u6210\u4ecd\u9808\u53d6\u5f97\u76e3\u7ba1\u6279\u51c6\u53ca\u6163\u5e38\u6210\u4ea4\u689d\u4ef6\u3002\u82e5\u91cc\u7a0b\u7891\u9054\u6210\uff0cMetsera \u80a1\u6771\u6bcf\u80a1\u5be6\u969b\u51fa\u812b\u50f9\u53ef\u9054 70 \u7f8e\u5143\uff0c\u9019\u4e00\u6c34\u6e96\u6697\u793a Pfizer \u8a8d\u70ba\u9019\u4e9b\u8cc7\u7522\u80fd\u5728\u5176\u5167\u90e8\u65b9\u6848\u5931\u5229\u4e4b\u8655\u7af6\u722d\u3002<\/p>\n

\u7b56\u7565\u8207\u7522\u54c1\u7dda<\/h3>\n

\u9019\u662f\u5f9e\u5167\u90e8\u5275\u65b0\u5411\u5916\u90e8\u4f75\u8cfc\u7684\u4e00\u6b21\u660e\u986f\u8f49\u5411\u3002Pfizer \u7684\u53e3\u670d GLP-1 danuglipron \u906d\u9047\u5b89\u5168\u6027\u963b\u529b\u4e26\u88ab\u7d42\u6b62\uff0c\u4f7f\u5176\u5728\u4e00\u500b\u8a31\u591a\u4eba\u9810\u671f\u5230 2030 \u5e74\u521d\u6bcf\u5e74\u92b7\u552e\u984d\u5c07\u8d85\u904e 1,000 \u5104\u7f8e\u5143\u7684\u985e\u5225\u4e2d\uff0c\u8def\u5f91\u8b8a\u5f97\u4e0d\u660e\u6717\u3002Metsera \u5e36\u4f86\u91dd\u5c0d\u7b2c\u4e00\u6ce2 GLP-1 \u51fa\u73fe\u7684\u75db\u9ede\u6240\u8a2d\u8a08\u7684\u5be6\u9a57\u6027\u6e1b\u91cd\u7642\u6cd5\uff1a\u5291\u91cf\u8ca0\u64d4\u3001\u4f9b\u61c9\u9650\u5236\u8207\u8010\u53d7\u6027\u554f\u984c\u3002Metsera \u7684\u4e00\u9805\u5c08\u6848\u662f\u4e00\u7a2e\u9577\u6548\u6ce8\u5c04\u5291\uff0c\u5291\u6b21\u983b\u7387\u53ef\u80fd\u4f4e\u65bc\u73fe\u4eca\u4e3b\u5c0e\u7684\u6bcf\u9031\u6ce8\u5c04\u3002\u8f03\u4f4e\u7684\u7d66\u85e5\u983b\u7387\u80fd\u6539\u5584\u4f9d\u5f9e\u6027\u3001\u6e1b\u5c11\u81e8\u5e8a\u63a5\u89f8\u9ede\uff0c\u4e26\u964d\u4f4e\u55ae\u4f4d\u60a3\u8005\u7684\u88fd\u9020\u58d3\u529b\uff0c\u9019\u5728\u7522\u80fd\u6210\u70ba\u74f6\u9838\u6642\u662f\u91cd\u8981\u512a\u52e2\u3002Metsera \u4ea6\u5728\u63a8\u9032\u65e8\u5728\u653e\u5927\u9ad4\u91cd\u6e1b\u8f15\u6548\u679c\u540c\u6642\u63a7\u5236\u8178\u80c3\u526f\u4f5c\u7528\u7684\u7d44\u5408\u7642\u6cd5\uff0c\u9019\u662f\u65b0\u9032\u8005\u5728\u771f\u5be6\u4e16\u754c\u9762\u81e8\u7684\u4e3b\u8981\u969c\u7919\u3002\u5982\u679c\u6578\u64da\u6210\u7acb\uff0cPfizer \u4e0d\u50c5\u7372\u5f97\u4e00\u689d\u7ba1\u7dda\uff0c\u9084\u5f97\u5230\u4e86\u53ef\u653e\u5927\u5316\u7684\u5dee\u7570\u5316\u7522\u54c1\u7279\u6027\u3002<\/p>\n

