AstraZeneca’s Tagrisso Approved in China as First-Line Lung Cancer Treatment

AstraZeneca Tagrisso (osimertinib) China
Published on: Sep 5, 2019

AstraZeneca announced China approval for Tagrisso (osimertinib) as a first-line treatment for non-small cell lung cancer (NSCLC) in patients with EGFR exon 19 deletions or exon 21 (L858R) substitutions. In a Phase III trial, Tagrisso increased progression-free survival to 18.9 months, an improvement over 10.2 months for standard EGFR drugs. About 30%-40% of China NSCLC patients have EGFR mutations, an unusually high number. Previously, Tagrisso was approved in China as a second-line treatment for a similar group of patients.

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