Xynomic to Start US Trial Combining its Abexinostat with Janssen’s Imbruvica

Published on: Dec 5, 2017
Author: Amy Liu

Xynomic Pharma, a China-US oncology pharma, will start a Phase I/II trial of its lead candidate, the novel HDAC inhibitor Abexinostat, in combination with Janssen Pharma’s Imbruvica® (ibrutinib). Imbruvica is a first-in-class BTK inhibitor that quickly acquired blockbuster sales in several hard-to-treat cancer types. The trial will be conducted at New York City’s Memorial Sloan Kettering Cancer Center in patients with diffuse large B-cell lymphoma (DLBCL) and mantle cell lymphoma (MCL).

Source: China Biotoday

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