\u80a5\u80d6\u85e5\u7af6\u8cfd<\/h3>\n

Novo Nordisk \u8207 Eli Lilly \u4ee5 Wegovy\u3001Ozempic \u8207 Zepbound \u7acb\u4e0b\u7642\u6548\u8207\u5e02\u5834\u57f7\u884c\u7684\u6a19\u6e96\u3002\u5b83\u5011\u5efa\u7acb\u4e86\u5f37\u5927\u7684\u4f9b\u61c9\u93c8\u8207\u7d66\u4ed8\u8986\u84cb\uff0c\u96d6\u7136\u9019\u4e9b\u4ecd\u5728\u6301\u7e8c\u6539\u5584\u4e2d\u3002\u5927\u578b\u85e5\u5ee0\u5df2\u4ee5\u4ea4\u6613\u56de\u61c9\u3002Roche \u6536\u8cfc Carmot \u4ee5\u7372\u5176 GLP-1 \u7d44\u5408\uff1bLilly \u6536\u8cfc Versanis \u5f37\u5316\u9ad4\u7d44\u6210\u79d1\u5b78\uff1bAstraZeneca \u8207\u5176\u4ed6\u5ee0\u5546\u5247\u5f15\u9032\u4e2d\u671f\u8cc7\u7522\u3002Pfizer \u5728\u4e00\u6b21\u516c\u958b\u7684\u632b\u6557\u5f8c\uff0c\u9078\u64c7\u8cb7\u4e0b\u4e00\u500b\u5177\u6709\u53ef\u4fe1\u6a5f\u6703\u7684\u76ee\u6a19\uff0c\u800c\u975e\u5f9e\u96f6\u958b\u59cb\u3002\u7af6\u722d\u7b56\u7565\u5f88\u6e05\u695a\uff1a\u5728\u7d66\u85e5\u983b\u7387\u3001\u526f\u4f5c\u7528\u7279\u5fb5\u6216\u53e3\u670d\u905e\u9001\u4e0a\u5dee\u7570\u5316\uff0c\u7136\u5f8c\u653e\u5927\u88fd\u9020\u8207\u5e02\u5834\u9032\u5165\u3002\u983b\u7387\u53ef\u80fd\u662f\u6700\u53ef\u64cd\u4f5c\u7684\u5207\u5165\u9ede\u3002\u5982\u679c Metsera \u7684\u7642\u7a0b\u4ee5\u66f4\u5c11\u6ce8\u5c04\u9054\u6210\u76f8\u8fd1\u7684\u6e1b\u91cd\u6548\u679c\uff0c\u5247\u53ef\u80fd\u5728\u7dad\u6301\u7642\u7a0b\u4e2d\u7372\u5f97\u5e02\u5834\u4efd\u984d\uff0c\u5728\u90a3\u88e1\u4fbf\u5229\u6027\u8207\u4f9d\u5f9e\u6027\u6700\u91cd\u8981\uff0c\u5373\u4fbf\u6700\u9ad8\u7642\u6548\u4ecd\u5c6c\u65e2\u6709\u5ee0\u5546\u3002<\/p>\n

\u6574\u5408\u8207\u6642\u7a0b<\/h3>\n

\u57f7\u884c\u73fe\u5728\u8f49\u5411\u8a66\u9a57\u8a2d\u8a08\u3001\u76e3\u7ba1\u5c0d\u8a71\u8207\u88fd\u9020\u898f\u5283\u3002Pfizer \u7684\u958b\u767c\u8207\u76e3\u7ba1\u57fa\u790e\u5efa\u8a2d\u662f\u8cc7\u7522\u3002\u5b83\u53ef\u4ee5\u52a0\u901f\u8a66\u9a57\u5730\u9ede\u555f\u52d5\u3001\u6a19\u6e96\u5316\u7d42\u9ede\uff0c\u4e26\u70ba\u5168\u7403\u898f\u6a21\u7684\u7b2c 3 \u671f\u505a\u6e96\u5099\u3002\u5c31\u88fd\u9020\u800c\u8a00\uff0c\u9577\u6548\u5291\u578b\u901a\u5e38\u9700\u8981\u4e0d\u540c\u7684\u5145\u586b\u5b8c\u6210\uff08fill-finish\uff09\u7b56\u7565\u8207\u4f9b\u61c9\u898f\u5283\u3002Pfizer \u5728\u75ab\u82d7\u8207\u816b\u7624\u751f\u7269\u88fd\u5291\u65b9\u9762\u6709\u5145\u8db3\u7684\u7522\u80fd\u898f\u5283\u7d93\u9a57\uff0c\u4f46 GLP-1 \u751f\u7522\u6709\u5176\u81ea\u8eab\u9650\u5236\uff1b\u63d0\u524d\u6295\u8cc7\u4ee5\u907f\u514d Novo \u8207 Lilly \u65e9\u671f\u7684\u74f6\u9838\u5c07\u81f3\u95dc\u91cd\u8981\u3002\u95dc\u9375\u89c0\u5bdf\u9ede\u70ba\u9818\u5148\u65b9\u6848\u7b2c 3 \u671f\u7684\u555f\u52d5\uff0c\u4ee5\u53ca\u6b63\u5728\u9032\u884c\u7684\u4e2d\u671f\u8a66\u9a57\u4e4b\u9802\u7dda\u8b80\u6578\uff0c\u9019\u4e9b\u5c07\u6846\u5b9a\u8207\u6bcf\u9031 GLP-1 \u6a19\u6e96\u76f8\u6bd4\u7684\u5291\u91cf\u8207\u8010\u53d7\u6027\u3002\u5d4c\u5165\u5728 CVR \u7684\u91cc\u7a0b\u7891\u5b9a\u7fa9\uff0c\u61c9\u4f5c\u70ba\u9019\u4e9b\u50ac\u5316\u5291\u7684\u516c\u958b\u8def\u7dda\u5716\uff0c\u8b93\u6295\u8cc7\u4eba\u5c0d\u9a45\u52d5\u50f9\u503c\u8f49\u79fb\u7684\u9580\u6abb\u6709\u53ef\u898b\u6027\u3002<\/p>\n

