Investment Guide to Genetics Stocks and ETFs

This Cathie Wood-Favored Gene-Editing Stock Is Up 47% This Year. Is It Poised to Take Off?
Published on: Aug 28, 2025

The genetics investment landscape—encompassing four key segments: DNA sequencing, genetic testing, gene therapy, and genomics (including gene editing)—has garnered significant market attention in recent years.

Advances in gene sequencing technology have driven costs down at a pace exceeding Moore’s Law, making sequencing services increasingly accessible. Meanwhile, applications of genetic technology are expanding from hereditary disease screening to broader fields including precision oncology, cardiovascular risk prediction, personalized medication guidance, and rare disease treatment. In particular, gene and cell therapies offer new hope for previously incurable conditions.

CRISPR gene-editing technology is reshaping the industry, with a robust pipeline of late-stage clinical trials in gene therapy. The only CRISPR-based drug currently approved by the FDA is Casgevy, co-developed by Vertex Pharmaceuticals (NASDAQ:VRTX) and CRISPR Therapeutics (NASDAQ:CRSP). Tim Hunt, CEO of the Alliance for Regenerative Medicine, predicts that up to 10 cell and gene therapies could achieve blockbuster status by 2030.

Notably, artificial intelligence (AI) is emerging as a core driver of innovation in the genetics sector, significantly enhancing the efficiency of data processing, interpretation, and application. AI algorithms are accelerating target discovery and drug development processes while improving the precision of gene-editing tools such as CRISPR, effectively reducing off-target risks. This convergence of technologies is propelling the genetics industry from research to clinical application, profoundly reshaping the future of personalized medicine.

For investors interested in entering the genetics field, direct investment in gene stocks is a common approach. Another lower-risk option is investing in exchange-traded funds (ETFs), which provide exposure to a basket of stocks and help diversify risk.

Gene Stocks

Investors have multiple options—from large-cap biotech firms to pure-play companies focused on gene therapy, editing, and testing. Below are key companies in the genetics sector:

  • Large-Cap Gene Stock: Amgen (NASDAQ:AMGN)
    A global biotechnology leader, Amgen uses advanced human genetics to develop and manufacture therapeutics addressing diseases with high unmet medical needs. Its subsidiary deCODE Genetics researches how human genetic diversity influences disease.
  • Genetic Testing Stock: Illumina (NASDAQ:ILMN)
    Illumina develops, manufactures, and markets life science tools and integrated systems that enable genomic solutions for healthcare. Its focus areas include oncology testing, genetic disease testing, reproductive health, and research.
  • Gene Editing (CRISPR) Stock: CRISPR Therapeutics (NASDAQ:CRSP)
    CRISPR Therapeutics, in partnership with Vertex Pharmaceuticals, developed Casgevy—a CRISPR/Cas9-based genome-edited cell therapy. It is the first CRISPR treatment approved by the FDA, European Medicines Agency, and Health Canada.
  • Gene Therapy Stock: uniQure (NASDAQ:QURE)
    This genomic medicine company focuses on developing and commercializing gene therapies for patients with severe genetic diseases. Its AAV-based platform targets liver-directed and central nervous system disorders.

Genomics ETFs

For those seeking broad exposure to the genetics industry rather than individual stocks, ETFs offer a diversified one-click investment strategy. Notable genetics-themed ETFs include:

  • ARK Genomic Revolution ETF (ARCA:ARKG)
  • Invesco Dynamic Biotechnology & Genome ETF (PBE)
  • Global X Genomics & Biotechnology ETF (NASDAQ:GNOM)
  • iShares Genomics Immunology and Healthcare ETF (ARCA:IDNA)

These ETFs provide access to multiple segments of the genetics market, mitigating single-stock risk while capitalizing on industry growth.

AI Biotechnology Funds Genomics