\u4f30\u503c\u8207\u6295\u8cc7\u4eba\u89c0\u9ede<\/h3>\n

\u4ee5 49 \u5104\u7f8e\u5143\u524d\u4ed8\u6b3e\u3001\u542b\u91cc\u7a0b\u7891\u6700\u591a\u81f3 72 \u5104\u7f8e\u5143\u8a08\u7b97\uff0cPfizer \u70ba\u9078\u64c7\u6b0a\u652f\u4ed8\u4e86\u9ad8\u6602\u4ee3\u50f9\uff0c\u4f46\u9650\u5236\u4e86\u77ed\u671f\u73fe\u91d1\u71c3\u71d2\u3002\u4f5c\u70ba\u6bd4\u8f03\uff0c\u9019\u4f7f\u57fa\u790e\u4ea4\u6613\u898f\u6a21\u9ad8\u65bc\u6578\u5b97\u8fd1\u671f\u7684\u4e2d\u671f\u4ee3\u8b1d\u8ced\u6ce8\uff0c\u4e26\u8207\u8cb7\u5165\u9032\u5165\u6b64\u6700\u53d7\u8ffd\u6367\u6cbb\u7642\u9818\u57df\u7684\u53ef\u4fe1\u8def\u5f91\u6240\u9700\u6210\u672c\u76f8\u7576\u3002\u5e02\u5834\u53cd\u61c9\u986f\u793a\u6295\u8cc7\u4eba\u63a5\u53d7\u9019\u7a2e\u6b0a\u8861\uff1a\u5982\u679c\u79d1\u5b78\u53ef\u884c\uff0c\u672a\u4f86\u591a\u4ed8\u4e9b\u6bd4\u4eca\u5929\u904e\u5ea6\u4ed8\u51fa\u4e26\u627f\u64d4\u5168\u90e8\u98a8\u96aa\u66f4\u597d\u3002\u5c0d Pfizer \u800c\u8a00\uff0c\u6578\u5b78\u53ea\u6709\u5728 Metsera \u80fd\u4ea4\u51fa\u7b2c 3 \u671f\u6c34\u6e96\u6578\u64da\u2500\u2500\u5728\u4fbf\u5229\u6027\u4e0a\u5c6c\u65bc\u540c\u7d1a\u6700\u4f73\u6216\u5728\u7642\u6548\u4e0a\u65bc\u66f4\u4f73\u8010\u53d7\u6027\u4e0b\u5177\u6709\u7af6\u722d\u529b\u2500\u2500\u6642\u624d\u6210\u7acb\u3002\u82e5\u9054\u6210\uff0cPfizer \u5c07\u7372\u5f97\u4e00\u9053\u53ef\u6301\u7e8c\u7684\u6210\u9577\u52d5\u80fd\uff0c\u4ee5\u5c0d\u6297 COVID \u9700\u6c42\u6b63\u5e38\u5316\u8207\u816b\u7624\u85e5\u5c08\u5229\u61f8\u5d16\u3002\u82e5\u672a\u9054\u6210\uff0cCVR \u5c07\u9650\u5b9a\u640d\u5931\u3002\u7121\u8ad6\u5982\u4f55\uff0c\u9019\u4e00\u8209\u52d5\u6709\u52a9\u65bc\u91d0\u6e05\u6230\u7565\uff0c\u800c\u9019\u4e00\u76f4\u662f\u6b20\u7f3a\u7684\u3002<\/p>\n

\u7d66\u4ed8\u8005\u52d5\u614b\u8207\u7372\u5229\u80fd\u529b<\/h3>\n

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